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西山 佳孝 ニシヤマ ヨシタカ

所属部署名 理工学研究科 生命科学部門 電話番号
職名 教授 ■FAX番号 048-858-3384
住所 埼玉県さいたま市桜区下大久保255 ■メールアドレス nishiyama@mail.saitama-u.ac.jp
■ホームページURL http://park.saitama-u.ac.jp/~kankyo/index.html

プロフィール

兼担研究科・学部

理学部 分子生物学科

研究分野

植物分子生理学

現在の研究課題

光合成の環境応答に関する分子生物学的研究
キーワード:光合成 , 環境応答 , タンパク質合成 , レドックス生化学

所属学会

所属学会
日本化学会
日本光合成学会
日本植物生理学会
所属学会役員担当
2015 - 2016 , 日本光合成学会 , 編集長
2013 - 2016 , 日本光合成学会 , 常任幹事・編集委員
2009 - 2012 , 日本植物生理学会 , 編集委員

学歴

出身大学院・研究科等
1994 , 東京大学 , 博士 , 工学系研究科 , 化学生命工学専攻 , 修了
1991 , 東京大学 , 修士 , 工学系研究科 , 工業化学専攻 , 修了
出身学校・専攻等(大学院を除く)
1988 , 東京大学 , 工学部 , 工業化学科 , 卒業
取得学位
博士(工学) , 東京大学

研究職歴等

研究職歴
2013 , 埼玉大学大学院理工学研究科・教授
2008 - 2013 , 埼玉大学大学院理工学研究科・准教授
2007 - 2008 , 愛媛大学無細胞生命科学工学研究センター・准教授
2003 - 2007 , 愛媛大学無細胞生命科学工学研究センター・助教授
2001 - 2003 , 愛媛大学理学部物質理学科(化学系)・助教授
1995 - 2001 , 岡崎国立共同研究機構基礎生物学研究所・助手
1994 - 1995 , 日本学術振興会特別研究員
研究職歴以外の職歴
2009 - 2010 , 名古屋大学大学院生命農学研究科・非常勤講師
2008 - 2009 , 愛媛大学大学院理工学研究科・非常勤講師
2000 - 2001 , フランス国立科学研究センター(CNRS)客員研究員
1997 - 1997 , オーストラリア国立大学・文部省在外研究員

研究活動業績

研究業績(著書・発表論文等)

論文
Light-inducible expression of translation factor EF-Tu during acclimation to strong light enhances the repair of photosystem II
,Proceedings of the National Academy of Sciences of the United States of America,116(42):21268-21273 201909
Jimbo, H., Izuhara, T., Hihara, Y., Hisabori, T. and Nishiyama, Y.

赤潮藻類の光応答
,光合成研究,85(2):147-155 201908
紫加田知幸、湯浅光貴、西山佳孝

RNA-seq analysis reveals genes related to photoreception, nutrient uptake, and toxicity in a noxious red-tide raphidophyte Chattonella antiqua
,Frontiers in Microbiology,10:1764 201907
Shikata, T., Takahashi, F., Nishide, H., Shigenobu, S., Kamei, Y., Sakamoto, S., Yamaguchi, M., Yuasa, K., Nishiyama, Y., Yamasaki, Y. and Uchiyama, I.

Overexpression of orange carotenoid protein protects the repair of photosystem II under strong light in Synechocystis sp. PCC 6803
,Plant and Cell Physiology,60(2):365-375 201901
Takahashi, H., Kusama, Y., Li, X., Takaichi, S. and Nishiyama, Y.

ATP is a driving force in the repair of photosystem II during photoinhibition
,Plant, Cell and Environment,41:285-299 2018
Murata, N. and Nishiyama, Y.

Oxidation of translation factor EF-Tu inhibits the repair of photosystem II
,Plant Physiology,176(4):2691-2699 2018
Jimbo, H., Yutthanasirikul, R., Nagano, T., Hisabori, T., Hihara, Y. and Nishiyama, Y.

Adverse effects of strong light and nitrogen deficiency cell viability, photosynthesis, and motility of the red-tide dinoflagellate Karenia mikimotoi
,Phycologia,57(5):525-533 2018
Yuasa, K., Shikata, T., Kuwahara, Y. and Nishiyama, Y.

Interaction of the GntR-family transcription factor Sll1961 with thioredoxin in the cyanobacterium Synechocystis sp. PCC 6803
,Scientific Reports,8:6666 2018
Kujirai, J., Nanba, S., Kadowaki, T., Oka, Y., Nishiyama, Y., Hayashi, Y., Arai, M. and Hihara, Y.

光合成におけるカロテノイドの機能
,植物科学の最前線(BSJ-Review),9:50-62 2018
髙橋拓子、西山佳孝

The LexA transcription factor regulates fatty acid biosynthetic genes in the cyanobacterium Synechocystis sp. PCC 6803
,The Plant Journal,92(2):189-198 2017
Kizawa, A., Kawahara, A., Takashima, K., Takimura, Y., Nishiyama, Y. and Hihara, Y.

Disturbance of cell-size determination by forced overproduction of sulfoquinovosyl diacylglycerol in the cyanobacterium Synechococcus elongatus PCC 7942
,Biochemical and Biophysical Research Communications,487(3):734-739 2017
Sato, N., Ebiya, Y., Kobayashi, R., Nishiyama, Y. and Tsuzuki, M.

Overexpressed superoxide dismutase and catalase act synergistically to protect the repair of PSII during photoinhibition in Synechococcus elongatus PCC 7942
,Plant and Cell Physiology,57(9):1899-1907 2016
Sae-Tang, P., Hihara, Y., Yumoto, I., Orikasa, Y., Okuyama, H. and Nishiyama, Y.

