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菅沼 雅美 スガヌマ マサミ

所属部署名 理工学研究科 電話番号
職名 教授 ■FAX番号
住所 埼玉県さいたま市桜区下大久保255 ■メールアドレス
■ホームページURL

研究活動業績

研究業績(著書・発表論文等)

論文
Down-regulation of histone deacetylase 4, -5 and -6 as a mechanism of synergistic enhancement of apoptosis in human lung cancer cells treated with the combination of a synthetic retinoid, Am80 and green tea catechin
,Journal of Nutritional Biochemistry,42:7-16 2017
Oya, Y., Mondal, A., Rawangkan, A., Umsumarng, S., Iida, K., Watanabe, T., Kanno, M., Suzuki, K., Li, Z., Kagechika, H., Shudo, K., Fujiki, H., Suganuma, M.

Phorbol esters in seed oil of Jatropha curcas L/ (saboodam in Thai) and their association with cancer prevention: from the initial investigation to the present topics
,J Cancer Res Clin Oncol 2017
Fujiki, H., Suttajit, M., Rawangkan, A., Iida, K., Limtrakul, P., Umsumarng S., Suganuma, M.

Biophysical approach to mechanisms of cancer prevention and treatment with green tea catechins
,Molecules,21:1566 2016
Suganuma, M., Takahashi, A., Watanabe, T., Iida, K., Matsuzaki, T., Yohikawa, H, Y., Fujiki, H.

Quantitative Evaluation of Cancer Cell Adhesion to Self-Assembled Monolayer-Patterned Substrates by Reflection Interference Contrast Microscopy
,Journal of Physical Chemistry B,120:1221-1227 2016
Matsuzaki, T., Ito, K., Masuda, K., Kakinuma, E., Sakamoto, R., Iketaki, K., Yamamoto, H., Suganuma, M., Kobayashi, N., Nakabayashi, S., Tanii, T., and Yoshikawa, HY.

Synergistic enhancement of anticancer effects on numerous human cancer cell lines treated with the combination of EGCG, other green tea catechins, and anticancer compounds
,J. Cancer Res. Clin Oncol. ,141:1511-1522 2015
Fujiki, H., Sueoka, E., Watanabe, T. and Suganuma, M.

Abrogation of protein phosphatase 6 promotes skin carcinogenesis induced by DMBA
,Oncogene,34:4647-4655 2015
Hayashi, K., Momoi, Y., Tanuma, N., Kishimoto, A., Ogoh, H., Kato, H., Suzuki, M., Sakamoto, Y, Inoue, Y., Nomura, M., Kiyonari, H., Sakayori, M., Fukamachi, K., Kakugawa, Y., Yamashita, Y., Ito, S., Sato, I., Suzuki, A., Nishio, M., Suganuma, M., Watanabe, T. and Shima, H.

Primary cancer prevention by green tea, and tertiary cancer prevention by the combination of green tea catechins and anticancer compounds
,J. Cancer Prev.,20:1-4 2015
Fujiki, H., Sueoka, E., Watanabe, T. and Suganuma, M.

Innovative strategy of cancer treatment with the combination of green tea catechins and anticancer compounds
,Cancer Cell Microenvironment,2:e886 2015
Fujiki, H., Imai, K., Nakachi, K., Sueoka, E., Watanabe, T. and Suganuma, M

Progressive Insight into tumor promotion with proinflammatory cytokines
,SOJ Immunology:1-4 2015
Fujiki, H., Sueoka, E., Watanabe, T. and Suganuma, M

Highlights of the Twelfth Japan-Korea Joint Symposium on Cancer and Ageing Research
,J Cancer Res Clin Oncol,,141:1953-1961 2015
Suganuma, M., Park, TJ., Sueoka, E., Iida, K., Tanaka, Y.

Cell-surface nucleolin acts as a central mediator for carcinogenic, anti-carcinogenic, and disease-related ligands
,J. Cancer Res. Clin. Oncol.,140:689-699 2014
Fujiki, H., Watanabe, T. and Suganuma, M.

Green tea aroma fraction reduces ß -amyloid peptide-induced toxicity in Caenorhabditis elegans transfected with human ß-amyloid minigene
,Biosci. Biotech. Biochem.,78:1206-1211 2014
Takahashi, A., Watanabe, T., Fujita, T., Hasegawa, T., Saito, M. and Suganuma, M.

Mechanism-based inhibition of cancer metastasis with (-)-epigallocatechin gallate
,Biochem. Biophys. Res. Commun.,443:1-6 2014
Takahashi, A., Watanabe, T., Anupom, M., Suzuki, K., Kurusu-Kanno, M., Li, Z., Fujiki, H., Yamazaki, T., and Suganuma, M.

Epithelial-mesenchymal transition in human gastric cancer cell lines induced by TNF-α inducing protein of Helicobacter pylori
,Int. J. Cancer,134:2373-2382 2014
Watanabe, T., Takahashi, A., Suzuki, K., Kurusu-Kanno, M., Yamaguchi, K., Fujiki, H., and Suganuma, M.

Tumor promoters: from chemicals to inflammatory proteins
,J. Cancer Res. Clin. Oncol.,139:1603-1614 2013
Fujiki, H., Sueoka, E. and Suganuma, M.

Higher cell stiffness indicating lower metastatic potential in B16 melanoma cell variants and in (-)-epigallocatechin gallate-treated cells
,J. Cancer Res. Clin. Oncol.,138:859-866 2012
Watanabe, T., Kuramochi, H., Takahashi, A., Imai, K., Katsuta, N., Nakayama,T., Fujiki, H., Suganuma, M.

Human gastric cancer development with TNF-α-inducing protein secreted from Helicobacter pylori
,Cancer Lett.,322:133-138 2012
Suganuma, M., Watanabe, T., Yamaguchi, K., Takahashi, A., and Fujiki, H.

Challenging the effectiveness of green tea in primary and tertiary cancer prevention.
,J. Cancer Res. Clin. Oncol.,138:1259-1270 2012
Fujiki, H., Imai, K., Nakachi, K., Shimizu, M., Moriwaki, H. and Suganuma, M.

Green tea: An effective synergist with anticancer drugs for tertiary cancer prevention
,Cancer Lett.,324:119-125 2012
Fujiki, H. and Suganuma, M.

Challenging the effectiveness of green tea in primary and tertiary cancer prevention
,J. Cancer Res. Clin. Oncol.,138:1259-1270 2012
Fujiki, H., Imai, K., Nakachi, K., Shimizu, M., Moriwaki, H. and Suganuma, M.

Tumor promotion by TNF-α-inducing protein and its receptor nucleolin in human gastric carcinogenesis by Helicobacter pylori
,Trends Cancer Res. ,8:97-112 2012
Fujiki, H., Watanabe, T. and Suganuma, M.

New cancer treatment strategy using combination of green tea catechins and anticancer drugs
,Cancer Sci.,102:317-323 2011
Suganuma, M., Saha, A. and Fujiki, H.

Tumor promoters - Microcystin-LR, nodularin and TNF-α and human cancer development
,Anti-Cancer Agents Med. Chem.,11:4-18 2011
Fujiki, H. and Suganuma, M.

Nucleolin as cell surface receptor for tumor necrosis factor-α inducing protein: A carcinogenic factor of Helicobacter pylori
,J. Cancer Res. Clin. Oncol.,136:911-921 2010
Watanabe, T., Tsuge, H., Imagawa, T., Kise, D., Hirano, K., Beppu, M., Takahashi, A., Yamaguchi, K., Fujiki, H. and Suganuma, M.

Neocomplanines A and B, a complanine family isolated from the marine fireworm
,J. Nat. Prod.,73:303-305 2010
Nakamura, K., Tachikawa, Y., Ohono, O., Kitamura, M., Suganuma, M. and Uemura, D.

Nucleolin on the cell surface as a new molecular target for gastric cancer treatment
,Biol. Pharm. Bull.,33:796-803 2010
Watanabe, T., Hirano, K., Takahashi, A., Yamaguchi, K., Beppu, M., Fujiki, H. and Suganuma, M.

New role of (-)-epicatechin in enhancing the induction of growth inhibition and apoptosis in human lung cancer cells by curcumin
,Cancer Prev. Res.,3(8):953-962 2010
Saha, A., Kuzuhara, T., Echigo, N., Suganuma, M. and Fujiki, H.

Apoptosis of human lung cancer cells by curcumin mediated through up-regulation of “growth arrest and DNA damage inducible genes 45 and153
,Biol. Pharm. Bull.,33(8):1291-1299 2010
Saha, A, Kuzuhara, T., Echigo, N., Fujii, A., Suganuma, M. and Fujiki, H.

Carcinogenic aspects of protein phosphatase 1 and 2A inhibitors
,(N., Fusetani and W. Kem eds), In: Marine Toxins as Research Tools Springer-Verlag Berlin Heidelberg:221-254 2009
Fujiki, H. and Suganuma, M.

Structural basis for the Helicobacter pylori-carcinogenic TNF-α-inducing protein
,Biochem. Biophys. Res. Commun.,388:193-198 2009
Tsuge, H., Tsurumura, T., Utsunomiya, H., Kise, D., Kuzuhara, T., Watanabe, T., Fujiki, H., Suganuma, M.

Evaluation of a new tumor necrosis factor-α-inducing membrane protein of Helicobacter pylori as a prophylactic vaccine antigen
,Helicobacter,14:487-495 2009
Inoue, K., Shiota, S., Yamada, K., Gotoh, K., Suganuma, M., Fujioka T., Ahmed K., Iha H., Nishizono, A.

Green tea catechin as a chemical chaperone in cancer prevention
,Cancer Lett.,261:12-20 2008
Kuzuhara, T., Suganuma, M. and Fujiki, H.

