キーワード検索

キーワード 詳細検索

プロフィール

津田　佐知子 ツダ サチコ

■所属部署名 理工学研究科生命科学部門 ■電話番号
■職名 准教授 ■FAX番号
■住所 埼玉県さいたま市桜区下大久保255 ■メールアドレス stsuda＠mail.saitama-u.ac.jp
■ホームページURL https://sites.google.com/view/tsudalab

プロフィール

兼担研究科・学部

理学部生体制御学科

研究分野

神経科学
発生生物学

所属学会

所属学会
日本発生生物学会
日本神経科学会
日本動物学会
北米神経科学会
日本分子生物学会

学歴

出身大学院・研究科等
2009 , 東京大学 , 博士 , 理学系研究科 , 生物科学専攻動物学課程
出身学校・専攻等(大学院を除く)
2004 , 東京大学 , 理学部 , 生物科学科動物学コース
取得学位
博士（理学） , 東京大学

受賞学術賞

2022 , 学長特別賞(みずき賞)
2018 , Narishige Zoological Science Award
2017 , Wellcome Trust Travel Awards (18th International Congress of Developmental Biology)
2012 , Grass Fellowship

研究職歴等

研究職歴
2019 , 埼玉大学大学院理工学研究科生命科学部門　准教授
2017 , 東京大学大学院理学系研究科 生物科学専攻　客員研究員
2014 , 埼玉大学研究機構 研究企画推進室　助教
2013 - 2013 , Lee Kong Chian School of Medicine, Neuroscience and Mental Health, Research Fellow (Prof. George Augustine）
2009 - 2013 , Duke-NUS Graduate Medical School, Neuroscience and Behavioral Disorders Program, Research Fellow（Prof. George Augustine）
2009 - 2009 , 東京大学大学院理学系研究科　特任研究員　（武田洋幸教授）
2007 - 2009 , 日本学術振興会特別研究員（DC2）
研究職歴以外の職歴
2012 - 2012 , 米国ウッズホール海洋生物学研究所　Visiting Researcher
2012 - 2012 , 米国ウッズホール海洋生物学研究所　Grass Fellow
2011 - 2011 , 米国ウッズホール海洋生物学研究所　Visiting Researcher
2010 - 2010 , 米国ウッズホール海洋生物学研究所　Visiting Researcher

研究活動業績

研究業績(著書・発表論文等)

著書
In vivo optical detection of membrane potentials in the cerebellum: voltage imaging of zebrafish
Springer (Measuring Cerebellar Function):229-244 2022
Hiyoshi K, Fukuda N, Shiraishi A, Tsuda S

Optogenetics. In: Gerlai, R.T. (Ed.), Behavioral and Neural Genetics of Zebrafish.
Elsevier, Academic Press:279–292 202004
ISBN:97801281752936
Sachiko Tsuda

Molecular Neuroendocrinology: From Genome to Physiology
Wiley-Blackwell:275–300
Ryuichi Nakajima, Sachiko Tsuda, Jinsook Kim, George Augustine

論文
Two-Photon Laser Ablation and In Vivo Wide-Field Imaging of Inferior Olive Neurons Revealed the Recovery of Olivocerebellar Circuits in Zebrafish
Int J Environ Res Public Health,18(16):8357 2021
Kanae Hiyoshi, Kaito Saito, Narumi Fukuda, Takahisa Matsuzaki, Hiroshi Yoshikawa and Sachiko Tsuda

In vivo wide-field voltage imaging in zebrafish with voltage sensitive dye and genetically encoded voltage indicator.
Development, Growth & Differentiation,63(8):417-428 2021
Kanae Hiyoshi, Asuka Shiraishi, Narumi Fukuda and Sachiko Tsuda

A globin-family protein, Cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish
Developmental Biology,472:1-17 2021
Takahashi K, Ito Y, Yoshimura M, Nikaido M, Yuikawa T, Kawamura A, Tsuda S, Kage D, Yamasu K.