Rapid acquisition of high-affinity DNA aptamer motifs recognizing microbial cell surfaces using polymer-enhanced capillary transient isotachophoresis
,Chemical Communication,52(3):461-464 2016
Saito, S., Hirose, K., Tsuchida, M., Wakui, K., Yoshimoto, K., Nishiyama, Y. and Shibukawa, M.

Oxidation of a cysteine residue in elongation factor EF-Tu reversibly inhibits translation in the cyanobacterium Synechocystis sp. PCC 6803
,The Journal of Biological Chemistry,291(11):5860-5870 2016
Yutthanasirikul, R., Nagano, T., Jimbo, H., Hihara, Y., Kanamori, T., Ueda, T., Haruyama, T., Konno, H., Yoshida, K., Hisabori, T. and Nishiyama, Y.

A feed-forward loop consisting of the response regulator RpaB and the small RNA PsrR1 controls light acclimation of photosystem I gene expression in the cyanobacterium Synechocystis sp. PCC 6803
,Plant and Cell Physiology,57(4):813-823 2016
Kadowaki, T., Nagayama, R., Georg, J., Nishiyama, Y., Wilde, A., Hess, W. and Hihara, Y.

RNA-seq profiling reveals novel target genes of LexA in the cyanobacterium Synechocystis sp. PCC 6803
,Frontiers in Microbiology,7:193 2016
Kizawa, A., Kawahara, A., Takimura, Y., Nishiyama, Y. and Hihara, Y.

Light spectrum regulates cell accumulation during daytime in the raphidophyte Chattonella antiqua causing noxious red tides
,Journal of Photochemistry and Photobiology B Biology,160:128-133 2016
Shikata, T., Matsunaga, S., Kuwahara, Y., Iwahori, S. and Nishiyama, Y.

Moderate heat stress stimulates repair of photosystem II during photoinhibition in Synechocystis sp. PCC 6803
,Plant and Cell Physiology,57(11):2417-2426 2016
Ueno, M., Sae-Tang, P., Kusama, Y., Hihara, Y., Matsuda, M., Hasunuma, T. and Nishiyama, Y.

Identification of OmpR-family response regulators interacting with thioredoxin in the cyanobacterium Synechocystis sp. PCC 6803
,PLoS One,10(3):e0119107 2015
Kadowaki, T., Nishiyama, Y., Hisabori, T. and Hihara, Y.

Zeaxanthin and echinenone protect the repair of photosystem II from inhibition by singlet oxygen in Synechocystis sp. PCC 6803
,Plant and Cell Physiology,56(5):906-916 2015
Kusama, Y., Inoue, S., Jimbo, H., Takaichi, S., Sonoike, K., Hihara, Y. and Nishiyama, Y.

Oxidation of translation factor EF-G transiently retards the translational elongation cycle in Escherichia coli
,Journal of Biochemistry,158(2):165-172 2015
Nagano, T., Yutthanasirikul, R., Hihara, Y., Hisabori, T., Kanamori, T., Takeuchi, N., Ueda, T. and Nishiyama, Y.

Analysis of spontaneous suppressor mutants from the photomixotrophically-grown pmgA-disrupted mutant in the cyanobacterium Synechocystis sp. PCC 6803
,Photosynthesis Research,126(2-3):465-475 2015
Nishijima, Y., Kanesaki, Y., Yoshikawa, H., Ogawa, T., Sonoike, K., Nishiyama, Y. and Hihara, Y.

Revised scheme for the mechanism of photoinhibition and its application to enhance the abiotic stress tolerance of the photosynthetic machinery
,Applied Microbiology and Biotechnology,98(21):8777-8796 2014
Nishiyama, Y. and Murata, N.

The effects of dark incubation on cellular metabolism of the wild type and the mutant lacking the transcriptional regulator cyAbrB2 in the cyanobacterium Synechocystis sp. PCC 6803
,Life,4(4):770-787 2014
Hanai, M., Sato, Y., Miyagi, A., Kawai-Yamada, M., Tanaka, K., Kaneko, Y., Nishiyama, Y. and Hihara, Y.

Expression of a highly active catalase VktA in the cyanobacterium Synechococcus elongatus PCC 7942 alleviates the photoinhibition of photosystem II
,Photosynthesis Research,117:509-515 2013
Jimbo, H., Noda, A., Hayashi, H., Nagano, T., Yumoto, I., Orikasa, Y., Okuyama, H. and Nishiyama, Y.

Characterization of the plastidic phosphate translocators in the inducible crassulacean acid metabolism plant Mesembryanthemum crystallinum
,Bioscience Biotechnology and Biochemistry,77(7):1511-1516 2013
Kore-eda, S., Nozawa, A., Okada, Y., Takashi, K., Azad, M.A.K., Ohnishi, J., Nishiyama, Y. and Tozawa, Y.

Expression of a highly active catalase VktA in the cyanobacterium Synechococcus elongatus PCC 7942 alleviates the photoinhibition of photosystem II
,Photosynthesis Research,117:509-515 2013
Jimbo, H., Noda, A., Hayashi, H., Nagano, T., Yumoto, I., Orikasa, Y., Okuyama, H. and Nishiyama, Y.

Deletion of the transcriptional regulator cyAbrB2 de-regulates primary carbon metabolism in Synechocystis sp. PCC 6803
,Plant Physiology,162(2):1153-1163 2013
Kaniya, Y., Kizawa, A., Miyagi, A., Kawai-Yamada, M., Uchimiya, H., Kaneko, Y., Nishiyama, Y. and Hihara, Y.

Characterization of the plastidic phosphate translocators in the inducible crassulacean acid metabolism plant Mesembryanthemum crystallinum
,Bioscience, Biotechnology, and Biochemistry,77:1511-1516 2013
Kore-eda, S., Nozawa, A., Okada, Y., Takashi, K., Azad, M.A.K., Ohnishi, J., Nishiyama, Y. and Tozawa, Y.