TNF-α-inducing protein, a carcinogenic factor secreted from H. pylori, enters gastric cancer cells
,Int. J. Cancer,123:117-122 2008
Suganuma, M., Yamaguchi, K., Ono, Y., Matsumoto, H., Hayashi, T., Ogawa, T., Imai, K., Kuzuhara, T., Nishizono, A. and Fujiki, H.

Complanine, an inflammation-inducing substance isolated from the marine fireworm Eurythoe complanata
,Org. Biomol. Chem.,6:2058-2060 2008
Nakamura, K., Tachikawa, Y., Kitamura, M., Ohno, O., Suganuma, M. and Uemura, D.

Generation of mouse monocolonal antibody against (-)-epigallocatechin gallate
,Biol. Pharm. Bull.,31:816-819 2008
Kuzuhara, T., Kise, D., Shirakawa, Y., Sasada, K., Suganuma, M. and Fujiki, H.

Macrocyclic hexaoxazoles as sequence- and mode-selective G-quadruplex binders
,Angew. Chem. Int.,47:5557-5560 2008
Tera, M., Ishizuka, H., Takagi, M., Suganuma, M., Shin-ya, K. and Nagasawa K.

Antiproliferative and apoptosis-inducing activities of alkyl gallate and gallamide derivatives related to (−)-epigallocatechin gallate
,Bioorg. Med. Chem.,16:7975-7982 2008
Dodo, K., Minato, T., Noguchi-Tachida, T., Suganuma, M. and Hashimoto, Y.

Green tea extracts for the prevention of metachronous colorectal adenomas: A pilot study
,Cancer Epidemiol. Biomarkers Prev.,17:3020-3025 2008
Shimizu M., Fukutomi, Y., Ninomiya, M., Nagura, K., Kao, T., Arai, H., Suganuma, M., Fujiki, H. and Moriwaki, H.

Helicobacter pylori-secreting protein Tipα is a potent inducer of chemokine gene expressions in stomach cancer cells
,J. Cancer Res. Clin. Oncol.,133:287-296 2007
Kuzuhara, T., Suganuma, M., Kurusu, M. and Fujiki, H.

Synergistic effects of multiple treatments, and both DNA and RNA direct bindings on, green tea catechins
,Mol. Carcinogen.,46:640-645 2007
Kuzuhara, T., Tanabe, A., Sei, Y., Yamaguchi, K., Suganuma, M. and Fujiki, H.

DNA-binding activity of TNF-α inducing protein from Helicobacter pylori
,Biochem. Biophys. Res. Commun.,362:805-810 2007
Kuzuhara, T., Suganuma, M., Oka, K. and Fujiki, H.

Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by up-regulation of GADD153 gene
,Int. J. Cancer,119:33-40 2006
Suganuma, M., Kurusu, M., Suzuki, K., Tasaki, E. and Fujiki H.

DNA and RNA as new binding targets of green tea catechins
,J. Biol. Chem.,25:17446-17456 2006
Kuzuhara, T., Sei, Y., Yamaguchi, K., Suganuma, M. and Fujiki, H.

Carcinogenic role of tumor necrosis factor-α inducing protein of Helicobacter pylori in human stomach.
,J. Biochem. Mol. Biol.,39:1-8 2006
Suganuma, M., Kuzuhara, T., Yamaguchi, K., and Fujiki, H.

New tumor necrosis factor-α-inducing protein released from Helicobacter pylori for gastric cancer progression
,J. Cancer. Res. Clin. Oncol. ,131:305-313 2005
Suganuma, M., Kurusu, M., Suzuki, K., Nihizono, A., Murakami, K., Fujioka, T., and Fujiki, H.

Presence of motif conserved between Helicobacter pylori TNF-α inducing protein (Tipα) and penicillin binding proteins
,Biol. Pharm. Bull.,28:2133-2137 2005
Kuzuhara, T., Suganuma, M., Tsuge, H. and Fujiki, H.

Cancer prevention with green tea polyphenols for the general population, and for patients following cancer treatment
,Current Cancer Therapy Rev.,1:109-114 2005
Fujiki, H., Suganuma, M., Matsuyama, S., and Miyazaki, K.

Translational research on TNF-α as an endogenous tumor promoter and green tea as cancer preventive in humans
,J. Env. Sci. Health,23:3-30 2005
Fujiki, H., Suganuma, M.

Carcinogenic potential of tobacco tar-resistant Staphylcoccus aureus in buccal cavity
,J. Cancer Res. Clin. Oncol. ,130:301-305 2004
Fujiki, H., Takeuchi, H., Nishitani, N., Yamanaka, H., Suzuki, K., Kurusu, M., and Suganuma, M.

Mice lacking a transcriptional corepressor Tob are predisposed to cancer
,Genes & Development,17:1201-1206 2003
Yoshida, Y., Nakamura, T., Komoda, M., Satoh, H., Suzuki, T., K. Tsuzuku, J., Miyasaka, T., H. Yoshida, E., Umemori, H., K. Kunisaki, R., Tani, K., Ishii, S., Mori, S.,Suganuma, M., Noda, T. and Yamamoto, T.

Isolation and synthesis of TNF-αrelease inhibitors from Fijian kawa (Piper methysticm).
,Phytomedicine,10:309-317 2003
Hashimoto, T., Suganuma, M., Fujiki, H., Yamada, M., Kohno, T. and Asakawa, Y.

New TNF-α releasing inhibitors as cancer preventive agents from traditional herbal medicine and combination cancer prevention study with EGCG and sulindac or tamoxifen
,Mutat. Res.,523-524:119-125 2003
Fujiki, H., Suganuma, M., Kurusu, M., Okabe, S., Imayoshi, Y., Taniguchi, S. and Yoshida, T.

Discrete roles of cytokines, TNF-α, IL-1, IL-6 in tumor promotion and cell transformation
,Int. J. Oncol.,20:131-136 2002
Suganuma, M., Okabe, S., Kurusu, M., Iida, N., Ohshima, S., Saeki, Y., Kishimoto, T. and Fujiki, H.

Lung cancer prevention with (-)-epigallocatechin gallate using monitoring by heterogeneous nuclear ribonucleoprotein B1
,Int. J. Oncology,20:1233-1239 2002
Fujimoto, N., Sueoka, N., Sueoka, E., Okabe, S., Suganuma, M., Harada, M. and Fujiki, H.

Green tea and cancer prevention,
,Proc. Jpn. Acad.,78:263-270 2002
Fujiki, H. and Suganuma, M.

Green tea: Cancer preventive beverage and/or drug
,Cancer Lett. ,188:9-13 2002
Fujiki, H., Suganuma, M., Imai, K. and Nakachi, K.

Involvement of TNF-α changes in human cancer development, prevention and palliative care
,Mech. Ageing Dev. ,123:1655-1663 2002
Fujiki, H., Suganuma, M., Okabe, S., Kurusu, M., Imai, K. and Nakachi, K.

Combination cancer chemoprevention with green tea extract and sulindac shown in intestinal tumor promotion in Min mice
,J. Cancer. Res. Clin. Oncol.,127:69-72 2001
Suganuma, M., Ohkura Y., Okabe, S. and H. Fujiki.

A new function of green tea: Prevention of lifestyle-related diseases
,Healthy Aging for Functional Longevity,928:274-280 2001
Sueoka, N., Suganuma, M., Sueoka, E., Okabe, S., Matsuyama, S., Imai, K., Nakachi, K. and Fujiki, H.

Modulation of gene expression by (-)-epigallocatechin gallate in PC-9 cells using a cDNA expression array
,Biol. Pharm. Bull. ,24:883-886 2001
Okabe, S., Fujimoto, N., Sueoka, N., Suganuma, M. and Fujiki, H.

Helicobacter pyloi membrane protein 1, a new carcinogenic factor of Helicobacter pylori
,Cancer Res.,61:6356-6359 2001
Suganuma, M., Kurusu, M., Okabe, S., Sueoka, N., Yoshida, M., Wakatsuki, Y. and Fujiki, H.

Cancer prevention with green tea and monitoring by a new biomaker, hnRNP B1
,Mutation Res.,480-481:299-304 2001
Fujiki, H., Suganuma, M., Okabe, S., Sueoka, E., Sueoka, N., Fujimoto, N., Goto, Y., Matsuyama, S., Imai, K. and Nakachi, K.

New TNF-α releasing inhibitors, geraniin and corilagin, in leaves of Acer nikoense, Megusurino-ki
,Biol. Pharm. Bull. ,24:1145-1148 2001
Okabe, S., Suganuma, M., Imayoshi, Y., Taniguchi, S., Yoshida, T. and Fujiki, H.

Green tea as a cancer preventive
,(I. T. Johnson and G. R. Fenwick eds), In: Dietary Anticarcinogens and Antimutagens, Chemical and Biological Aspects Royal Society of Chemistry, Cambridge, U.K.:12-17 2000
Fujiki, H. Suganuma, M., Okabe, S., Sueoka, E., Sueoka, N., Matsuyama, S., Imai, K. and Nakachi, K.

The role of interleukin-6 in inhibition of lung metastasis in subcutaneous tumor-bearing mice
,Oncology Reports ,7:69-73 2000
Inoue, K., Okabe, S., Sueoka, E., Sueoka, N., Tabei, T. and Suganuma, M.

Syntheses of isocitric acid derivatives and biological evaluation
,Tetrahedron Letters,41:3095-3098 2000
Tori, M., Sono, Y., Nakashiba, Y., Hamada, N., Sono, M., Asakawa, Y., Suganuma, M., Okabe, S. and Fujiki, H.

Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention
,BioFactors,13:49-54 2000
Nakachi, K., Matsuyama, S., Miyake, S., Suganuma, M. and Imai, K.

Mechanisms of cancer prevention by tea polyphenols based on inhibition of TNF-αexpression
,BioFactors,13:67-72 2000
Suganuma, M., Sueoka, E., Sueoka, N., Okabe, S. and Fujiki, H.

A new concept of tumor promotion by tumor necrosis factor-α, and cancer preventive agents (-)-epigallocatechin gallate and green tea-a review
,Cancer Detect. Prev.,24:91-99 2000
Fujiki, H., Suganuma, M., Okabe, S., Sueoka, E., Suga, K., Imai, K. and Nakachi, K.

28-Deacetylbelamcandal, a tumor-promoting triterpenoid from iris tectorum
,J. Nat. Prod. ,62:291-293 1999
Takahashi, K., Hano, Y., Suganuma, M., Okabe, S. and Nomura, T.

Synergistic effects of (-)-epigallocatechin gallate with (-)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line, PC-9
,Cancer Res.,59:44-47 1999
Suganuma, M., Okabe, S., Kai, Y., Sueoka, N., Sueoka, E. and Fujiki, H.

Disaccharide esters screened for inhibition of tumor necrosis factor-α release are new anti cancer agents
,Jpn. J. Cancer Res.,90:669-676 1999
Okabe, S., Suganuma, M., Tada, Y., Ochiai, Y., Sueoka, E., Kohya, H., Shibata, A., Takahashi, M., Mizutani, M., Matsuzaki, T. and Fujiki, H.

Mechanistic aspects of green tea as a cancer preventive: Effect of components on human stomach cancer cell lines
, Jpn. J. Cancer Res.,90:733-739 1999
Okabe, S., Ochiai, Y., Aida, M., Park, K., Lim, S.-J., Nomura, T., Suganuma, M. and Fujiki, H.

Green tea and cancer chemoprevention
,Mutat. Res. ,428:339-344 1999
Suganuma, M., Okabe, S., Sueoka, N., Sueoka, E., Matsuyama, S., Imai, K., Nakachi, K. and Fujiki, H.

Essential role of tumor necrosis factorα(TNF-α) in tumor promotion as revealed by TNF-α deficient mice
,59:4516-4518 1999
Suganuma, M., Okabe, S., Marino, M. W., Sakai, A., Sueoka, E. and Fujiki, H.

Unique features of the okadaic acid activity class of tumor promoter
,J. Cancer Res. Clin. Oncol.,125:150-155 1999
Fujiki, H. and Suganuma, M.

Mechanistic findings of green tea as cancer preventive for humans
, In: Proceedings of the Society for Experimental Biology and Medicine,220: 225-228 1999
Fujiki, H., Suganuma, M., Okabe, S., Sueoka, E., Suga, K., Imai, K., Nakachi, K. and Kimura, S.

Natural inhibitors of carcinogenesis
,(Y. Martinet, et al.. eds), In: Clinical and Biological Basis of Lung Cancer Prevention, Birkhaser Verlag, Basel: 285-290 1998
Fujiki, H., Suganuma, M., Komori, A., Okabe, S., Sueoka, E., Sueoka, N., Kozu, T. and Tada, Y.

Twist form of teleocidin derivatives is active in in vivo tumor promotion by (-)-benzolactam-V8-310
,Biol. Pharm. Bull. ,21(5):465-468 1998
Okabe, S., Sueoka, N., Komori, A., Suganuma, M., Endo, Y., Shudo, K. and Fujiki, H.

Tumourigenicity of MTG8, a leukemia-related gene, in concert with v-Ha-ras gene in BALB/3T3 cells
,British J. Haemat.,101: 737-742 1998
Sueoka, E., Sueoka, N., Okabe, S., Komori, A., Suganuma, M., Kozu, T. and Fujiki, H.

Cancer inhibition by green tea
,Mutat. Res. ,402:307-310 1998
Fujiki, H., Suganuma, M., Okabe, S., Sueoka, N., Komori, A., Sueoka, E., Kozu, T., Tada, Y., Suga, K., Imai, K. and Nakachi, K.

Wide distribution of [3H]-(-)-epigallocatechin gallate, a cancer preventive tea polyphenol, in mouse tissue
,Carcinogenesis,19:1771-1776 1998
Suganuma, M., Okabe, S., Oniyama, M., Tada, Y., Ito, H. and Fujiki, H.

Growth inhibition of leukemic cells by (-)-epigallocatechin gallate, the main constituent of green tea
,Life Science,63:1397-1403 1998
Otsuka, T., Ogo, T., Eto, T., Asano, Y., Suganuma, M. and Niho, Y.

Anticancer activity of morphine and its synthetic derivative, KT-90, mediated through apoptosis and inhibition of NF-kB activation
,Biophys. Res. Commun.,252:566-570 1998
Sueoka, E., Sueoka, N., Kai, Y., Okabe, S., Suganuma, M., Kanematsu, K., Yamamoto, T. and Fujiki, H.

Mechanisms of (-)-epigallocatechin gallate and green tea in inhibition of carcinogenesis
,(H. Ohigashi, et al.. eds), In: Food Factors for Cancer Prevention, Springer, Tokyo:127-129 1997
Suganuma, M., Okabe, S., Oniyama, M., Sueoka, N., Kozu, T., Komori, A., Sueoka, E., Hara, E. and Fujiki, H.

Chemoprevention of cancer
,(G. T. Bowden and S. M. Fischer eds), In: Comprehensive Toxicology,12:453-471 1997
Fujiki, H., Komori, A. and Suganuma, M.

Tumor promotion and TNF-α gene expression by the okadaic acid class tumor promoters
,Envir. Carcino. & Ecotox. Revs.,C15(1):1-40 1997
Fujiki, H., Sueoka, E., Komori, A. and Suganuma, M.

Mechanisms of growth inhibition of human lung cancer cell line, PC-9, by tea polyphenols
,Jpn. J. Cancer Res.,88:639-643 1997
Okabe, S., Suganuma, M., Hayashi, M., Sueoka, E., Komori, A. and Fujiki, H.

Expression of the tumor necrosis factor α gene and early response genes by nodularin, a liver tumor promoter, in primary cultured rat hepatocytes
,J. Cancer Res. Clin. Oncol. ,123:413-419 1997
Sueoka, E., Sueoka, N., Okabe, S., Kozu, T., Komori, A., Ohta, T., Suganuma, M., Kim, S.-J., Lim, I. K. and Fujiki, H.

Isolation of dephosphonocalyculin A from the marine sponge, Discodermia calyx
,Tetrahed. Lett. ,38:3763-3764 1997
Matsunaga, S., Wakimoto, T., Fusetani, N. and Suganuma, M.

Carcinogenesis of microcystins
,(M-F. Watanabe, et al., eds), In: Toxic Microcystis, CRC Press, Inc.:203-232 1996
Fujiki, H., Sueoka, E. and Suganuma, M.

Naturally-derived tumor promoters and inhibitors of carcinogenesis
,J. Toxicol - Toxin Reviews, 15, Marcel Dekker, Inc.:129-156 1996
Fujiki, H. and Suganuma, M.

Expression of early response genes by nodularin, a new liver carcinogen, through inhibition of protein phosphatases 1 and 2A
,(T. Yasumoto, et al., eds), In: Harmful and Toxic Algal Blooms:483-486 1996
Sueoka, E., Sueoka, N., Komori, A., Okabe, S., Kozu, T., Suganuma, M. and Fujiki, H.

Superinduction of mouse epidermal ornithine decarboxylase activity by repeated 12-O tetradecanoylphorbol-13-acetate treatments
,Mol. Cell. Biochem. ,155:139-151 1996
Verma, A. K., Hsiao, K. M., Ahrens, H., Suganuma, M., Fujiki, H., Matsufuji, S. and Hayashi, H.

A new process of cancer prevention mediated through inhibition of tumor necrosis factor-α expressionA new process of cancer prevention mediated through inhibition of tumor necrosis factor-α expression
,Cancer Res.,56:3711-3715 1996
Suganuma, M., Okabe, S., Sueoka, E., Iida, N., Komori, A., Kim, S-J. and Fujiki, H.

Anti-tumor promoting activity of canventol and its synthetic analogs through inhibition of protein isoprenylation
,Jpn. J. Cancer Res. ,87:875-881 1996
Komori, A., Okabe, S., Suganuma, M., Kerr, M. A. Busch-Petersen, J., Oh, L. M., Zhuo, J., Kannangara, G. S. K., Zou, X., Tius, M. A. and Fujiki, H.

Inhibition of protein phosphatase 2A by cyclic peptides modelled on the microcystin ring
,BioMed. Chem. Lett.,6:2113-2116 1996
Quinn, R.J., Taylor, C., Suganuma, M. and Fujiki, H.

Japanese green tea as a cancer preventive in humans
,Nutrition Reviews,54:S67-S70 1996
Fujiki, H., Suganuma, M., Okabe, S., Komori, A., Sueoka, E., Sueoka, N., Kozu, T., and Sakai, Y.

Tumor promotion and prevention of stomach cancer
,(M., Nishi, et al.. eds), In:1st International Gastric Cancer Congress, Monduzzi Editore, Bologna:19-25 1995
Fujiki, H., Suganuma, M., Komori, A., Sueoka, E., Okabe, S., Sueoka, N., Aida, M., Kozu, T., Hamano, A., Sakai, Y. and Tatematsu, M.

Inhibition of N-methyl-N'-nitro-N-nitrosoguanidine-induced carcinogenesis by (-)-epigallocatechin gallate in the rat glandular stomach
,Cancer Res.,55:2081-2084 1995
Yamane, T., Takahashi, T., Kuwata, K., Oya, K., Inagake, M., Kitao, Y., Suganuma, M. and Fujiki, H.

