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川村　隆三 カワムラ リュウゾウ

■所属部署名 理工学研究科 物質科学専攻 ■電話番号
■職名 准教授 ■FAX番号
■住所 埼玉県さいたま市桜区下大久保255 ■メールアドレス
■ホームページURL https://sites.google.com/view/su-chem-kawalab

プロフィール

兼担研究科・学部

理学部

COE・クラスタ・研究グループ

基礎化学プログラム , 川村研究室

学歴

出身大学院・研究科等
2008 , 北海道大学 , 博士 , 理学研究科 , 生物科学専攻 , 単位取得満期退学
2005 , 東京工業大学 , 修士 , 生命理工学研究科 , 生命情報専攻 , 修了
出身学校・専攻等(大学院を除く)
2002 , 東京工業大学 , 生命理工学部 , 生物工学科 , 卒業
取得学位
博士（理学） , 北海道大学
修士（工学） , 東京工業大学

受賞学術賞

2019 , 第66回応用物理学会春季講演会 Poster Award , 「バーチャル電極ディスプレイによる微小管滑走制御の局所性評価」 　畑澤 研太、宮廻 裕樹、川村 隆三、星野 隆行
2017 , Outstanding Reviewer for Integrative Biology in 2016

研究活動業績

研究業績(著書・発表論文等)

著書
Chapter 40 "Employing Cytoskeletal Treadmilling in Bio-actuators" in “Soft Actuators 2nd edition"
Springer:711-722 201909
ISBN:978-981-13-6849-3
Ryuzo Kawamura, Ken-Ichi Sano, Yoshihito Osada

Hydrogels of Cytoskeletal Proteins —Preparation, Structure, and Emergent Functions
Springer International Publishing, Switzerland 201602
ISBN:978-3-319-27377-8
Yoshihito Osada, Ryuzo Kawamura, Ken-Ichi Sano

論文
Mechanical guidance of self-condensation patterns of differentiating progeny.
iScience,25(10):105109 2022
Takahisa Matsuzaki, Yuko Shimokawa, Hiroyuki Koike, Masaki Kimura, Yuma Kawano, Nao Okuma, Ryuzo Kawamura, Yosuke Yoneyama,Yasuro Furuichi, Fumihiko Hakuno, Shin-Ichiro Takahashi, Seiichiro Nakabayashi, Satoshi Okamoto, Hiromitsu Nakauchi, Hideki Taniguchi, Takanori Takebe, Hiroshi Y. Yoshikawa.

Surface-limited reactions for spatial control of kinesin–microtubule motility assays using indirect irradiation of an electron beam.
Biomicrofluidics,16:064105 2022
Hiroki Miyazako, Ryuzo Kawamura, Takayuki Hoshino.

Chiral Optical Force Generated by a Superchiral Near-Field of a Plasmonic Triangle Trimer as Origin of Giant Bias in Chiral Nucleation: A Simulation Study
J Phys. Chem. C,125(11):6209-6221 2021
Hiromasa Niinomi, Teruki Sugiyama, An-Chieh Cheng, Miho Tagawa, Toru Ujihara, Hiroshi Y. Yoshikawa, Ryuzo Kawamura, Jun Nozawa, Junpei T. Okada, and Satoshi Uda.

Intelligent gels-artificial soft tissue for the next era.
Polym. Int.,71(6):616-629 2021
Ken-Ichi Sano, Ryuzo Kawamura, Yoshihito Osada.

Plasmonic Manipulation of Sodium Chlorate Chiral Crystallization: Directed Chirality Transfer via Contact-Induced Polymorphic Transformation and Formation of Liquid Precursor
Cryst. Growth & Des.,20:5493-5507 2020
Hiromasa Niinomi, Teruki Sugiyama, Miho Tagawa, Toru Ujihara, Takashige Omatsu, Katsuhiko Miyamoto, Hiroshi Y. Yoshikawa, Ryuzo Kawamura, Jun Nozawa, Junpei T. Okada, and Satoshi Uda.

Stiffness distribution analysis in indentation depth direction reveals clear mechanical features of cells and organoids by using AFM
Appl. Phys. Express.,13:097001 2020
Naritaka Kobayashi, Shodai Togo, Takahisa Matsuzaki, Kaede Hashiseko, Ryuzo Kawamura, Masami Suganuma, Seiichiro Nakabayashi, Yosuke Yoneyama, Rie Ouchi, Takanori Takebe, and Hiroshi Y Yoshikawa.