Deletion of the transcriptional regulator cyAbrB2 de-regulates primary carbon metabolism in Synechocystis sp. PCC 6803
,Plant Physiology,162:1153-1163 2013
Kaniya, Y., Kizawa, A., Miyagi, A., Kawai-Yamada, M., Uchimiya, H., Kaneko, Y., Nishiyama, Y. and Hihara, Y.

光化学系IIの光阻害:光損傷と修復阻害のメカニズム
,光合成研究,23:50-56 2013
西山佳孝

A change in the sensitivity of elongation factor G to oxidation protects photosystem II from photoinhibition in Synechocystis sp. PCC 6803
,FEBS Letters,586(6):778-783 2012
Ejima, K., Kawaharada, T., Inoue, S., Kojima, K. and Nishiyama, Y.

The mechanism of photoinhibition in vivo: re-evaluation of the roles of catalase, α-tocopherol, non-photochemical quenching, and electron transport
,Biochimica et Biophysica Acta (BBA) - Bioenergetics,1817(8):1127-1133 2012
Murata, N., Allakhverdiev, S.I. and Nishiyama, Y.

Comparative study of the different mechanisms for zinc ion stress sensing in two cyanobacterial strains, Synechococcus sp. PCC 7942 and Synechocystis sp. PCC 6803
,Biophysics,8:103-109 2012
Morita, E.H., Kawamoto, S., Abe, S., Nishiyama, Y., Ikegami, T. and Hayashi, H.

Elongation Factor G Is a Critical Target during Oxidative Damage to the Translation System of Escherichia coli
,The Journal of Biological Chemistry,287(34):28697-28704 2012
Nagano, T., Kojima, K., Hisabori, T., Hayashi, H., Morita, E.H., Kanamori, T., Miyagi, T., Ueda, T. and Nishiyama, Y.

Protection by α-tocopherol of the repair of photosystem II during photoinhibition in Synechocystis sp. PCC 6803
,Biochimica et Biophysica Acta (BBA) - Bioenergetics,1807:236-241 2011
Inoue, S., Ejima, K., Iwai, E., Hayashi, H., Appel, J., Tyystjärvi, E., Murata, N. and Nishiyama, Y.

Protein synthesis is the primary target of reactive oxygen species in the photoinhibition of photosystem II
,Physiologia Plantarum,142:35-46 2011
Nishiyama, Y., Allakhverdiev, S.I. and Murata, N.

The PedR transcription factor interacts with thioredoxin to link photosynthesis with gene expression
,Biochemical Journal,431(1):135-140 2010
Horiuchi, M., Nakamura, K., Kojima, K., Nishiyama, Y., Hatakeyama, W., Hisabori, T. and Hihara, Y.

Synthesis of fatty acids de novo is required for photosynthetic acclimation of Synechocystis sp. PCC 6803 to high temperature
,Biochimica et Biophysica Acta (BBA) - Bioenergetics,1797(8):1483-1490 2010
Nanjo, Y., Mizusawa, N., Wada, H., Slabas, A.R., Hayashi, H., Nishiyama, Y.

Differential proteomic analysis using iTRAQ reveals changes in thylakoids associated with Photosystem II acquired thermotolerance in Synechocystis sp. PCC 6803
,Proteomics,10(10):1917-1929 2010
Rowland, J.G., Simon, W.J., Nishiyama, Y., Slabas, A.R.

Physiological impact of thioredoxin- and glutaredoxin-mediated redox regulation in cyanobacteria
,Advances in Botanical Research,52:187-205 2009
Nishiyama, Y., Hisabori, T.

Regulation of translation by the redox state of elongation factor G in the cyanobacterium Synechocystis sp. PCC 6803
,The Journal of Biological Chemistry,284(28):18685-18691 2009
Kojima, K., Motohashi, K., Morota, T., Oshita, M., Hisabori, T., Hayashi, H., Nishiyama, Y.

Role of elongation factor G in the inhibition of the synthesis of the D1 protein of photosystem II under oxidative stress
,Photosynthesis. Energy from the Sun:1319-1322 2008
Kojima, K., Oshita, M., Hayashi, H., Nishiyama, Y.

The plastid sigma factor SIG1 maintains photosystem I activity via regulated expression of the psaA operon in rice chloroplasts
,Plant Journal,52(1):124-132 200710
Tozawa, Y., Teraishi, M., Sasaki, T., Sonoike, K., Nishiyama, Y., Itaya, M., Miyao, A. and Hirochika, H.

Glycinebetaine alleviates the inhibitory effect of moderate heat stress on the repair of photosystem II during photoinhibition
,Biochimica et Biophysica Acta (BBA) - Bioenergetics,1767(12):1363-1371 2007
Allakhverdiev, S.I., Los, D.A., Mohanty, P., Nishiyama, Y. and Murata, N.

Photoinhibition of photosystem II under environmental stress
,Biochimica et Biophysica Acta (BBA) - Bioenergetics,1767(6):414-421 2007
Murata, N., Takahashi, S., Nishiyama, Y. and Allakhverdiev, S.I.

Oxidation of elongation factor G inhibits the synthesis of the D1 protein of photosystem II
,Molecular Microbiology,65(4):936-947 2007
Kojima, K., Oshita, M., Nanjo, Y., Kasai, K., Tozawa, Y., Hayashi, H. and Nishiyama, Y.

Regulation by environmental conditions of the repair of photosystem II in cyanobacteria
Springer,Advances in Photosynthesis and Respiration:193-203 2006
Nishiyama, Y., Allakhverdiev, S.I. and Murata, N.