Specific protein interacting with a tumor promoter, debromoaplysiatoxin, in bovine serum is alpha1-acid glycoprotein
, J. Cancer Res. Clin. Oncol. ,121:211-218 1995
Ueyama, H., Sasaki, I., Shimomura, K. and Suganuma, M.

Activation of protein kinase C by mycobacterial cord factor, trehalose 6-monomycolate, resulting in tumor necrosis factor-α release in mouse lung tissues
,Jpn. J. Cancer Res.,86:749-755 1995
Sueoka, E., Nishiwaki, S., Okabe, S., Iida, N., Suganuma, M., Yano, I., Aoki, K. and Fujiki, H.

Inhibition of PKC and PKA by chemopreventive organoselenium compounds
,Int. J. Oncol.,7:685-690 1995
Foiles, P. G., Fujiki, H., Suganuma, M., Okabe, S., Yatsunami, J., Miglietta, L. M., Upadhyaya, P., El-Bayoumy, K. and Ronai, Z.

Tautomycin: an inhibitor of protein phosphatases 1 and 2A but not a tumor promoter on mouse skin and rat glandular stomach
,J. Cancer Res. Clin. Oncol.,121:621-627 1995
Suganuma, M., Okabe, S., Sueoka, E., Nishiwaki, R., Komori, A., Uda, N., Isono, K. and Fujiki, H.

Novel monoclonal antibodies against microcystin and their protective activity for hepatotoxicity
,Natural Toxins,3:78-86 1995
Nagata, S., Saotome, H., Tsutsumi, T., Hasegawa, A., Sekijima, M., Harada, K-i., Suganuma, M. and Ueno, Y.

Expression of early response genes and of tumor necrosis factor-α gene by the okadaic acid class tumor promoters in relation to Carcinogenesis
,(Y. Hokama, P. et al., eds), In: Proceedings of International Symposium on Ciguatera and Marine Natural Products:183-195 1995
Sueoka, E., Suganuma, M., Okabe, S., Komori, A., Kozu, T., Ohta, T., Uemura, D. and Fujiki, H.

Agelasine, a new stimulator of protein phosphatase 2A
,(Y. Hokama, P. et al., eds), In: Proceedings of International Symposium on Ciguatera and Marine Natural Products:217-226 1995
Suganuma, M., Iguchi, T., Okabe, S., de Vries, D. J., Murphy, P. T., Baker J. T., Rao, K. S., Willis, R. H., Nakamura, H. and Fujiki, H.

Significance of marine toxins in tumor promotion of carcinogenesis
,(M. Eklund, et al., eds), In: Molecular Approaches to Food Safety Issues Involving Toxic Microorganisms:367-381 1995
Fujiki, H., Suganuma, M., Okabe, S., Komori, A., Sueoka, E., Kozu, T., Sueoka, N. and Morita, T.

Increase of labeling induces in gastrointestinal mucosae of mice and rats by compounds of the okadaic acid type
,J. Cancer Res. Clin. Oncol.,120:208-212 1994
Yuasa, H., Yoshida, K., Iwata, H., Nakanishi, H., Suganuma, M. and Tatematsu, M.

Inhibitory effects of (-)-epigallocatechin gallate on spontaneous hepatoma in C3H/HeNCrj mice and human hepatoma-derived PLC/PRF/5 cells
,Jpn. J. Cancer Res.,85:221-225 1994
Nishida, H., Omori, M., Fukutomi, Y., Ninomiya, M., Nishiwaki, S., Suganuma, M., Moriwaki, H. and Muto, Y.

Sarcophytol A: A new chemotherapeutic and chemopreventive agent for pancreatic cancer
,Pancreas,9:526-530 1994
Yokomatsu, H., Satake, K., Hiura, A., Tsutsumi, M. and Suganuma, M.

Two significant aspects of microcystin-LR: specific binding and liver specificity
,Cancer Lett.,83:283-289 1994
Nishiwaki, R., Ohta, T., Sueoka, E., Suganuma, M., Harada, K-i., Watanabe, M. F. and Fujiki, H.

Nodularin, a potent inhibitor of protein phosphatases 1 and 2A, is a new environmental carcinogen in male F344 rat liver
,Cancer Res.,54:6402-6406 1994
Ohta, T., Sueoka, E., Iida, N., Komori, A., Suganuma, M., Nishiwaki, R., Tatematsu, M., Kim, S-J., Carmichael, W. W. and Fujiki, H.

Tumor necrosis factor-alpha, a new tumor promoter, engendered by biochemical studies of okadaic acid
,J. Biochem.,115:1-5 1994
Fujiki, H. and Suganuma, M.

A new tumor promotion pathway and its inhibitors
,Cancer Detect. Prev. ,18:1-7 1994
Fujiki, H., Suganuma, M., Komori, A., Yatsunami, J., Okabe, S., Ohta, T. and Sueoka, E.

Tumor promotion by inhibitors of protein phosphatases 1 and 2A, the okadaic acid class of compounds
,In: Adv. Cancer Res.,61:143-194 1993
Fujiki, H. and Suganuma, M.

Mechanisms of action of new antitumor promoters
,(G. Bronzetti, H. Hayatsu, S. DeFlora, M. D. Waters, and D. M. Shankel eds), In: Antimutagenesis and Anticarcinogenesis Mechanisms III, Plenum Press, New York:317-323 1993
Suganuma, M., Yoshizawa, S., Yatsunami, J., Nishiwaki, S., Furuya, H., Okabe, S., Nishiwaki-Matsushima, R., Frenkel, K., Troll, W., Verma, A. K. and Fujiki, H.

Hyperphosphorylation of retinoblastoma protein and p53 by okadaic acid, a tumor promoter
,Cancer Res.,53: 239-241 1993
Yatsunami, J., Komori, A., Ohta, T., Suganuma, M. and Fujiki, H.

Absence of synergistic effects on tumor promotion in CD-1 mouse skin by simultaneous applications of two different types of tumor promoters, okadaic acid and teleocidin
,Cancer Res.,53:1012-1016 1993
Suganuma, M., Yatsunami, J., Yoshizawa, S., Okabe, S. and Fujiki, H.

Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation
,Cancer Res.,53:1982-1985 1993
Komori, A., Yatsunami, J., Suganuma, M., Okabe, S., Abe, S., Sakai, S., Sasaki, K. and Fujiki, H.

Anticarcinogenic activity of green tea polyphenols
,Jpn. J. Clin. Oncol.,23:186-190 1993
Komori, A., Yatsunami, J., Okabe, S., Abe, S., Hara, K., Suganuma, M., Kim, S-J. and Fujiki, H.

Canventol inhibits tumor promotion in CD-1 mouse skin through inhibition of tumor necrosis factor alpha release and of protein isoprenylation
,Cancer Res.,53:3462-3464 1993
Komori, A., Suganuma, M., Okabe, S., Zou, X., Tius, M. A. and Fujiki, H.

The conserved acid binding domain model of inhibitors of protein phosphatases 1 and 2A: Molecular modeling aspects
,BioMed. Chem. Lett.,6:1029-1034 1993
Quinn, R.J., Taylor, C., Suganuma, M. and Fujiki, H.

Significant marine natural products in cancer research
,Gazzetta Chimica Italiana,123:309-316 1993
Fujiki, H., Suganuma, M., Yatsunami, J., Komori, A., Okabe, S., Nishiwaki-Matsushima, R. and Ohta, T.

Okadaic acid is a potent angiogenesis inducer
,Jpn. J. Cancer Res.,83:6-9 1992
Oikawa, T., Suganuma, M., Ashinofuse, H. and Shimomura, M.

Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR
,J. Cancer Res. Clin. Oncol. ,118:420-424 1992
Nishiwaki-Matsushima, R., Ohta, T., Nishiwaki, S., Suganuma, M., Kohyama, K., Ishikawa, T., Carmichael, W. W. and Fujiki, H.

Structurally different members of the okadaic acid class selectively inhibit protein serine/ threonine but not tyrosine phosphatase activity
,Toxicon,30:873-878 1992
Suganuma, M., Fujiki, H., Okabe, S., Nishiwaki, S., Brautigan, D., Ingebritsen, T. S. and Rosner, M. R.

Anticarcinogenic effects of (-)-epigallocatechin gallate
,Prev. Med.,21:503-509 1992
Fujiki, H., Yoshizawa, S., Horiuchi, T., Suganuma, M., Yatsunami, J., Nishiwaki, S., Okabe, S., Nishiwaki-Matsushima, R., Okuda, T. and Sugimura, T.

An alternative theory of tissue specificity by tumor promotion of okadaic acid in glandular stomach of SD rats
,Carcinogenesis,13:1841-1845 1992
Suganuma, M., Tatematsu, M., Yatsunami, J., Yoshizawa, S., Okabe, S., Uemura, D. and Fujiki, H.

Hyperphosphorylation of cytokeratins 8 and 18 by microcystin-LR, a new liver tumor promoter, in primary cultured rat hepatocytes
,Carcinogenesis ,13:2443-2447 1992
Ohta, T., Nishiwaki, R., Yatsunami, J., Komori, S., Suganuma, M. and Fujiki, H.

Specific mechanistic aspects of animal tumor promoters: The okadaic acid pathway
, (R. D'Amato, et al.. eds), In: Relevance of Animal Studies to the Evaluation of Human Cancer Risk, Wiley-Liss, Inc.:337-350 1992
Fujiki, H., Suganuma, M., Nishiwaki, S., Yoshizawa, S.,Yatsunami, J., Matsushima, R., Furuya, H., Okabe, S., Matsunaga, S. and Sugimura, T.