Quantitative Evaluation of the Impact of Artificial Cell Adhesion via DNA Hybridization on E-cadherin-Mediated Cell Adhesion.
APL Bioengineering,4:016103 (8 pages) 2020
Shodai Togo, Ken Sato, Ryuzo Kawamura, Naritaka Kobayashi, Makoto Noiri, Seiichiro Nakabayashi, Yuji Teramura, and Hiroshi Y. Yoshikawa

Simultaneous atomic-resolution flexural and torsional imaging in liquid by frequency modulation atomic force microscopy
Jpn. J. Appl. Phys.,59:SIII01 2020
Megumi Umemoto, Ryuzo Kawamura, Hiroshi Y. Yoshikawa, Seiichiro Nakabayashi, Naritaka Kobayashi

Reversible surface functionalization of motor proteins for sustainable motility
Jpn. J. Appl. Phys.,58:SDDI01 2019
Keisuke Meguriya, Shiori Kikuchi, Naritaka Kobayashi, Hiroshi Y. Yoshikawa, Seiichiro Nakabayashi, Ryuzo Kawamura

Start/Stop Motion Control of a Targeted Microtubule Using Virtual Cathode Display
Biochem. Biophys. Res. Comm.,514:821–825 2019
Kenta Hatazawa, Hiroki Miyazako, Ryuzo Kawamura, Takayuki Hoshino

“Employing Cytoskeletal Treadmilling in Bio-Actuators”
Soft Actuators – Materials, Modelling, Applications, and Future Perspectives (2nd edition). Edited by Kinji Asaka and Hidenori Okuzaki (Springer),(in press) 2019
Ryuzo Kawamura, Ken-ichi Sano, and Yoshihito Osada

Light-Powered Nanoconverters Cytotoxic to Breast Cancer Cells
Journal of Physical Chemistry,122:7916-7924 2018
Alexandre R. Loukanov, Alexei G. Basnakian, Ryuzo Kawamura, Hibiki Udono, Chavdar K. Filipov, Alena V. Savenka, Todd Fite, Seiichiro Nakabayashi

Structural change of nonionic surfactant self-assembling at electrochemically controlled HOPG/electrolyte interface
Journal of Electroanalytical Chemistry,799:444-450 2017
Naritaka Kobayashi, Hirokazu Saitoh, Ryuzo Kawamura, Hiroshi Y. Yoshikawa, Seiichiro Nakabayashi

Monitoring and extraction of uranium in polluted acid mine drainage by super-paramagnetic nanoparticles coated with carbon nanodots
Journal of Radioanalytical and Nuclear Chemistry,314(2):1149-1159 2017
Alexandre Loukanov, Hibiki Udono, Ryo Takakura, Polina Mladenova, Naritaka Kobayashi, Ryuzo Kawamura, Seiichiro Nakabayashi

A new cell separation method based on antibody-immobilized nanoneedle arrays for the detection of intracellular markers
Nano Letters,17(11):7117-7124 2017
Ryuzo Kawamura, Minami Miyazaki, Keita Shimizu, Yuta Matsumoto, Yaron R. Silberberg,　Ramachandra Rao Sathuluri, Masumi Iijima, Shun’ichi Kuroda, Futoshi Iwata, Takeshi Kobayashi, Chikashi Nakamura

Design of polymer networks involving a photoinduced electronic transmission circuit toward artificial photosynthesis
Langmuir,32:626-631 2016
Kosuke Okeyoshi, Ryuzo Kawamura, Ryo Yoshida, Yoshihito Osada

Investigation on nanoscale processes on the BaF2(111) surface in various solutions by frequency modulation atomic force microscopy
Journal of Applied Physics,119:214308 2016
Naritaka Kobayashi, Ryuzo Kawamura, Hiroshi Y Yoshikawa, Seiichiro Nakabayashi

Kinesin-Driven Active Substrate Giving Stochastic Mechanical Stimuli to Cells for Characterization
ACS Biomaterials Science & Engineering,2:2333-2338 2016
Ryuzo Kawamura, Daiki Uehara, Naritaka Kobayashi, Seiichiro Nakabayashi, Hiroshi Y Yoshikawa