A new paradigm for the action of reactive oxygen species in the photoinhibition of photosystem II
,Biochimica et Biophysica Acta (BBA) - Bioenergetics,1757(7):742-749 2006
Nishiyama, Y., Allakhverdiev, S.I. and Murata, N.

Very strong UV-A light temporally separates the photoinhibition of photosystem II into light-induced inactivation and repair
,Biochimica et Biophysica Acta (BBA) - Bioenergetics,1757(2):123-129 2006
Zsiros, O., Allakhverdiev, S.I., Higashi, S, Watanabe, M., Nishiyama, Y. and Murata, N.

The rpoH gene encoding heat shock factor δ32 of psychrophilic bacterium Colwellia maris
,Extremophiles,10(2):149-158 2006
Yamauchi, S., Okuyama, H., Nishiyama, Y. and Hayashi, H.

Acclimation of photosystem II to high temperature in a suspension culture of soybean (Glycine max) cells requires proteins that are associated with the thylakoid membrane
,Photosynthesis Research,90(3):223-232 2006
Nishiyama, Y., Takechi, K., Nanjo, Y., Murata, N. and Hayashi, H.

Two-Step Mechanism of Photodamage to Photosystem II: Step 1 Occurs at the Oxygen-Evolving Complex and Step 2 Occurs at the Photochemical Reaction Center
,Biochemistry,44(23):8494-8499 2005
Ohnishi, N., Allakhverdiev, S.I., Takahashi, S., Higashi, S., Watanabe, M., Nishiyama, Y. and Murata, N.

Systematic characterization of the ADP-ribose pyrophosphatase family in the cyanobacterium Synechocystis sp. strain PCC 6803
,Journal of Bacteriology,187(14):4984-4991 2005
Okuda, K., Hayashi, H. and Nishiyama, Y.

Inhibition of the repair of photosystem II by oxidative stress in cyanobacteria
,Photosynthesis Research,84(1-3):1-7 2005
Nishiyama, Y., Allakhverdiev, S.I. and Murata, N.

Systematic analysis of the relation of electron transport and ATP synthesis to the photodamage and repair of photosystem II in Synechocystis
,Plant Physiology,137(1):263-273 2005
Allakhverdiev, S.I., Nishiyama, Y., Takahashi, S., Miyairi, S., Suzuki, I. and Murata, N.

Singlet oxygen inhibits the repair of photosystem II by suppressing the translation elongation of the D1 protein in Synechocystis sp. PCC 6803
,Biochemistry,43(35):11321-11330 2004
Nishiyama, Y., Allakhverdiev, S.I., Yamamoto, H., Hayashi, H. and Murata, N.

Identification and characterization of NuhA, a novel Nudix hydrolase specific for ADP-ribose in the cyanobacterium Synechococcus sp. PCC 7002
,Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics,1699(1-2):245-252 2004
Okuda, K., Nishiyama, Y., Morita, E.H., and Hayashi, H.

Gene structure and transcriptional regulation of dnaK and dnaJ genes from a psychrophilic bacterium, Colwellia maris
,Extremophiles,8(4):283-290 2004
Yamauchi, S., Okuyama, H., Nishiyama, Y. and Hayashi, H.

Dissecting a cyanobacterial proteolytic system: efficiency in inducing degradation of the D1 protein of photosystem II in cyanobacteria and plants
,Biochimica et Biophysica Acta-Bioenergetics,1607(2-3):131-140 200312
Kanervo, E., Spetea, C., Nishiyama, Y., Murata, N., Andersson, B. and Aro, E.-M.

Refolding from denatured inclusion bodies, purification to homogeneity and simplified assay of MGDG synthases from land plants
,Protein Expression and Purification,31(1):79-87 200309
Nishiyama, Y., Hardré-Linard, H., Miras, S., Miége, C., Block, M.A., Revah, F., Joyard, J. and Maréchal, E.

Glycinebetaine protects the D1/D2/Cytb559 complex of photosystem II against photo-induced and heat-induced inactivation
,Journal of Plant Physiology,160(1):41-49 200301
Allakhverdiev, S.I., Hayashi, H., Nishiyama, Y., Ivanov, A.G., Aliev, J.A., Klimov, V.V., Murata, N. and Carpentier, R.

Stabilization of the oxygen-evolving complex of photosystem II by bicarbonate and glycinebetaine in thylakoid and subthylakoid preparations
,Functional Plant Biology,30(7):797-803 2003
Klimov, V.V., Allakhverdiev, S.I., Nishiyama, Y., Khorobrikh, A.A. and Murata, N.

Studies on the protein-DNA complex formation between the cyanobacterial transcription factors, SmtB and its homologues, functioning as zinc-ion sensors and the recognition DNA sequences
,Nucleic Acids Symposium Series,3(1):203-204 2003
Morita, E.H., Wakamatsu, M., Kawamoto, S., Nishiyama, Y. and Hayashi, H.

Salt stress inhibits the repair of photodamaged photosystem II by suppressing the transcription and translation of psbA genes in Synechocystis
,Plant Physiology,130(3):1443-1453 200211
Allakhverdiev, S.I., Nishiyama, Y., Miyairi, S., Yamamoto, H., Inagaki, N., Kanesaki, Y. and Murata, N.

Protection of the oxygen-evolving machinery by the extrinsic proteins of photosystem II is essential for development of cellular thermotolerance in Synechocystis sp. PCC 6803
,Plant and Cell Physiology,43(8):932-938 200208
Kimura, A., Eaton-Rye, J.J., Morita, E.H., Nishiyama, Y. and Hayashi, H.

No coordinated transcriptional regulation of the sod-kat antioxidative system in Synechocystis sp. PCC 6803
,Journal of Plant Physiology,159(7):805-807 200207
Ushimaru, T., Nishiyama, Y., Hayashi, H. and Murata, N.