Involvement of an Oct4-related PouV gene, pou5f3/pou2, in neurogenesis in the early neural plate of zebrafish embryos.
Developmental Biology,457(1):30 - 42 2020
Inomata C, Yuikawa T, Nakayama-Sadakiyo Y, Kobayashi K, Ikeda M, Chiba M, Konishi C, Ishioka A, Tsuda S, Yamasu K

4D imaging and characterization of dynamic migratory behaviors and fate of neuroprogenitors in zebrafish hindbrain.
Neuroscience Letters,690:112-119 2019
Sachiko Tsuda*, Kanae Hiyoshi, Hiroaki Miyazawa, Risa Kinno, Kyo Yamasu

Horizontal Boundary Cells, a Special Group of Somitic Cells
Cell Reports,27(3):928-939 2019
Kota Abe, Atsuko Shimada, Sayaka Tayama, Hotaka Nishikawa, Takuya Kaneko, Sachiko Tsuda, Akari Karaiwa, Takaaki Matsui, Tohru Ishitani, Hiroyuki Takeda

The role of gastrulation brain homeobox 2 (gbx2) in the development of the ventral telencephalon in zebrafish embryos
Differentiation,99:28-40 2018
Zhe Wang, Yukiko Nakayama, Sachiko Tsuda, Kyo Yamasu

Optical interrogation of neuronal circuitry in zebrafish using genetically encoded voltage indicators
Scientific Reports, 8(1):6048 2018
Hiroaki Miyazawa, Kanoko Okumura, Kanae Hiyoshi, Kazuhiro Maruyama, Hisaya Kakinuma, Ryunosuke Amo, Hitoshi Okamoto, Kyo Yamasu, Sachiko Tsuda

-Oxidation in ghrelin-producing cells is important for ghrelin acyl-modification
Scientific Reports,8:9176 2018
Chika Ikenoya, Shota Takemi, Arisa Kaminoda, Sayaka Aizawa, Shiomi Ojima, Zhi Gong, Rakhi Chacrabati, Daisuke Kondo, Reiko Wada, Toru Tanaka, Sachiko Tsuda, Takafumi Sakai, and Ichiro Sakata

Optical measurement of neuronal activity in the developing cerebellum of zebrafish using voltage sensitive dye imaging
NeuroReport,29:1349-1354 2018
Kanoko Okumura, Hisaya Kakinuma, Ryunosuke Amo, Hitoshi Okamoto, Kyo Yamasu, Sachiko Tsuda

Comprehensive analysis of target genes in zebrafish embryos reveals gbx2 involvement in neurogenesis.
Developmental Biology,S0012-1606(17):30282-8 2017
Yukiko Nakayama, TatsuyaYuikawa, SachikoTsuda, KyoYamasu

Study of termination of postprandial gastric contractions in humans, dogs, and Suncus murinus: role of motilin- and ghrelin- induced strong contraction.
Acta Physiologica,doi: 10.1111/apha.12933 2017
Takashi Mikami, Kazuma Ito, Hetzel Tartera Diaz, Per M. Hellström, Erito Mochiki, Shota Takemi, Toru Tanaka, Sachiko Tsuda, Takamichi Jogahara, Ichiro Sakata, Takafumi Sakai

Underlying mechanism of the cyclic migrating motor complex in Suncus murinus: a change in gastrointestinal pH is the key regulator
Physiological Reports,5 (1):e13105 2017
Anupom Mondal, Kouhei Koyama, Takashi Mikami, Taichi Horita, Shota Takemi, Sachiko Tsuda, Ichiro Sakata, Takafumi Sakai

Optogenetic mapping of local inhibitory circuitry in cerebellum reveals spatial coordination of interneurons via electrical synapses
Cell Reports,7(5):1601-13 2014
Kim, J., Lee, S., Tsuda, S., Zhang, X., Chow, N., Namburi, P., Kee, M., Cunha, C., Gloss, B., Feng, G., Augustine, G.J.