Marine natural products against tumor development
,(T. Kobayashi ed), In: Proceedings of the 1st International Congress on Vitamins and Biofactors in Life Science:333-336 1992
Yatsunami, J., Fujiki, H., Komori, A., Suganuma, M., Nishiwaki, S., Okabe, S., Nishiwaki- Matsushima, R., Ohta, T., Matsunaga, S., Fusetani, N. and Sugimura, T.

Sarcophytol A and (-)-epigallocatechin gallate (EGCG), nontoxic inhibitors of cancer development
,(L. Wattenberg, et al., eds), In: Cancer Chemoprevention, CRC Press:393-405 1992
Fujiki, H., Suganuma, M., Yoshizawa, S., Yatsunami, J., Nishiwaki, S., Furuya, H., Okabe, S., Nishiwaki-Matsushima, R., Matsunaga, S., Muto, Y., Okuda, T. and Sugimura, T.

Signal transduction by the indole-containing tumor promoters, the teleocidin class
, (I. Ishiguro, et al., eds), In: Advances in Tryptophan Research 1992 Fujita Health University Press, Toyoake:191-194 1992
Fujiki, H., Suganuma, M., Yatsunami, J., Komori, A., Okabe, S., Nishiwaki, S., Nishiwaki- Matsushima, R. and Ohta, T.

Involvement of protein phosphatases in carcinogenesis
,(K. Miyai, et al., eds), In: Progress in Clinical Biochemistry Elsevier Science Publishers B. V.:701-703 1992
Nishiwaki, S., Fujiki, H., Suganuma, M., Yoshizawa, S., Yatsunami, J., Komori, A., Okabe, S., Nishiwaki-Matsushima, R., Ohta, T. and Sugimura, T.

Penta-O-galloyl-B-D-glucose and (-)-epigallocatechin gallate, Cancer Preventive Agents
,(M.-T. Huang, et al., eds), In: ACS Symposium Series "Phenolic Compounds in Food and Their Effects on Health II", American Chemical Society, Washington, DC.:316-325 1992
Yoshizawa, S., Horiuchi, T., Suganuma, M., Nishiwaki, S., Yatsunami, J., Okabe, S., Okuda, T., Muto, Y., Frenkel, K., Troll, W. and Fujiki, H.

Sarcophytol A and its analogs, cancer preventive activity
,(M-T. Huang, et al., eds), In: ACS Symposium Series "Phenolic Compounds in Food and their Effects on Health II", American Chemical Society, Washington, DC.:380-387 1992
Fujiki, H., Suganuma, M., Takagi, K., Nishiwaki, S., Yoshizawa, S., Okabe, S., Yatsunami, J., Frenkel, K., Troll, W., Marshall, J. A. and Tius, D.

Differential effects of cryptoporic acids D and E, inhibitors of superoxide anion radical release, on tumor promotion of okadaic acid in mouse skin
,Carcinogenesis ,17:1129-1131 1991
Matsunaga, S., Furuya-Suguri, H., Nishiwaki, S., Yoshizawa, S., Suganuma, M., Hashimoto, T., Asakawa, Y. and Fujiki, H.

Pendolmycin, a new tumor promoter of the teleocidin A class on skin of CD-1 mice
,Jpn. J. Cancer Res.,82: 779-783 1991
Nishiwaki, S., Fujiki, H., Yoshizawa, S., Suganuma, M., Furuya-Suguri, H., Okabe, S., Nakayasu, M., Okabe, K., Muratake, H., Natsume, M., Umezawa, K., Sakai, S. and Sugimura, T.

Vimentin is hyperphosphorylated in primary human fibroblasts treated with okadaic acid
,Biochem. Biophys. Res. Commun.,177:1165-1170 1991
Yatsunami, J., Fujiki, H., Suganuma, M., Yoshizawa, S., Eriksson, J. E., Olson, M. O. J. and Goldman, R. D.

Structure-function relationships of microcystins, liver tumor promoters, in interaction with protein phosphatase
,Jpn. J. Cancer Res.,82: 993-996 1991
Nishiwaki-Matsushima, R., Nishiwaki, S., Ohta, T., Yoshizawa, S., Suganuma, M., Harada, K., Watanabe, M. F. and Fujiki, H.

Binding competition of okadaic acid derivatives to anti-okadaic acid antibody
,Toxicon.,29:1409-1412 1991
Yatsunami, J., Fujiki, H., Suganuma, M., Nishiwaki, S., Ojika, M., Yamada, K. and Levine, L.

Inhibitory effect of sarcophytol A on development of spontaneous hepatomas in mice
,Jpn. J. Cancer Res.,82:1234-1238 1991
Yamauchi, O., Omori, M., Ninomiya, M., Okuno, M., Moriwaki, H., Suganuma, M., Fujiki, H. and Muto, Y.

Tumor promoters and anti-tumor promoters
,(Thai Environmental Mutagen Society ed), In: Environmental Mutagens, Carcinogens and Teratogens: Principles and Short-term Assays:209-230 1991
Fujiki, H., Suganuma, M., Suguri, H., Yoshizawa, S., Takagi, K., Hirota, M., Sassa, T., Richter, W. W., Uda, N., Suttajit, M., Wongchai, V. and Sugimura, T.

Mechanisms of action of okadaic acid class tumor promoters on mouse skin
,In: Environmental Health Perspectives,93:211-214 1991
Fujiki, H., Suganuma, M., Yoshizawa, S., Nishiwaki, S., Winyar, B. and Sugimura, T.

Tumor antipromoters: sarcophytols A and B, (-)-epigallocatechin gallate (EGCG), and morusin
,(O. F. Nygaard and A. C. Upton eds), In: Anticarcinogenesis and Radiation Protection 2, Plenum Press, New York:357-362 1991
Fujiki, H., Suganuma, M., Yoshizawa, S., Nishiwaki, S., Kobayashi, M., Okuda, T., Nomura, T. and Sugimura, T.

Calyculin A, an inhibitor of protein phosphatases, a potent tumor promoter on CD-1 mouse skin
,Cancer Res. ,50:3521-3525 1990
Suganuma, M., Fujiki. H., Furuya-Suguri, H., Yoshizawa, S., Yasumoto, S., Kato, Y., Fusetani, N. and Sugimura, T.

Tumor-promoting activity of staurosporine, a protein kinase inhibitor on mouse skin
,Cancer Res.,50:4974-4978 1990
Yoshizawa, S., Fujiki, H., Suguri, H., Suganuma, M., Nakayasu, M., Matsushima, R. and Sugimura, T.

Photoaffinity labeling of protein phosphatase 2A, the receptor for a tumor promoter okadaic acid, by [27-3H]-methyl 7-O-(4-azidobenzoyl)okadaate
,Biochem. Biophys. Res. Commun.,170:1359-1364 1990
Nishiwaki, S., Fujiki, H., Suganuma, M., Ojika, M., Yamada, K. and Sugimura, T.

Structure-activity relationship within a series of okadaic acid derivatives
,Carcinogenesis,11:1837-1841 1990
Nishiwaki, S., Fujiki, H., Suganuma, M., Furuya-Suguri, H., Matsushima, R., Iida, Y., Ojika, M., Yamada, K., Uemura, D., Yasumoto, T., Schmitz, F. J. and Sugimura, T.

Lyngbyatoxins B and C, two new irritants from Lyngbya majuscula
,J. Nat. Prod. ,53:1593-1596 1990
Aimi, N., Odaka, H., Sakai, S., Fujiki, H., Suganuma, M., Moore, R. E. and Patterson, G. M. L.

New tumor promoters from marine natural products
,(S. Hall and G. Strichartz eds), In: ACS Symposium Series 418, "Marine Toxins: Origins, Structure and Molecular Pharmacology", American Chemical Society, Washington, DC:232-240 1990
Fujiki, H., Suganuma, M., Suguri, H., Yoshizawa, S., Takagi, K., Nakayasu, M., Ojika, M., Yamada, K., Yasumoto, T., Moore, R. E. and Sugimura, T.

New anti-tumor promoters: (-)-epigallocatechin gallate and sarcophytols A and B
,(Y. Kuroda et al., eds), In: Antimutagenesis and Anticarcinogenesis Mechanisms II, Plenum Press, N. Y.:205-212 1990
Fujiki, H., Suganuma, M., Suguri, H., Takagi, K., Yoshizawa, S., Ootsuyama, A., Tanooka, H., Okuda, T., Kobayashi, M. and Sugimura, T.

New anti-promoters, the constituents of Japanese green tea
,(R. Sasaki, and K. Aoki eds), In: Epidemiology & Prevention of Cancer, The University of Nagoya Press:36-41 1990
Fujiki, H., Suganuma, M., Yoshizawa, S., Nishiwaki, S., Yoshizawa, S., Okuda, T. and Sugimura, T.

A new pathway of tumor promotion by the okadaic acid class compounds
,(Y. Nishizuka et al., eds), In: The Biology and Medicine of Signal Transduction, Raven Press, New York:340-344 1990
Fujiki, H., Suganuma, M., Nishiwaki, S., Yoshizawa, S., Winyar, B., Sugimura, T. and Schmitz, F. J.

Sarcophytols A and B inhibit tumor promotion by teleocidin in two-stage carcinogenesis in mouse skin
,J. Cancer Res. Clin. Oncol.,115: 25-28 1989
Fujiki, H., Suganuma, M., Suguri, H., Yoshizawa, S., Takagi, K. and Kobayashi, M.

Apparent "activation" of protein kinases by okadaic acid class tumor promoters
,Biochem. Biophys. Res. Commun.,159:939-944 1989
Sassa, T., Richter, W. W., Uda, N., Suganuma, M., Suguri, H., Yoshizawa, S., Hirota, M. and Fujiki, H.