Bioenergetic responses of Synechocystis 6803 fatty acid desaurase mutants at low temperature
,J. Bioenerg. Biomembr.,33:135-141 2001
Dilley, R.A., Nishiyama, Y., Gombos, Z. and Murata, N.

Inhibition by oxidative stress of the repair of photodamage to photosystem II
CSIRO Publishing,Proceedings of the 12th International Congress on Photosynthesis:S9-P009 2001
Nishiyama, Y., Yamamoto, H., Inaba, M., Yokota, A. and Murata, N.

Oxidative stress inhibits the repair of photodamage to the photosynthetic machinery
,The EMBO Journal,20(20):5587-5594 2001
Nishiyama, Y., Yamamoto, H., Allakhverdiev, S.I., Inaba, M., Yokota, A. and Murata, N.

Membrane dynamics as seen by Fourier transform infrared spectroscopy in a cyanobacterium, Synechocystis. PCC 6803
,Biochimica Et Biophysica Acta-Biomembranes,1509(1-2):409-419 200012
Szalontai, B., Nishiyama, Y., Gombos, Z. and Murata, N.

Ionic and osmotic effects of NaCl-induced inactivation of photosystems I and II in Synechococcus sp.
,Plant Physiology,123(3):1047-1056 200007
Allakhverdiev, S.I., Sakamoto, A., Nishiyama, Y., Inaba, M. and Murata, N.

Inactivation of photosystems I and II in response to osmotic stress in Synechococcus. Contribution of water channels.
,Plant Physiology,122(4):1201-1208 200004
Allakhverdiev, S.I., Sakamoto, A., Nishiyama, Y. and Murata, N.

Acclimation of the photosynthetic machinery to high temperature in Chlamydomonas requires synthesis de novo of proteins encoded by the nuclear and chloroplast genomes
,Plant Physiology,124(1):441-449 2000
Tanaka, Y., Nishiyama, Y. and Murata, N.

PsbU, a protein associated with photosystem II, is required for the acquisition of cellular thermotolerance in Synechococcus species PCC 7002
,Plant Physiology,120(1):301-308 199905
Nishiyama, Y., Los, D.A. and Murata, N.

Genetic engineering of the unsaturation of fatty acids in membrane lipids alters the tolerance of Synechocystis to salt stress
,Proceedings of the National Academy of Sciences of the United States of America,96(10):5862-5867 199905
Allakhverdiev, S.I., Nishiyama, Y., Suzuki, I., Tasaka, Y. and Murata, N.

Molecular characterization of the PEND protein, a novel bZip protein present in the envelope membrane that is the site of nucleoid replication in developing plastids
,Plant Cell,10(5):859-872 199805
Sato, N., Ohshima, K., Watanabe, A., Ohta, N., Nishiyama, Y., Joyard, J. and Douce, R.

Role of PsbU, an extrinsic protein of photosystem II, in the acquisition of thermotolerance in Synechococcus sp. PCC 7002
Kluwer Academic Publishers,Photosynthesis: Mechanisms and Effects,4:2449-2452 1998
Nishiyama, Y., Los, D.A. and Murata, N.

Molecular mechanisms of the low-temperature tolerance of the photosynthetic machinery
Elsevier Science,Stress Responses of Photosynthetic Organisms: Molecular Mechanisms and Molecular Regulations:93-112 1998
ISBN:0444828842
Murata, N. and Nishiyama, Y.

Identification of a cold-regulated RNA-binding protein from the marine cyanobacterium Synechococcus sp. PCC7002
,Journal of Plant Research,110(1100):405-410 199712
Sato, N., Maruyama, K., Nishiyama, Y. and Murata, N.

Thermal protection of the oxygen-evolving machinery by PsbU, an extrinsic protein of photosystem II, in Synechococcus species PCC 7002
,Plant Physiology,115(4):1473-1480 199712
Nishiyama, Y., Los, D.A., Hayashi, H. and Murata, N.

The action in vivo of glycine betaine in enhancement of tolerance of Synechococcus sp. PCC 7942 to low temperature
,Journal of Bacteriology,179(2):339-344 199701
Deshnium, P., Gombos, Z., Nishiyama, Y. and Murata, N.

Targeted mutagenesis of acyl-lipid desaturases in Synechocystis: evidence for the important roles of polyunsaturated membrane lipids in growth, respiration and photosynthesis
,The EMBO Journal,15(23):6416-6425 1996
Tasaka, Y., Gombos, Z., Nishiyama, Y., Mohanty, P., Ohba, T., Ohki, K. and Murata, N.

Photosynthetic Oxygen Evolution Is Stabilized by Cytochrome C(550) against Heat Inactivation in Synechococcus Sp Pcc-7002
,Plant Physiology,105(4):1313-1319 199408
Nishiyama, Y., Hayashi, H., Watanabe, T. and Murata, N.

Purification and substrate specificity of chlorophyllase from Chlorella regularis
,Chemistry Letters,23(1):69-72 199401
Nishiyama, Y., Kitamura, M., Tamura, S. and Watanabe, T.

Genetically engineered modification of plant chilling sensitivity and characterization of cyanobacterial heat shock proteins
Springer-Verlag,Biochemical and Cellular Mechanisms of Stress Tolerance in Plants:543-555 1994
ISBN:0387582150
Hayashi, H., Nishida, I., Ishizaki-Nishizawa, O., Nishiyama, Y. and Murata, N.

Photosynthetic adaptation to high temperature associated with thylakoid membranes of Synechococcus PCC7002
,Plant and Cell Physiology,34(2):337-343 199303
Nishiyama, Y., Kovacs, E., Lee, C.B., Hayashi, H., Watanabe, T. and Murata, N.