High efficiency penetration of antibody-immobilized nanoneedle thorough plasma membrane for in situ detection of cytoskeletal proteins in living cells
Journal of Nanobiotechnology,14:74 2016
Ryuzo Kawamura, Keita Shimizu, Yuta Matsumoto, Ayana Yamagishi, Yaron R Silberberg, Masumi Iijima, Shun’ichi Kuroda, Kyoko Fukazawa, Kazuhiko Ishihara, Chikashi Nakamura

Design of polymer networks involving a photoinduced electronic transmission circuit toward artificial photosynthesis
Langmuir,32:626–631 2016
Kosuke Okeyoshi, Ryuzo Kawamura, Ryo Yoshida, Yoshihito Osada

Effect of microtubule polymerization on photoinduced hydrogen generation
Chemical Communications,51:11607–11610 2015
Kohsuke Okeyoshi, Ryuzo Kawamura, Ryo Yoshida, Yoshihito Osada

Oscillating high-aspect-ratio monolithic silicon nanoneedle array enables efficient delivery of functional bio-macromolecules into living cells
Scientific Reports,5:15325 2015
Daisuke Matsumoto, Ramachandra Rao Sathuluri, Yoshio Kato, Yaron R. Silberberg, Ryuzo Kawamura, Futoshi Iwata, Takeshi Kobayashi, Chikashi Nakamura

Microtubule teardrop patterns
Scientific Reports,5:9581 2015
Kohsuke Okeyoshi, Ryuzo Kawamura, Ryo Yoshida, Yoshihito Osada

Chemically cross-linked microtubule assembly shows enhanced dynamic motions on kinesins
RSC Advances,4:32953 2014
Ryuzo Kawamura, Ken-ichi Sano, Kuniharu Ijiro, Yoshihito Osada

Measurement of cell adhesion force by vertical forcible detachment using an arrowhead nanoneedle and AFM
Biochem. Biophys. Res. Commun,451:107 2014
Seunghwan Ryu, Yui Hashizume, Mari Mishima, Ryuzo Kawamura, Masato Tamura, Hirofumi Matsui Michiya Matsusaki, Mitsuru Akashi, Chikashi Nakamura

Controlling the bias of rotational motion of ring-shaped　microtubule assembly
Biomacromolecules,16:374 2014
Shoki Wada, Arif Md.　Rashedul Kabir, Ryuzo Kawamura, Masaki Ito, Daisuke Inoue,　Kazuki Sada, Akira Kakugo

Detection of microtubules in vivo using antibody-immobilized nanoneedles
J. Biosci. Bioeng.,117:107–112 2014
Yaron Silberberg, Ryuzo Kawamura, Seunghwan Ryu, Kyoko Fukazawa, Kazuhiko Ishihara, Chikashi Nakamura

学会発表
Enhanced movement of kinesin-driven microtubules by crosslink and the application as active material
Nakabayashi-Yoshikawa Lab., Saitama University,International Workshop on “Emergence of Life-Nano-Bio Science” 2021
Ryuzo Kawamura

Construction of Kinesin-Driven Active Substratewith Improved Uniformity and Reproducibility toward Quantitative Analysis
NMC2019 202005
K. Meguriya, T. Yokoyama, N.Kobayashi, H.Y. Yoshikawa, S. Nakabayashi and R. Kawamura

Simultaneous Atomic-Resolution Flexuraland Torsional Imaging in Liquidby Frequency Modulation Atomic Force Microscopy
MNC2019 202005
M. Umemoto, R. Kawamura, H.Y. Yoshikawa, S. Nakabayashi and N. Kobayashi

細胞骨格タンパク質を利用した動的ゲル材料の開発
高分子埼玉地区懇話会 202003
川村隆三

ATP-fueled active network of microtubules as a dynamic environemnt for cells
2nd GLowing Polymer Symposium in KANTO 201911
Ryuzo Kawamura

Active network of motor proteins as artificial dynamic microenvironment for cells
ISAGMSM (The 3rd International Symposium for Advanced Gel Materials & Soft Matters) 201906
Ryuzo Kawamura, Keisuke Meguriya, Tsuyoshi Yokoyama, Daiki Uehara, Naritaka Kobayashi, Seiichiro Nakabayashi, Hiroshi Y. Yoshikawa