Next-generation transgenic mice for optogenetic analysis of neural circuits
Frontiers in Neural Circuits,7:1-24 2013
Asrican, B., Augustine, G.J., Berglund, K., Chen, S., Chow, N., Deisseroth, K., Feng, G., ..,Tsuda, S., Wen., Zhang., Zhao, S.　

Probing neural circuitry by combining optogenetic control of neural populations via micromirror arrays with voltage-sensitive dye imaging
Neuroscience Research (Optogenetics special issue),75(1):76-81 2013
Tsuda, S., Kee, M.Z., Cunha, C., Kim, J., Yang, P., Lowe, L.M., Augustine, G.J.　

High-speed optogenetic circuit mapping
Proceedings SPIE,　Optogenetics: Optical Methods for Cellular Control,8586:858603 2013
Augustine, G.J., Chen, S., Gill, H., Katarya, M., Kim, J., Kudolo, J., Lee, L., Lee, H., Lo, S., Nakajima, R., Park, M., Tan, G., Tang, Y., Teo, P., Tsuda, S., Wen, L., Yoon, S.　

Optogenetic mapping of brain circuitry
Proceeding SPIE, Nanosystems in Engineering and Medicine,8548:85483Y 2012
Augustine, G.J., Berglund, K., Gill, H., Hoffmann, C., Katarya, M., Kim, J., Kudolo, J., Lee, L., Lee, M., Lo, D., Nakajima, R., Park, M.Y., Tan, G., Tang, Y., Teo, P., Tsuda, S., Wen, L., Yoon, S.

Optogenetic probing of functional brain circuitry
Experimental Physiology,96(1):26-33 2011
Mancuso, J.J., Kim, J., Lee, S., Tsuda, S., Chow, N., Augustine, G.J.

FAK-mediated extracellular signals are essential for interkinetic nuclear migration and planar divisions in the neuroepithelium
Journal of Cell Science,123:484-496 2010
Tsuda, S., Kitagawa, T., Asakawa, S., Shimizu, N., Mitani, H., Shima, A., Tsutsumi, M., Hiroshi, H., Naruse, K., Ishikawa, Y., Takeda, H.

Phenotypic analysis of a novel chordin mutant in medaka
Developmental Dynamics,236:298-310 2007
Takashima, S., Shimada, A., Kobayashi, D., Yokoi, H., Narita, T., Jindo, T., Kage, T., Kitagawa, T., Kimura T.,.., Tsuda, S., Ooki, S., Kakihara, K., Hojo, M., Naruse, K., Mitani, H., Shima, A., Ishikawa, Y., Araki, K., Saga, Y., Takeda, H.

Right-elevated expression of charon is regulated by fluid flow in medaka Kupffer's vesicle
Developmental Growth Differentiation,49:395-405 2007
Hojo, M., Takashima, S., Kobayashi, D., Sumeragi, A., Shimada, A., Tsukahara, T., Yokoi, H., Narita, T.,.., Tsuda, S., Ooki, S., Kakihara, K., Naruse, K., Takeda, H.

学会発表
Purkinje cell populations form functional compartments in the cerebellum contributing to the sensorimotor integration in zebrafish larvae
第53回日本発生生物学会 210518
Kanae Hiyoshi, Eri Okuda, Narumi Fukuda, Kyo Yamasu, Sachiko Tsuda

In vivo application of genetically encoded voltage indicator ArcLight to the zebrafish brain
第45回日本神経科学大会 202307
Asuka Shiraishi, Narumi Fukuda, Mari Hishinuma, Kanae Hiyoshi, Kyo Yamasu, Sachiko Tsuda

光で探る脳の発生のしくみ
第３８回 国際生物学賞記念シンポジウム "魚の生物学：その生態、進化と発生" 202212
津田佐知子

光で捉える膜電位のダイナミクスと脳の発達
埼玉大学先端産業国際ラボラトリー メディカルイノベーション研究ユニット 第22回ワークショップ バイオイメージングの最前線－生体分子の可視化ー 202212
津田佐知子

