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高橋 朋子 タカハシ トモコ

所属部署名 理工学研究科生命科学部門 電話番号
職名 助教 ■FAX番号
住所 さいたま市桜区下大久保255 埼玉大学理学部3号館 ■メールアドレス
■ホームページURL https://researchmap.jp/tomokotakahas

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兼担研究科・学部

理学部 分子生物学科

学歴

出身大学院・研究科等
2014 , 東京大学 , 博士後期 , 大学院理学系研究科 , 生物化学専攻 , 修了
取得学位
博士(理学) , 東京大学

研究活動業績

研究業績(著書・発表論文等)

論文
Establishing an efficient protoplast transient expression system for investigation of floral thermogenesis in aroids
Plant Cell Rep.,41(1):263-275 2022
Maekawa H, Otsubo M, Sato MP, Takahashi T, Mizoguchi K, Koyamatsu D, Inaba T, *Ito-Inaba Y

Mammalian antiviral systems directed by small RNA
PLoS Pathog. ,17:e1010091 2021
*Takahashi T, Heaton SM, *Parrish NF

TRBP-Dicer interaction enhances HIV-1 TAR RNA translation via TAR microRNA processing, repressing host-cell apoptosis.
Biol. Open,9(2):bio050435 2020
Komori C, Takahashi T, Nakano Y, *Ui-Tei K.

Mutual regulation of RNA silencing and the IFN response as an antiviral defense system in mammalian cells.
Int. J. Mol. Sci.,21:E1348 2020
*Takahashi T, *Ui-Tei K.

LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection.
Nucleic Acids Res.,48(3):1494-1507 2019
Takahashi T, Nakano Y, Onomoto K, Yoneyama M, *Ui-Tei K.

Current Status for Application of RNA Interference Technology as Nucleic Acid Drug.
InTechOpen “Gene Expression and Regulation in Mammalian Cells”:149-162 2018
Takahashi T, Nakano Y, *Ui-Tei K.

Takahashi T, Nakano Y, Onomoto K, Murakami F, Komori C, Suzuki Y, Yoneyama M, *Ui-Tei K.
Nucleic Acids Res.,46(17):9134-9147 2018
LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs.

Virus sensor RIG-I represses RNA interference by interacting with TRBP through LGP2 in mammalian cells.
Genes,9:511 2018
Takahashi T, Nakano Y, Onomoto K, Yoneyama M, *Ui-Tei K.

Chemical modification of the siRNA seed region suppresses off-target effects by steric hindrance to base-pairing with targets.
ACS Omega,2:2055-2064 2017
Iribe H, Miyamoto K, Takahashi T, Kobayashi Y, Leo J, Aida M, *Ui-Tei K.

Control of the localization and function of a miRNA silencing component TNRC6A by Argonaute protein.
Nucleic Acids Res.,43(20):9856-9873 2015
Nishi K, Takahashi T, Suzawa M, Miyakawa T, Nagasawa T, Ming Y, Tanokura M, *Ui-Tei K

The siRNA Non-Seed Region and its Target Sequences are Auxiliary Determinants of Off-Target Effects.
PLoS Comput. Biol.,11(12):e1004656 2015
Kamola PJ, Nakano Y, Takahashi T, Wilson PA, *Ui-Tei K

Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells.
Nucleic Acids Res.,42(8):5256-5269 2014
Takahashi T, Zenno S, Ishibashi O, Takizawa T, Saigo K, *Ui-Tei K

Distinguishable In Vitro Binding Mode of Monomeric TRBP and Dimeric PACT with siRNA
PLoS ONE,8:e63434 2013
Takahashi T, Miyakawa T, Zenno S, Nishi K, Tanokura M, *Ui-Tei K

Thermodynamic control of small RNA-mediated gene silencing.
Front. Genet.,3:101 2012
*Ui-Tei K, Nishi K, Takahashi T, Nagasawa T

The role of multiple HLR1 sequences in the regulation of the dual promoters of the psaAB genes in Synechocystis sp. PCC 6803.
J. Bacteriol.,192(15):4031-4036 2010
Takahashi T, Nakai N, Muramatsu M, *Hihara Y

The response regulator RpaB binds to the upstream element of photosystem I genes to work for positive regulation under low-light conditions in Synechocystis sp. Strain PCC 6803.
J. Bacteriol.,191(5):1581-1586 2009
Seino Y, Takahashi T, *Hihara Y

The regulation of persistent Borna disease virus infection by RNA silencing factors in human cells
Biochemical and Biophysical Research Communications
Kaneko Y, Naito Y, Koide R, Parrish NF, *Takahashi T