The adaptation of photosynthesis to high temperature in Synechococcus PCC7002. In Research in Photosynthesis
Kluwer Academic Publishers,Research in Photosynthesis,4:137-140 1992
Nishiyama, Y., Kovács, E., Hayashi, H., Watanabe, T. and Murata, N.

The molecular basis for the acclimation of photosynthesis toward temperature.
Kluwer Academic Publishers,Research in Photosynthesis,4:113-119 1992
Murata, N., Wada, H., Nishida, I., Gombos, Z., Nishiyama, Y., Hayashi, H., Sakamoto, T., Ishizaki-Nishizawa, O. and Higashi, S.

Inhibition of subtilisin BPN' by reaction site P1 mutants of Streptomyces subtilisin inhibitor
,Journal of Biochemistry,109(3):377-382 199103
Kojima, S., Nishiyama, Y., Kumagai, I. and Miura, K.I.

学会発表
シアノバクテリアSynechocystis sp. PCC 6803の超強光順化におけるカロテノイドの役割
第60回日本植物生理学会年会、名古屋 201903
出原太一、中澤小夏、神保晴彦、高市真一、西山佳孝

シアノバクテリアSynechococcus elongatus PCC 7942における翻訳因子EF-Gの酸化傷害の分子機構
第60回日本植物生理学会年会、名古屋 201903
桑野一志、高木健輔、是枝晋、西山佳孝是枝晋、西山佳孝晴彦、高市真一、西山佳孝

有害赤潮藻類Chattonella antiquaの活性酸素産生と光合成の関係
平成31年度日本水産学会春季大会(東京) 201903
湯浅光貴、鈴木和仁、紫加田知幸、北辻さほ、山﨑康裕、西山佳孝

Redox regulation of translation and high-light response of photosynthesis
Institute Seminar, Institute of Tropical Plant Sciences, National Cheng Kung University, Tainan, Taiwan 201811
Yoshitaka Nishiyama

Redox regulation of translation and high-light response of photosynthesis
CEA-Grenoble Seminar 201810
Yoshitaka Nishiyama

Effects of strong light and high temperature on photosystem II in red tide-forming algae Karenia mikimotoi and Chattonella antiqua
The 18th International Conference on Harmful Algae 201810
Yoshitaka Nishiyama, Yusuke Kuwahara, Koki Yuasa, Tomoyuki Shikata

シロイヌナズナ葉緑体翻訳因子の酸化傷害と光化学系IIの光阻害
日本植物学会第82回大会 201809
新庄梓、西山佳孝

有害赤潮藻類Chattonella antiquaの活性酸素発生に及ぼす光と栄養欠乏の影響
日本プランクトン学会・日本ベントス学会合同大会 201809
湯浅光貴、西山佳孝、紫加田知幸、北辻さほ、山﨑康裕

Redox regulation of translation in photosynthetic organisms
第91回日本生化学会 201809
Yoshitaka Nishiyama

Role of translational regulation in the repair of photosystem II
Japan-Finland Seminar 2018 201809
Yoshitaka Nishiyama

Role of translational regulation in the repair of photosystem II in Synechocystis sp. PCC 6803
16th International Symposium on Photosynthetic Prokaryotes (ISPP2018) 201808
Yoshitaka Nishiyama

シアノバクテリアの強光応答におけるサイクリック電子伝達の役割
第9回日本光合成学会年会 201805
高木健輔、高橋拓子、西山佳孝

緑藻クラミドモナスのMAPキナーゼによる葉緑体遺伝子psbAの発現制御
第9回日本光合成学会年会 201805
神保晴彦、西山佳孝、Krishna K. Niyogi

有害赤潮渦鞭毛藻Karenia mikimotoiの生育と光合成に対する強光と貧栄養の影響
第9回日本光合成学会年会 201805
湯浅光貴、紫加田知幸、西山佳孝

Redox regulation of translation and stress response of photosynthesis
Tokyo Tech CLS International Forum 2018 201803
Nishiyama, Y.

Enhanced expression of translation factor EF-Tu accelerates the repair of photosystem II during acclimation to strong light in Synechocystis sp. PCC 6803
Tokyo Tech CLS International Forum 2018 201803
Jimbo, H., Izuhara, T. and Nishiyama, Y.

Characterization of PGRL1 in photoprotection of PSI in the green alga Chlamydomonas reinhardtii,
Tokyo Tech CLS International Forum 2018 201803
Takahashi, H. and Nishiyama, Y.

Redox regulation of translation and high-light response of photosynthesis
Department Seminar, 2018.3.20, University of California, Berkeley 201803
Nishiyama, Y.

赤潮藻類Karenia mikimotoiの生残、光合成、遊泳に及ぼす貧栄養と強光の影響
平成30年度日本水産学会年会 201803
湯浅光貴、紫加田知幸、西山佳孝

Chlamydomonas reinhardtii の PSI 光防御における PGRL1 の役割
第59回日本植物生理学会年会 201803
髙橋拓子、西山佳孝

Synechocystis sp. PCC 6803の強光順化におけるPSII修復能力と翻訳因子EF-Tuの役割
第59回日本植物生理学会年会 201803
神保晴彦、出原太智、西山佳孝

シロイヌナズナの光化学系II光阻害における葉緑体翻訳因子 EF-Tu の役割
第59回日本植物生理学会年会 201803
新庄梓、神保晴彦、熊木裕香、西山佳孝

シアノバクテリアSynechocystis sp. PCC 6803 の超強光下における生存戦略
第59回日本植物生理学会年会 201803
出原太智、神保晴彦、高市真一、西山佳孝

翻訳因子のレドックス制御と光合成の強光応答
藍藻の分子生物学2017 201712
西山佳孝

シアノバクテリア光化学系IIの修復過程におけるオレンジカロテノイドプロテインの役割
藍藻の分子生物学2017 201712
高橋拓子、李新祥、山川伯壽、高市真一、伊藤繁、西山佳孝