Spatio-temporal analysis of zebrafish neural circuits by genetically encoded voltage indicator, ArcLight
第45回日本分子生物学会年会 202211
Asuka Shiraishi, Narumi Fukuda, Mari Hishinuma, Hiroaki Miyazawa, Kanae Hiyoshi, Sachiko Tsuda

How do neurons behave in populations and how are they formed during the development? -Spatiotemporal analysis in the zebrafish cerebellum-
IBRO-APRC Advanced School of Neuroscience 2022: Bioimaging and Proteogenomics for Cell-Based and Animal Research 202211
Sachiko Tsuda

小型魚類の群れ行動における 小脳プルキンエ細胞の機能
第92回日本動物学会大会 202209
齋藤魁登, 佐藤大我, 津田佐知子

Adaptation and Development of the Cerebellum in view of Eye Movements
第28回 小型魚類研究会 202209
Tomoya Murayama, Kanae Hiyoshi, Kaito Saito, Ryunosuke Togawa, Norihiro Katayama, Sachiko Tsuda

Voltage imaging for the study of brain function and development in zebrafish
Merocyanine 540 and FlaSh Celebration 202208
Sachiko Tsuda

光で捉える脳のダイナミクスとその発達
産総研セミナー 202203
津田佐知子

Clustered behavior of Purkinje cell populations in sensorimotor integration in the zebrafish cerebellum
The 26th Japanese Medaka and Zebrafish Meeting 202111
Kanae Hiyoshi, Eri Okuda, Narumi Fukuda, Kaito Saito, Masahiko Hibi, Kyo Yamasu, Sachiko Tsuda

Optical interrogation of neural population dynamics in the zebrafish cerebellum
NIBB-Academia Sinica International Webinar of Aquatic Model Organisms for Basic Biology to Human Disease Models 202103
Sachiko Tsuda

Anatomical and functional analysis of Inferior Olive-Cerebellar circuits in zebrafish larvae
The 26th Japanese Medaka and Zebrafish Meeting 202011
Narumi Fukuda, Kanae Hiyoshi, Eri Okuda, Kyo Yamasu, Sachiko Tsuda

Clustered behavior of Purkinje cell populations in the zebrafish cerebellum and its change with sensorimotor integration
第43回日本神経科学学会大会 202007
Kanae Hiyoshi, Eri Okuda, Narumi Fukuda, Kanoko Okumura, Kyo Yamasu, Sachiko Tsuda

ニューロンの集団ダイナミクスから見る小脳
第53回日本発生生物学会 ミニシンポジウム「The Cerebellum: Evolution, Development and Neuronal Circuits 」 202005
Sachiko Tsuda

光でひもとく小脳神経回路とそのダイナミクス
,EMEセミナー 2020
津田佐知子

Identifying functional compartments in the developing cerebellum: Calcium and voltage imaging in zebrafish
第49回北米神経科学会大会 201910
K. Hiyoshi, N. Fukuda, K. Okumura, K. Yamasu, S. Tsuda

眼球運動におけるプルキンエ細胞の集団活動にみる小型魚類の小脳区画と発達 -魚を用いて小脳の構築メカニズムに迫る-
第13回Motor control研究会, シンポジウム「小脳が関与する制御機能の最前線 -基礎と臨床の融合を目指して-」 201908
津田佐知子

発達中の小脳における機能的区画の３次元的理解: ゼブラフィッシュを用いた時空間的解析
第42回日本神経科学大会 201907
Kanae Hiyoshi, Narumi Fukuda, Kanoko Okumura, Kyo Yamasu, Sachiko Tsuda

膜電位イメージングにより捉えるゼブラフィッシュ小脳の発達
第42回日本神経科学大会, シンポジウム「膜電位イメージング:新展開」 201907
津田佐知子

小型魚類ゼブラフィッシュに観る小脳神経回路とその発達
第5回小脳システム研究会セミナー 201906
津田佐知子

Spatiotemporal analysis of functional compartments in the developing cerebellum by calcium and voltage imaging
The 14th International Zebrafish Conference 201906
Sachiko Tsuda