Specific binding of okadaic acid, a new tumor promoter in mouse skin
,FEBS Lett.,250:615-618 1989
Suganuma, M., Suttajit, M., Suguri, H., Ojika, M., Yamada, K. and Fujiki, H.

Morusin, isolated from root bark of Morus alba. L., inhibits tumor promotion of teleocidin
,Phytotherapy Res.,3:193-195 1989
Yoshizawa, S., Suganuma, M., Fujiki, H., Fukai, T., Nomura, T. and Sugimura, T.

Codon 61 mutations in the c-Harvey-ras gene in mouse skin tumors induced by 7,12 dimethylbenz(a)anthracene plus okadaic acid class tumor promoters
,Mol. Carcinogenesis,2:184-187 1989
Fujiki, H., Suganuma, M., Yoshizawa, S., Kanazawa, H., Sugimura, T., Manam, S., Kahn, S. M., Jiang, W., Hoshina, S. and Weinstein, I. B.

Diversity in chemical nature and mechanism of response to tumor promoters
,In: Skin Carcinogenesis: Mechanisms and Human Relevance, Alan R. Liss, Inc.:281-291 1989
Fujiki, H., Suganuma, M., Suguri, H., Yoshizawa, S., Hirota, M., Takagi, K. and Sugimura, T.

New tumor promoters from marine sources: The okadaic acid class
, (S. Natori, et al., eds), In: Mycotoxins and Phycotoxins '88, Elsevier, Science Publishers B. V., Amsterdam:453-460 1989
Fujiki, H., Suganuma, M., Suguri, H., Yoshizawa, S., Takagi, K., Sassa, T., Uda, N., Wakamatsu, K., Yamada, Y., Yasumoto, T., Kato, Y., Fusetani, N., Hashimoto, K. and Sugimura, T.

Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter
,Proc. Natl. Acad. Sci. USA,85:1768-1771 1988
Suganuma, M., Fujiki, H., Suguri, H., Yoshizawa, S., Hirota, M., Nakayasu, M., Ojika, M., Wakamatsu, K., Yamada, K. and Sugimura, T.

Inhibition of ornithine decarboxylase induction by retinobenzoic acids in relation to their binding affinities to cellular retinoid-binding proteins
,J. Cancer Res. Clin. Oncol.,114: 221-224 1988
Takagi, K., Suganuma, M., Kagechika, H., Shudo, K., Ninomiya, M., Muto, Y. and Fujiki, H.

Specific binding of [3H]retinoids to cellular retinoid-binding proteins
,FEBS Lett.,233:255-258 1988
Ninomiya, M., Suganuma, M., Paik, N. S., Muto, Y. and Fujiki, H.

Similar, potent tumor-promoting activity of all isomers of teleocidins A and B in two-stage carcinogenesis experiment on the skin of CD-1 mice
,Cancer Res.,48:4211-4214 1988
Fujiki, H., Suganuma, M., Ninomiya, M., Yoshizawa, S., Yamashita, K., Takayama, S., Hitotsuyanagi, Y., Sakai, S., Shudo, K. and Sugimura, T.

Diarrhetic shellfish toxin, dinophysistoxin-1, is a potent tumor promoter on mouse skin
,Jpn. J. Cancer Res. (Gann),79:1089-1093 1988
Fujiki, H., Suganuma, M., Suguri, H., Yoshizawa, S., Takagi, K., Uda, N., Wakamatsu, K., Yamada, K., Murata, M., Yasumoto, T. and Sugimura, T.

Chemistry and anti-tumor promoting activity of Morus flavonoids
,In: Plant Flavonoids in Biology and Medicine II: Biochemical, Cellular and Medicinal Properties, Alan R. Liss, Inc.:267-281 1988
Nomura, T., Fukai, T., Hano, Y., Yoshizawa, S., Suganuma, M. and Fujiki, H.

Tumor promoting activity of teleocidin in skin and forestomach of mice initiated transplacentally with 7,12-dimethylbenz(a)anthracene
,J. Cancer Res. Clin. Oncol.,113:123-125 1987
Suganuma, M., Fujiki, H., Morino, K., Takayama, S. and Sugimura, T.

Synthetic analogues (indolactams) of (-)-indolactam-V are new congeners of the teleocidin class of tumor promoters
,Jpn. J. Cancer Res. (Gann),78:577-582 1987
Hirota M., Suganuma, M., Yoshizawa, S., Horiuchi, T., Nakayasu, M. Hasegawa, M., Endo, Y., Shudo, K. and Fujiki, H.

Resistance of human bronchial epithelial cells to teleocidin in a two-stage carcinogenesis experiment
,Acta Pathol. Jpn. ,37:1859-1865 1987
Teshima, S., Shimosato, Y., Kodama, T., Koide, T., Suganuma, M. and Fujiki, H.

Environmental aspects of new tumor promoters as human risk factors
,In: Current Status of Cancer Research in Asia, the Middle East and Other Countries:215-226 1987
Fujiki, H., Suganuma, M., Hirota, M., Yoshizawa, S., Suguri, H., Suttajit, M., Wongchai, V. and Sugimura, T.

Induction of ornithine decarboxylase activity in mouse skin by a possible tumor promoter, okadaic acid
,Proc. Japan Acad.,63(B):51-53 1987
Fujiki, H., Suganuma, M., Suguri, H., Yoshizawa, S., Ojika, M., Wakamatsu, K., Yamada, K. and Sugimura, T.

Presence of tumor promoters in the seed oil of Jatropha curcas L. from Thailand
,Jpn. J. Cancer Res. (Gann),78:223-226 1987
Horiuchi, T., Fujiki, H., Hirota, M., Suttajit, M., Suganuma, M., Yoshioka, A., Wongchai, V., Hecker, E. and Sugimura, T.

Inhibition of tumor promotion by flavonoids, In: Plant Flavonoids in Biology and Medicine
,Biochemical, Pharmacological, and Structure Activity Relationships, Alan R. Liss, Inc.,213:429-440 1986
Fujiki, H., Horiuchi, T., Yamashita, K., Hakii, H., Suganuma, M., Nishino, H., Iwashima, A., Hirata, Y. and Sugimura T.

Des-O-methylolivoretin C is a new member of the teleocidin class of tumor promoters
,Jpn. J. Cancer Res. (Gann),77:222-225 1986
Ninomiya, M., Fujiki, H., Paik, N. S., Hakii, H., Suganuma, M., Hitotsuyanagi, Y., Aimi, N., Sakai, S., Endo, Y., Shudo, K. and Sugimura, T.

Binding studies of [3H]lyngbyatoxin A and [3H]debromoaplysiatoxin to the phorbol ester receptor in a mouse epidermal particulate fraction
,Carcinogenesis,7:641-644 1986
Moore, R. E., Patterson, G. M. L., Entzeroth, M., Morimoto, H., Suganuma, M., Hakii, H., Fujiki, H. and Sugimura, T.

Palytoxin is a non-12-O-tetradecanoylphorbol-13-acetate type tumor promoter in two-stage mouse skin carcinogenesis
,Carcinogenesis,7: 707-710 1986
Fujiki, H., Suganuma, M., Nakayasu, M., Hakii, H., Horiuchi, T., Takayama, S. and Sugimura, T.

Modulation of phorbol ester receptors in mouse skin by application of quercetin
,Jpn. J. Cancer Res. (Gann),77:526-531 1986
Horiuchi, T., Fujiki, H., Hakii, H., Suganuma, M., Yamashita, K. and Sugimura, T.

Synergistic stimulation of histamine release from rat peritoneal mast cells by (TPA) 12-O tetradecanoylphorbol-13-acetate-type tumor promoters and non-TPA-type tumor promoters
,Biochim. Biophys. Acta,887:94-99 1986
Ohuchi, K., Hirasawa, N., Takahashi, C., Watanabe, M., Tsurufuji, S., Fujiki, H., Suganuma, M., Hakii, H., Sugimura, T. and Christensen, S. B.

Involvement of sulfatide in activation of protein kinase C by tumor promoters
,Biochem. Biophys. Res. Commun.,138:153-158 1986
Fujiki, H., Yamashita, K., Suganuma, M., Taniguchi, N. and Makita, A.

Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanoylphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis
,J. Cancer Res. Clin. Oncol.,111:177-181 1986
Hakii, H., Fujiki, H., Suganuma, M., Nakayasu, M., Tahira, T., Sugimura, T., Scheuer, P. J. and Christensen, S. B.

Absolute configuration of lyngbyatoxin A (teleocidin A-1) and teleocidin A-2
,Tetrahedron Lett.,27:5219-5220 1986
Sakai, S., Hitotsuyanagi, Y., Aimi, N., Fujiki, H., Suganuma, M., Sugimura, T., Endo, Y. and Shudo, K.

The structures of additional teleocidin class tumor promoters
,Chem. Pharm. Bull.,34:4883-4886 1986
Sakai, S., Hitotsuyanagi, Y., Yamaguchi, K., Aimi, N., Ogata, K., Kuramochi, T., Seki, H., Hara, R., Fujiki, H., Suganuma, M., Sugimura, T., Endo, Y., Shudo, K. and Koyama, Y.

Tumor promoting activities of new synthetic analogues of teleocidin
,Proc. Japan. Acad.,61:45-47 1985
Fujiki, H., Suganuma, M., Hakii, H., Nakayasu, M., Endo, Y., Shudo, K., Irie, K., Koshimizu, K. and Sugimura, T.