Synechocystis sp. PCC 6803 における光化学系IIの強光順化機構
藍藻の分子生物学2017 201712
神保晴彦、出原太智、西山佳孝

光合成におけるカロテノイドの機能解析
日本植物学会第81回大会 201709
西山佳孝

緑藻クラミドモナスのPSI光防御におけるPGRL1の役割
第8回日本光合成学会年会 201705
高橋拓子、曽根和樹、西山佳孝

翻訳因子EF-Tuの酸化傷害と光化学系IIの修復阻害の関係
第8回日本光合成学会年会 201705
神保晴彦、Rayakorn Yutthanasirikul、西山佳孝

緑藻クラミドモナスの葉緑体光応答におけるMAPキナーゼの役割
第58回日本植物生理学会年会,日本植物生理学学会通信,129:67 201703
神保晴彦、西山佳孝、Krishna K. Niyogi

赤潮渦鞭毛藻Karenia mikimotoiの光合成に対する強光と貧栄養条件の影響
第58回日本植物生理学会年会,日本植物生理学学会通信,129:69 201703
湯浅光貴、紫加田知幸、西山佳孝

シアノバクテリア光化学系IIの光防御機構におけるオレンジカロテノイドプロテインの役割
第58回日本植物生理学会年会,日本植物生理学学会通信,129:71 201703
高橋拓子、草間友里、李新祥、高市真一、伊藤繁、山川伯壽、西山佳孝

シアノバクテリア光化学系IIの修復における熱ショックタンパク質DnaK3の役割
第58回日本植物生理学会年会,日本植物生理学学会通信,129:103 201703
河村大介、渡辺智、吉川博文、西山佳孝

シロイヌナズナ葉緑体翻訳因子EF-Tuの酸化傷害の分子機構
第58回日本植物生理学会年会,日本植物生理学学会通信,129:103 201703
熊木裕香、小林達巧、西山佳孝

光合成の環境応答におけるタンパク質合成系のレドックス制御の役割
ダイナミックアライアンスG3分科会 201612
西山佳孝

Effects of temperature stress on photoinhibition of photosystem II in Synechocystis sp. PCC 6803
Finnish-Japanese Symposium 2016,Abstract book for Finnish-Japanese Symposium 2016:21 201609
Nishiyama, Y.

Effects of temperature stress on photoinhibition of photosystem II in Synechocystis sp. PCC 6803
Finnish-Japanese Symposium 2016,Abstract book for Finnish-Japanese Symposium 2016:20 201609
Takahashi, H., Kusama, Y., Takaichi, S., Itoh, S., Yamakawa, H. and Nishiyama, Y.

Redox regulation of the repair of photosystem II under photoinhibition
The 17th International Congress on Photosynthesis Research,Program book for The 17th International Congress on Photosynthesis Research:10 201608
Nishiyama, Y.

微細藻類における強光阻害現象
日本プランクトン学会,日本プランクトン学会シンポジウム「光環境を巡る植物プランクトンの生理生態学最前線」要旨集:6 201603
西山佳孝

シロイヌナズナ葉緑体翻訳因子EF-GとEF-Tuの酸化ストレス応答
第57回日本植物生理学会年会,Abstract Book: Annual Meeting of JSPP 2016:290 201603
熊木裕香、濱川菜桜、米山拓、西山佳孝

赤潮藻類における光化学系IIの強光と高温ストレスに対する応答
第57回日本植物生理学会年会,Abstract Book: Annual Meeting of JSPP 2016:180 201603
桑原悠輔、紫加田知幸、西山佳孝

Synergistic effects of iron superoxide dismutase and catalase on the protection of photosynthesis to strong light in Synechococcus elongatus PCC 7942
第57回日本植物生理学会年会,Abstract Book: Annual Meeting of JSPP 2016:180 201603
Penporn Sae-Tang, Yoshitaka Nishiyama

Functional analysis of orange carotenoid protein in the protection of photosystem II against photoinhibition in Synechocystis sp. PCC 6803
第57回日本植物生理学会年会,Abstract Book: Annual Meeting of JSPP 2016:292 201603
高橋拓子、草間友里、李新祥、西山佳孝

光合成システムの強光応答
分子研 CIMoSセミナー 201603
西山佳孝

Regulation and protection of the repair of photosystem II under oxidative stress
Yamada Conference “International Symposium on Dynamics and Regulation of Photosynthesis”,Abstract of Yamada Conference “International Symposium on Dynamics and Regulation of Photosynthesis”:34-35 201510
Yoshitaka Nishiyama

Oxidative stress to translational machinery
Department Seminar, King’s Mongkut University of Technology, Thonburi, Thailand 201509
Yoshitaka Nishiyama

Fundamentals of photosynthesis
Department Seminar, King’s Mongkut University of Technology, Thonburi, Thailand 201509
Yoshitaka Nishiyama

Photo-oxidative stress to photosynthesis: a new mechanism for photoinhibition of PSII and roles of reactive oxygen species
Department Seminar at King’s Mongkut University of Technology, Thonburi, Thailand 201509
Yoshitaka Nishiyama

Redox regulation of protein synthesis in photosynthetic organisms
Tokyo Tech-HHH Dusseldorf Joint Symposium in Photosynthesis as a New Chemical Resource 201503
Nishiyama, Y.