Probing the functional compartmentalization of the cerebellum in larval zebrafish
LB Cohen Symposium 201905
Sachiko Tsuda

Unraveling 3D structure of functional compartments in the developing cerebellum: Spatiotemporal analysis in zebrafish
52nd Annual Meeting of the Japanese Society of Developmental Biologists 201905
Kanae Hiyoshi, Narumi Fukuda, Kyo Yamasu, Sachiko Tsuda

Toward understanding functional development of the cerebellar circuitry with GFP and voltage imaging
5th Nagoya International Symposium on Neural Circuits: A Decade after "Discovery and Development of GFP": Expansion and Expectation 201903
Sachiko Tsuda

Toward understanding functional development of the cerebellar circuitry with GFP and voltage imaging
,5th Nagoya International Symposium on Neural Circuits: A Decade after "Discovery and Development of GFP": Expansion and Expectation 201903
Sachiko Tsuda

小型魚類を用いた小脳機能モジュール形成の時空間的解析
,第248回生理学東京談話会 201812
津田佐知子

Optical interrogation of neuronal circuitry in zebrafish using genetically encoded voltage indicators
,Voltage Imaging Symposium 201810
Sachiko Tsuda

Proving the functional development of the cerebellum: voltage imaging in the zebrafish brain
早稲田大学理工学術院,生命医科学専攻セミナー 201810
Sachiko Tsuda

Voltage imaging of the developing brain using VSD and genetically-encoded voltage indicators in zebrafish
,Merocyanine 540 Symposium 201809
Sachiko Tsuda

Optical measurement of neuronal activity in zebrafish using genetically encoded voltage indicators
,第24回小型魚類研究会 201808
Sachiko Tsuda

日吉 加菜映, 弥益 恭, 津田 佐知子, 小脳神経回路における機能的区画の形成：ゼブラフィッシュを用いた３次元的解析
,第41回日本神経科学大会 201807
日吉 加菜映, 弥益 恭, 津田 佐知子

Optical measurement of neuronal activity in zebrafish brain by genetically encoded voltage indicators
,第70回日本細胞生物学会第51回日本発生生物学会 合同大会 201806
Okumura K, Miyazawa H, Hiyoshi K, Maruyama K, Kakinuma H, Amo R, Okamoto H, Yamasu K, Tsuda S

膜電位イメージングを用いた、ゼブラフィッシュ小脳における神経活動の可視化
第70回日本動物学会関東支部大会:18 201803
奥村華乃子、宮澤碩彬、丸山和紘、弥益恭、津田佐知子

Optical interrogation of functional development of the cerebellar circuitry in zebrafish (ゼブラフィッシュ小脳神経回路の機能的発生 –膜電位イメージングによる試み-）
日本動物学会第88回大会 201709
Miyazawa H., Maruyama K., Okumura K., Hiyoshi K., Yamasu K. and Tsuda S.

光を用いた小脳神経回路の機能的発生
計測自動制御学会ライフエンジニアリング部門シンポジウム2017 201709
津田佐知子

3D analysis of functional development of cerebellar circuitry in zebrafish
The 23rd Japanese Medaka and Zebrafish Meeting 201708
Kanae Hiyoshi, Hiroaki Miyazawa, Kazuhiro Maruyama, Kyo Yamasu, Sachiko Tsuda

Optical interrogation of cerebellar circuitry via voltage sensor imaging in zebrafish（膜電位センサーを用いた、ゼブラフィッシュ小脳神経回路の活動イメージング）
第40回日本神経科学大会 (40th Annual Meeting of the Japan Neuroscience Society) (Oral) 201707
H. Miyazawa, K. Maruyama, K. Yamasu, S. Tsuda

Structural and functional compartmentalization in cerebellar development: 4D imaging in zebrafish
18th International Congress of Developmental Biology (第18回国際発生生物学会大会),Developmental Biology(145):S129 201706
S Tsuda