Stimulation of prostaglandin E2 production by 12-O-tetradecanoylphorbol-13-acetate (TPA) type and non-TPA-type tumor promoters in macrophages and its inhibition by cycloheximide
,Biochim. Biophys. Acta ,834:42-47 1985
Ohuchi, K., Watanabe, M., Yoshizawa, K., Tsurufuji, S., Fujiki, H., Suganuma, M., Sugimura, T. and Levine, L.

A blue-green alga from Okinawa contains aplysiatoxins, the third class of tumor promoters
,Jpn. J. Cancer Res. (Gann),76:257-259 1985
Fujiki, H., Ikegami, K., Hakii, H., Suganuma, M., Yamaizumi, Z., Yamazato, K., Moore, R. E. and Sugimura, T.

New biological significance of indole-containing compounds as initiators or tumor promoters in chemical carcinogenesis
, (H. G. Schlossberger et al., eds), In: Progress in Tryptophan and Serotonin Research, Walter de Gruyter & Co., Berlin, New York:793-802 1984
Fujiki, H., Suganuma, M., Tahira, T., Esumi, M., Nagao, M., Wakabayashi, K. and Sugimura, T.

New classes of tumor promoters: teleocidin, aplysiatoxin, and palytoxin
,(H. Fujiki, et al.. eds), In: Cellular Interactions By Environmental Tumor Promoters, Jpn. Sci. Soc. Press, Tokyo/VNU Science Press, Utrecht:37-45 1984
Fujiki, H., Suganuma, M., Tahira, T., Yoshioka, A., Nakayasu, M., Endo, Y., Shudo, K., Takayama, S., Moore R. E. and Sugimura, T.

Estimation of tumor promoting activity and structure-function relationships of aplysiatoxins
,Carcinogenesis,5:315-318 1984
Suganuma, M., Fujiki, H., Tahira, T., Cheuk, Ch., Moore, R. E. and Sugimura, T.

A two-stage mouse skin carcinogenesis study of lyngbyatoxin A
,J. Cancer Res. and Clin. Oncol.,108:174-176 1984
Fujiki, H., Suganuma, M., Hakii, H., Bartolini, G., Moore. R. E., Takayama, S. and Sugimura, T.

Studies on olivoretins indicate a requirement for a free hydroxyl group for teleocidin B activity
,Gann ,75:837-840 1984
Horiuchi, T., Fujiki, H., Suganuma, M., Hakii, H., Nakayasu, M. Hitotsuyanagi, Y., Aimi, N., Sakai, S., Endo, Y., Shudo, K. and Sugimura, T.

Structure-activity studies on synthetic analogues (indolactams) of the tumor promoter teleocidin
,Gann,75:866-870 1984
Fujiki, H., Suganuma, M., Nakayasu, M., Tahira, T., Endo, Y., Shudo, K. and Sugimura, T.

Reduction by N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), a calmodulin antagonist, in the number of phorbol ester receptors in mouse skin
,Biochem. Biophys. Res. Commun.,124:726-730 1984
Nishino, H., Fujiki, H., Suganuma, M., Horiuchi, T., Iwashima, A. and Sugimura, T.

Isolation and structure elucidation of teleocidin B-1, B-2, B-3, and B-4
,Chem. Pharm. Bull.,32:4233-4236 1984
Hitotsuyanagi, Y., Fujiki, H., Suganuma, M., Aimi, N., Sakai, S., Endo, Y., Shudo, K., and Sugimura, T.

Delayed induction of ornithine decarboxylase in mouse skin after irradiation with beta-rays
,Cancer Lett.,15:15-17 1982
Fujiki, H., Mori, M. and Tanooka, H.

Teleocidin: New naturally occurring tumor promoter
,(E. Hecker et al. eds.), In: Carcinogenesis-A Comprehensive Survey7, Raven Press, New York:69-73 1982
Sugimura, T., Fujiki, H., Mori, M., Nakayasu, M., Terada, M., Umezawa, K. and Moore, R. E.

The third class of new tumor promoters, polyacetates (debromoaplysiatoxin and aplysiatoxin), can differentiate biological actions relevant to tumor promoters
,Gann,73:495-497 1982
Fujiki, H., Suganuma, M., Nakayasu, M., Hoshino, H., Moore, R. E. and Sugimura, T.

Relation between the structures of ingenol esters and their ornithine decarboxylase-inducing activities in mouse skin
,(E. Hecker et al., eds.), In: Carcinogenesis-A Comprehensive Survey7, Raven Press, New York:65-67 1982
Fujiki, H., Mori, M., Sugimura, T., Ohigashi, H., Hirota, M. and Koshimizu, K.

Teleocidin from Streptomyces is a potent promoter of mouse skin carcinogenesis
,Carcinogenesis,3:895-898 1982
Fujiki, H., Suganuma, M., Matsukura, N., Sugimura, T. and Takayama, S.

Existence of an optimal dose of dihydroteleocidin B for skin tumor promotion
,Gann,73:531-533 1982
Suganuma, M., Fujiki, H. and Sugimura, T.

Resiniferonol-related diterpene esters from Daphne odora Thunb. and their ornithine decarboxylase-inducing activity in mouse skin
,Agric. Biol. Chem.,46:2605-2608 1982
Ohigashi, H., Hirota, M., Ohtsuka, T., Koshimizu, K., Fujiki, H., Suganuma, M., Yamaizumi, Z. and Sugimura, T.

Teleocidin, lyngbyatoxin A and their hydrogenated derivatives, possible tumor promoters, induce terminal differentiation in HL-60 cells
,Cancer Lett.,12:271-277 1981
Nakayasu, M., Fujiki, H., Mori, M. and Sugimura, T.

Indole alkaloids: dihydroteleocidin B, teleocidin, and lyngbyatoxin A as members of a new class of tumor promoters
,Proc. Natl. Acad. Sci. USA,78:3872-3876 1981
Fujiki, H., Mori, M., Nakayasu, M., Terada, M., Sugimura, T. and Moore, R. E.

Stimulation of prostaglandin production and choline turnover in HeLa cells by lyngbyatoxin A and dihydroteleocidin B
,Biochem. Biophys. Res. Commun.,102:100-107 1981
Sakamoto, H., Terada, M., Fujiki, H., Mori, M., Nakayasu, M., Sugimura, T. and Weinstein I. B.

Relationship between ornithine decarboxylase-inducing activity and configuration at C-4 in phorbol ester derivatives
,J. Cancer Res. Clin. Oncol.,98:9-13 1980
Fujiki, H., Mori, M., Sugimura, T., Hirota, M., Ohigashi, H. and Koshimizu, K.

A possible naturally occurring tumor promoter, teleocidin B from Streptomyces
,Biochem. Biophys. Res. Commun.,90:976-983 1979
Fujiki, H., Mori, M., Nakayasu, M., Terada, M. and Sugimura, T.

Phosphoethanolamine as a growth factor of a mammary carcinoma cell line of rat
,Proc. Natl. Acad. Sci. USA,76:5741-5744 1979
Kano-Sueoka, T., Cohen, D. M., Yamaizumi, Z., Nishimura, S., Mori, M. and Fujiki, H.

Rapid purification of protein phosphatase 2A from mouse brain by microcystin-affinity chromatography
,FEBS Lett.,279(1991):115-118
Nishiwaki, S., Fujiki, H., Suganuma, M., Nishiwaki-Matsushima, R. and Sugimura T.

学会発表
Innovative strategy of cancer treatment with the combination of Am80, a potent synthetic retinoid, and green tea catechin via down-regulation of histone deacetylase 4, -5, and -6
生体医歯工学共同研究拠点国際シンポジウム 201611
Rawangkan, A., Oya, Y., Iida, K., Kagechika, H., Shido, K., Fujiki, H., Suganuma, M.

New mechanism of synergistic anti-cancer activity using the combination of Am80 and green tea catechin: Down-regulation of histone deacetylase 4, -5, and -6
日本レチノイド研究会,日本レチノイド研究会 第27回学術集会講演要旨集:29 201610
Rawangkan Anchalee

AXL, receptor tyrosine kinase, induces metastatic phenotypes in non-small cell lung cancer cells by reducing stiffness
75h Annual Meeting of the Japanese Cancer Association,75h Annual Meeting of the Japanese Cancer Association:248 201610
Iida, K., Sakai, R., Umsumarng, S., Rawangkan, A., Suganuma, M.

EGCG enhances anti-tumor immune response via inhibition of PD-L1 expression
75h Annual Meeting of the Japanese Cancer Association,75h Annual Meeting of the Japanese Cancer Association:220 201610
Rawangkan, A., Iida, K., Sakai, R., Fujiki, H., Suganuma, M.

Chemo-modulatory effect of stemofoline against human multidrug resistant leukemic cells in animal model
75h Annual Meeting of the Japanese Cancer Association:254 201610
Umsumarng, S., Iida, K., Oya, Y., Sakai, R., Rawangkan, A., Kobayashi, Y., Pitchakarn, P., Yodkeeree, S., Mapoung, S., Suganuma, M., Limtrakul, P.

BTG2 gene down-regulates nucleolin, Tipα-receptor, resulting in suppression of H. pylori-gastric cancer microenvironment
75h Annual Meeting of the Japanese Cancer Association,75h Annual Meeting of the Japanese Cancer Association:154 201610
Suganuma, M., Oya, Y., Umsumarng, S., Watanabe, T., Iida, K., Rawangkan, A., Kobayashi, Y., Shimizu, Y., Devanand, P., Fujiki, H., Lim.., I. K.