光合成生物におけるタンパク質合成系のレドックス制御
物質・デバイス領域共同研究拠点特定研究課題(B-3)「生体機能物質の機能および制御の解析とバイオデバイスへの応用」第2回ワークショップ 201503
西山佳孝

タンパク質合成系の改変による光合成の強光ストレス耐性の向上
新学術“植物環境突破力”平成26年度領域会議 201503
西山佳孝

シアノバクテリア翻訳因子EF-Tuの酸化傷害機構とその生理学的意義
第56回日本植物生理学会年会 201503
神保晴彦、Rayakorn Yutthanasirikul、永野孝典、西山佳孝

シアノバクテリア光化学系IIの光防御機構における熱放散の役割
第56回日本植物生理学会年会 201503
草間友里、井上修平、神保晴彦、園池公毅、高市真一、西山佳孝

Role of reactive oxygen species in photoinhibition of photosystem II
The German-Japanese Binational Seminar 2015,The German-Japanese Binational Seminar 2015:27 201503
Nishiyama, Y.

Roles of carotenoids in the protection of photosystem II from photoinhibition
Japan-Finland Binational Seminar 2014 201410
Nishiyama, Y.

光化学系IIの光阻害に対する高温ストレスの影響
第78回日本植物学会年会 201409
西山佳孝、上野護、草間友里

リボソームのレドックス制御
第13回微生物研究会 201407
西山佳孝

シアノバクテリアの強光応答における翻訳因子EF-Gの役割
日本植物生理学会,第51回日本植物生理学会年会要旨集:335 201003
江島加余子、西山佳孝

強光条件下におけるシアノバクテリアの翻訳因子EF-Gのレドックス制御
日本植物生理学会,第51回日本植物生理学会年会要旨集:271 201003
諸田拓哉、小島幸治、日原由香子、本橋健、畠山和佳子、久堀徹、西山佳孝

Responses of photosystem II to high temperature and strong light in cyanobacteria
トゥルク大学生物学科セミナー 201003
西山佳孝

光化学系IIの高温適応における脂肪酸合成の役割
かずさDNA研究所研究会,「ラン藻の分子生物学2009」要旨集:23 200912
西山佳孝

光化学系IIの光阻害に対するα-トコフェロールの保護作用
かずさDNA研究所研究会,「ラン藻の分子生物学2009」要旨集:43 200912
井上修平、江島加余子、Jens Appel、村田紀夫、西山佳孝

光合成の強光応答における翻訳因子EF-Gの役割
かずさDNA研究所研究会,「ラン藻の分子生物学2009」要旨集:44 200912
江島加余子、西山佳孝

光合成と翻訳を結ぶレドックス制御機構
ラン藻ゲノム研究交流会 200907
西山佳孝

The redox regulation of elongation factor EF-Tu in photoinhibition of photosystem II in Synechocystis sp. PCC 6803.
Tokyo Tech-HHH Dusseldorf Joint Symposium in Photosynthesis as a New Chemical Resource
Jimbo, H., Yutthanasirikul, R., Nagano, T., Nishiyama, Y.

特許等知的財産

登録済特許
赤潮原因ラフィド藻の光逃避行動を誘導する方法

研究費

受託研究
2019-2019 , 赤潮被害防止対策技術の開発・魚毒性診断技術の開発 , 出資金による受託研究
2019-2019 , 赤潮被害防止対策技術の開発・八代海・鹿児島湾海域 , 出資金による受託研究
2017-2019 , ミルキング法によるバイオ燃料生産の高効率化と安定化 , 出資金による受託研究
科学研究費補助金(研究代表者)
2018-2020 , 光合成の強光耐性におけるタンパク質合成系の順化機構の役割 , 基盤研究(C)
2015-2017 , 光化学系II修復の強光順化メカニズムの解明 , 基盤研究(C)
2013-2014 , タンパク質合成系の改変による光合成の強光ストレス耐性の向上 , 新学術領域研究
2012-2014 , 光合成の強光ストレス傷害からの再生機構 , 基盤研究(C)
2009-2011 , 光合成における翻訳のレドックス制御と環境応答の分子機構 , 基盤研究(C)
2007-2008 , 翻訳のレドックス制御を介する光合成の環境応答の分子メカニズム , 基盤研究(C)
2005-2006 , 光合成の酸化ストレス傷害とその防御の分子機構 , 基盤研究(C)
2004-2004 , シアノバクテリアの高温適応を制御する遺伝子の網羅的解析 , 特定領域研究(2)
2003-2003 , シアノバクテリアの高温適応を制御する遺伝子群の同定 , 特定領域研究(2)
2002-2003 , 酸化ストレスによるタンパク質合成系の阻害機構 , 若手研究(B)
科学研究費補助金(研究分担者)
H8-H12 , 低温適応と低温耐性の分子機構 , 特別推進研究
H13-H13 , 低温センサーと低温適応の分子機構の研究 , 基盤研究(S)
その他
H22-H23 , 光合成の光ストレス傷害からの再生機構(旭硝子財団研究助成)

研究諸活動

在外研究員等
1997-1997 , 文部科学省在外研究員 , オーストラリア国立大学
研究者招聘
2004-2004 , 共同研究および講演

教育活動実績

授業等

2016 , 後期 , 基礎分子生物学 , 2016年から
2016 , 後期 , 一般分子生物学 , 2015年から
2016 , 後期 , 生物物理化学
2016 , 前期 , 植物分子生理学I , 2008年から
2016 , 前期 , 分子生物学基礎 , 2008年から
2016 , 後期 , 基礎生物学実験 , 2008年から
2016 , 前期 , 分子生物科学実験II , 2008年から
2016 , 通年 , 生命科学特別講義 , 2008年から
2016 , 後期 , 環境機能科学特論 , 2008年から
2016 , 前期 , 生物英語II , 2010年から
2016 , 通年 , 環境生物学演習
2016 , 通年 , 環境生物学輪講
2016 , 後期 , 細胞情報学特論2

研究員受入

2008-2009 , 翻訳因子のレドックス調節機構

管理運営実績

管理運営実績

学内兼務職
2016-2018 , 理工学研究科生命科学部門分子生物学コース長
2016-2017 , 理工学研究科生命科学部門長