Temporal-Stop of Microtubule Movement by Electrical Stimulation on Virtual Cathode
MNC 2018 (31st International Microprocesses and Nanotechnology Conference) 201811
Kenta Hatazawa, Hiroki Miyazako, Ryuzo Kawamura and Takayuki Hoshino

Removal of Surface Adsorbed Kinesin by Multi-Photon Laser Ablation and Reloading toward Arbitral Patterning of Microtubule Driving Track
MNC 2018 (31st International Microprocesses and Nanotechnology Conference) 201811
Keisuke Meguriya, Shiori Kikuchi, Naritaka Kobayashi, Hiroshi Y. Yoshikawa, Seiichiro Nakabayashi and Ryuzo Kawamura

Building up a Multi-Channel Flow System to Analyze Cellular Mechanical Behavior Utilizing Dynamic Network of Microtubule Gel Driven by Kinesins
Gel Sympo 2018,4DMS 201808
Ryuzo Kawamura, Tsuyoshi Yokoyama, Keisuke Meguriya, Naritaka Kobayashi, Seiichiro Nakabayashi, Hiroshi Y. Yoshikawa

キネシン駆動型運動界面による接着細胞の力学刺激環境構築
第11回バイオ関連化学シンポジウム 201709
川村隆三、横山剛志、上原大樹、小林成貴、中林誠一郎、吉川洋史

キネシン・微小管の運動集積化と動的細胞環境としての応用
分子モーター討論会 201707
川村隆三

Kinesin-driven active substrate for cells giving mechanical noise stimuli
日本化学会第97回春季年会 201703
Ryuzo Kawamura, Daiki Uehara, Naritaka Kobayashi, Seiichiro Nakabayashi, Hiroshi Y Yoshikawa

Cross-linked microtubule network driven by kinesin as bio-active matter
第67回コロイドおよび界面化学討論会 201609
Ryuzo Kawamura, Daiki Uehara, Naritaka Kobayashi, Seiichiro Nakabayashi, Hiroshi Y Yoshikawa

Dynamic substrate driven by motor proteins for mechanical cellular stimuli
第５３回日本生物物理学会年会 201609
川村 隆三, 上原 大樹 , 小林 成貴 , 中林 誠一郎 , 吉川 洋史

Motor protein-driven active substrate for detection of cellular mechanical response
11th International Conference and Workshop on BIOLOGICAL BARRIERS 201603
Ryuzo Kawamura, Daiki Uehara, Naritaka Kobayashi, Seiichiro Nakabayashi, Hiroshi Yoshikawa

キネシン・微小管を用いた運動界面構築と細胞培養基板としての応用
「第５回 次世代の物質科学・ナノサイエンスを探る」「知の協奏を目指すソフトおよびナノマテリアル研究会2016」共同開催 201601
川村隆三, 上原 大樹 , 小林 成貴 , 中林 誠一郎 , 吉川 洋史

細胞の力学刺激を目的としたキネシン駆動型運動界面の構築
文部科学省科学研究費補助金新学術領域　「ナノメデイシン分子科学」＋「超高速バイオアセンブラ」合同若手の会 201510
川村隆三, 上原 大樹 , 小林 成貴 , 中林 誠一郎 , 吉川 洋史

Kinesin-driven microtubule network for mechanical cellular stimuli
iCeMS International Symposium　Hierarchical Dynamics in Soft Materials and Biological Matter 201509
Ryuzo Kawamura, Daiki Uehara, Naritaka Kobayashi, Seiichiro Nakabayashi, Hiroshi Yoshikawa

研究費

科学研究費補助金(研究代表者)
2019-2022 , 運動界面によるがん細胞の転移性評価指標の導出 , 基盤研究(C)
科学研究費補助金(研究分担者)
2020-2022 , 光物理的アプローチによる細胞骨格形成の自在制御技術の開発 , 挑戦的研究(萌芽)
2019-2023 , レーザー技術による機能性分子の秩序構造形成制御 , 国際共同研究強化(B)
2019-2022 , 超高速分子ディスプレイを用いた分子知能機械の研究 , 基盤研究(B)
その他公的資金
2021-2022 , モータータンパク質駆動型揺らぎプロセッサの創成, JKA研究補助（複数年）