緑茶カテキンの細胞硬化を介した転移抑制機構における受容体型チロシンキナーゼAXL抑制の重要性
第89回生化学会,第89回日本生化学会大会プログラム集:81 201609
酒井瞭、飯田圭介、Rawangkan, A.,菅沼雅美

サイズ分画による乳癌抹消血循環腫瘍細胞の分離および解析
第24回日本乳癌学会学術総会 201606
永井成勲、戸塚勝理、高井健、小松恵、林祐二、久保和之、黒住献、松本広志、井上賢一、菅沼雅美

Innovative cancer treatment of human lung cancer cells PC-9 with a synthetic retinoid Am80 and EGCG via inhibition of HDAC4 and HDAC5
アメリカ癌学会,Annual Meeting of AACR 201604
Masami Suganuma

The reseptor tyrosine kinase, AXL, regulates metastatic potential by changing biomechanical properties of non-small lung cancer cell lines
The 13th Korea-Japan Joint Symposium on Cancer and Aging Research,The 13th Korea-Japan Joint Symposium on Cancer and Aging Research:49 201602
Iida, K., Sakai, R.,Oya, Y., Umsumarng, S., Rawangkan, A., Suganuma, M.

BTG2/TIS21 gene induces down-regulation of nucleolin in gastric cancer cells, resulting in suppression of Tipa activity, an oncoprotein of H. pylori
The 13th Korea-Japan Joint Symposium on Cancer and Aging Research,The 13th Korea-Japan Joint Symposium on Cancer and Aging Research:53 201602
Oya, Y., Devanand, P., Kobayashi, Y., Shimizu, Y., Fujiki, H., Suganuma, M., Lim, I.K.

Combination of EGCG and Am80 is an innovative cancer treatment mediated through induction of GADD153 and DR5 gene expressions caused by inhibition of histone deacetylase 4
The 3rd International Conference on Retinoids,The 3rd International Conference on Retinoids:75 201510
Oya, Y., Suganuma, M., Iida, K., Sakai, R., Kagechika, H., Shudo, K., Fujiki, H.

チロシンキナーゼレセプターAXLの活性化がヒト非小細胞肺がんの細胞弾性を低下させ、転移能を促進する
The 74h Annual Meeting of the Japanese Cancer Association,The 74h Annual Meeting of the Japanese Cancer Association 201510
Iida, K., Sakai, R.,Oya, Y., Watanabe, T., Fujiki, H.Suganuma, M.,

EGCGと合成レチノイドAm80との併用によるHDAC4とHDAC5の抑制はがん治療効果の亢進において重要な役割をする
The 74h Annual Meeting of the Japanese Cancer Association,The 74h Annual Meeting of the Japanese Cancer Association 201510
Suganuma, M., Oya, Y., Iida, K., Sakai, R., Kagechika, H., Shudo, K., Fujiki, H.

がん抑制遺伝子TIS21によるピロリ菌の発がん因子Tipαの活性阻害
The 74h Annual Meeting of the Japanese Cancer Association,The 74h Annual Meeting of the Japanese Cancer Association 201510
Oya, Y., Devanand, P.,  Iida, K., Sakai, R., Kobayashi, Y., Shimizu, Y., Fujiki, H., Lim, I.K., Suganuma, M.

Low cell stiffness is characteristic of highly metastatic non-small cell lung cancer cells
The 6th Annual Symposium "Physics of Cancer", The 6th Annual Symposium Physics of Cancer:36 201509
Suganuma, M

Higher cell stiffness as a key mechanical phenotype for inhibition of metastasis of cancer
International Symposium on Nanoarchitectonics for Mechanobiology ,International Symposium on Nanoarchitectonics for Mechanobiology :32 201507
Suganuma, M

Increase of cell stiffness and rigid elasticity of cell membrane as new preventive parameters of cancer progression with EGCG
International Conference on the 19th Annual Meeting of Korean Society of Cancer Prevention,International Conference on the 19th Annual Meeting of Korean Society of Cancer Prevention 201412
Sugamuma, M., Watanabe, T., Anupom, M., Fujiki, H.

Primary cancer prevention by green tea and tertiary cancer prevention by the combination of green tea catechins and anticancer drugs
International Conference on the 19th Annual Meeting of Korean Society of Cancer Prevention,International Conference on the 19th Annual Meeting of Korean Society of Cancer Prevention 201412
Fujiki, H., Sueoka, E., Suganuma, M.

EMT associated with lower cell stiffiness and metastatic activity in lung cancer cell lines
The 73rd Annual Meeting of the Japanese Cancer Association ,The 73rd Annual Meeting of the Japanese Cancer Association :204 201409
Suganuma, M., Li, Z., Anupom, M., Takahashi, A., Watanabe, T., Oya, Y., Fujiki, H.,

Significant roles of surface nucleolin in ERK and NF-κB activation induced by Tipα, a carcinogenic factor of H. pylori
The 73rd Annual Meeting of the Japanese Cancer Association ,The 73rd Annual Meeting of the Japanese Cancer Association :63 201409
Watanabe, T., Oya, Y., Anupom, M., Li, Z., Yamaguchi, K., Sueoka, E., Fujiki, H., Suganuma, M.

Indauction of GADD153-DR5 apoptotic pathway by combination of EGCG and Am80 in human lung cancer cells
The 73rd Annual Meeting of the Japanese Cancer Association ,The 73rd Annual Meeting of the Japanese Cancer Association 201409
Anupom, M., Oya, Y.,Watanabe, T., Fujiki, H., Kagechika, H., Syudou, K., Suganuma, M.

Lower cell stiffness as a significant phenotype of epithelial-mesenchymal transition (EMT)in cancer progression
The 12th Japan-Korea Joint Symposium on Cancer and Aging Research, The 12th Japan-Korea Joint Symposium on Cancer and Aging Research:76 201406
Suganuma, M., Li, Z., Takahashi, A., Watanabe, T., Oya, Y., Suzuki, K., Kanno, M., Fujiki, H.

Synaegistic induction of apoptosis by inhibition of histone deacetylase 6 (HDAC6) in human lung cancer cells treated with combination of EGCG and Am80
The 12th Japan-Korea Joint Symposium on Cancer and Aging Research ,The 12th Japan-Korea Joint Symposium on Cancer and Aging Research :60 201406
Anupom, M., Oya, Y., Watanabe, T., Suzuki, K., Kanno, M., Li, Z., Fujiki, H., Kagechika, H., Shudo, K., Y., Suganuma, M.

Epithelial-mesenchymal transition induced by TNF-α inducing protein of Helicobacter pylori through binding to cell-surface nucleolin
The 12th Japan-Korea Joint Symposium on Cancer and Aging Research,The 12th Japan-Korea Joint Symposium on Cancer and Aging Research:64 201406
Watanabe, T., Anupom, M., Suzuki, K., Kurusu-Kanno, M., Li, Z., Fujiki, H., Suganuma, M.

Cell stiffess as a new incicator of diagnosis for human lung cancer cells and their metastasis
The 104th Annual Meeting of American Association for Cancer Research 201404
Suganuma, M.

肺がん細胞の運動能および転移能の指標となる細胞弾性
The 72nd Annual Meeting of the Japanese Cancer Association 201310
菅沼雅美

抗がん剤のsynergistとして作用する緑茶カテキンを用いた新しいがん治療法
第12回新規素材研究会 201306
菅沼雅美

緑茶によるがん予防とがん治療・埼玉から発信する最近の話題
第30回農薬環境科学研究会 2012
菅沼雅美

Significancer of TNF-α inducing protein and its receptor nucleolin in Helicobacter pylori induced gastric cancer
Gyeongnam Regional Cancer Center International Symposium, (Jinju, Korea) 2012
Suganuma M.

New strategy of cancer treatment using a combination of green tea catchins and anti-cancer drugs
7th Asia Pacific Conference on Clinical Nutrition, (Bangkok, Thailand) 2011
Suganuma, M.

Cancer chemoprevention with green tea in humans: from its beginning to clinical applications
International Symposium of Oral Cancer and Cancer Prevention, (Seoul, Korea) 2008
Suganuma, M.

Human cancer prevention with green tea catechin act as chemical chaperone
2nd International Conference on Natural Products for Health and Beauty, (Ching Mai, Thailand) 2008
Suganuma, M.

Up-regulation of GADD153 gene with combination of green tea polyphenol and cancer preventive agent is a new mechanism of cancer prevention
3rd International Conference on Polyphenols and Health, (Kyoto, Japan) 2007
Suganuma, M.

Polyphenoles and antioxidant properties of green tea
Antioxidant Meeting, Roles of Antioxidants in Health and Diseases, (Khon Kaen, Thailand) 2005
Suganuma, M.

Gastric cancer prevention based on new molecular target of Helicobacter pylori: Tumor necrosis factor-α inducing protein (Tipα)
The 3nd Takeo Wada Cancer Research Symposium, (Khon Kaen, Thailand) 2005
Suganuma, M.

Green tea revisited: Maintaining health with emphasis on prevention
The First International Conference Natural Products for Health and Beauty, (Mahasarakham, Thailand) 2005
Suganuma, M.

TNF-α inducing protein (Tipα) is a new H. pylori carcinogenic factor
The Ajou International Symposium for Medical Science in Celebration of the 30th Anniversary of Ajou University (Suwon, Korea) 2003
Suganuma, M.

Lung cancer chemoprevention with green tea and monitoring by a new biomarker, hnRNP B1
3rd US-Japan Cooperative Cancer Research Program Symposium (Washington, U.S.A.) 2002
Suganuma, M.

Lung cancer chemoprevention in Japan
IASLC Third International Conference on Prevention and Early Detection of Lung Cancer 2001
Suganuma, M.

EGCGと抗がん剤の併用による、ヒトがん細胞株に対する抗がん効果の増強
The 74h Annual Meeting of the Japanese Cancer Association,The 74h Annual Meeting of the Japanese Cancer Association
Fujiki, H., Sueoka, E., Watanabe, T., Suganuma, M.