Cellular and molecular mechanisms for the establishment of the lifelong dorsoventral compartment boundary in the teleost trunk
18th International Congress of Developmental Biology (第18回国際発生生物学会大会）,Developmental Biology,145:S74 201706
Kota Abe, Sayaka Tayama, Sachiko Tsuda, Atsuko Shimada, Hiroyuki Takeda

3D analysis of functional development of cerebellar circuitry in zebrafish (ゼブラフィッシュを用いた小脳の機能的神経回路形成の３次元的解析)
第50回日本発生生物学会（50th Annual meeting of Japanese Society of Developmental Biologists） 201705
K Hiyoshi, H Miyazawa, K Maruyama, K Yamasu, S Tsuda

脊椎動物胚神経板での脳領域化および神経形成におけるgbx2の役割
第39回日本分子生物学会年会 201612
猪股千尋, 中山由紀子, 津田佐知子, 弥益恭

Functional organization of cerebellar circuitry and its development
第22回国際動物学会第87回日本動物学会大会合同大会 (22nd International Congress of Zoology) (Invited) 201611
Sachiko Tsuda

Dynamic migration of cell populations and functional compartmentalization in cerebellar development: 4D imaging in zebrafish
7th Asia Oceania Zebrafish Meeting (Oral) 201610
Sachiko Tsuda

Involvement of gbx2 in Neurogenesis in Vertebrate Embryos.
22nd Japanese Medaka Zebrafish Meeting 201608
Inomata C, Nakayama Y, Tsuda S and Yamasu K

Morphological and functional analysis of compartmentalization in cerebellar development
第22回小型魚類研究会 201608
Sachiko Tsuda, Kanae Hiyoshi, Kazuhiro Maruyama, Hiroaki Miyazawa, Risa Kinno, Kyo Yamasu

Structural and functional compartmentalization in cerebellar circuitry development: 4D imaging in zebrafish
第39回日本神経科学大会 (39th Annual Meeting of the Japan Neuroscience Society) (Oral) 201607
Sachiko Tsuda, Risa Kinno, Hiroaki Miyazawa, Kyo Yamasu

Development of the cholinergic neuron system and its regulation in the embryonic zebrafish brain.
第38回日本分子生物学会年会,プログラム:560 201512
Honoka Ohnuki, Minoru Takahashi, Sachiko Tsuda, Koichi Kawakami, Kyo Yamasu

Probing the developmental process of functional circuitry in the cerebellum: an all-optogenetic approach in zebrafish
第38回神経科学会大会 (38th Annual Meeting of the Japan Neuroscience Society) (Oral) 201507
Tsuda Sachiko, Yamasu Kyo

Dynamic migratory behaviors of gbx2-expressing cells during brain compartmentalization -4D imaging in zebrafish embryos-
第48回日本発生生物学会大会（48th Annual Meeting of Japanese Society of Developmental Biologists）（Oral） 201506
Sachiko Tsuda

All optical circuit mapping : combining optogenetics and voltage sensitive dye imaging
Optical measurements of membrane potential symposium (Invited) 201308
Sachiko Tsuda

Optogenetic mapping of local inhibitory circuitry in cerebellum reveals spatial coordination of interneurons via electrical synapses
Gordon Research Conference Cerebellum (Oral) 201108
Tsuda, S., Kim, J., Lee, S., Zhang, X., Chow, N., Namburi, P., Kee, M., Cunha, C., Gloss, B., Feng, G., Augustine, G.

Laminin regulates the interkinetic nuclear migration in the neuroepithelial cells
International Society of Developmental Biology Meeting (Oral) 200805
Sachiko Tsuda, Hiroyuki Takeda

Quantitative analysis of the dynamics of Purkinje cell populations in the whole cerebellum and the establishment of a behavior test for cerebellar learning in zebrafish larvae
第43回日本神経科学学会大会 200730
Eri Okuda, Kanae Hiyoshi, Kyo Yamasu, Sachiko Tsuda