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TAKAHASHI Tomoko

Faculty: Graduate School of Science and Engineering TEL:
Position: Assistant Professor ■FAX:
Address: 255 Shimo-Okubo, Sakura-ku, Saitama City, Saitama 338-8570, JAPAN ■Mail Address:
■Web site: https://researchmap.jp/tomokotakahas

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Faculty of Science

Research

Books, Articles, etc.

Articles
AraC-induced neuron-like differentiation of human NTERA2/D1cells and quantification of endogenous pre-mir-106b and 19b levels.
,microPubl Biol. 2023
Kaneko Y, Takahashi T.

Establishing an efficient protoplast transient expression system for investigation of floral thermogenesis in aroids
,Plant Cell Rep.,41(1):263-275 2022
Maekawa H, Otsubo M, Sato MP, Takahashi T, Mizoguchi K, Koyamatsu D, Inaba T, *Ito-Inaba Y

Mammalian antiviral systems directed by small RNA
,PLoS Pathog. ,17:e1010091 2021
*Takahashi T, Heaton SM, *Parrish NF

TRBP-Dicer interaction enhances HIV-1 TAR RNA translation via TAR microRNA processing, repressing host-cell apoptosis.
,Biol. Open,9(2):bio050435 2020
Komori C, Takahashi T, Nakano Y, *Ui-Tei K.

Mutual regulation of RNA silencing and the IFN response as an antiviral defense system in mammalian cells.
,Int. J. Mol. Sci.,21:E1348 2020
*Takahashi T, *Ui-Tei K.

LGP2 virus sensor enhances apoptosis by upregulating apoptosis regulatory genes through TRBP-bound miRNAs during viral infection.
,Nucleic Acids Res.,48(3):1494-1507 2019
Takahashi T, Nakano Y, Onomoto K, Yoneyama M, *Ui-Tei K.

Current Status for Application of RNA Interference Technology as Nucleic Acid Drug.
,InTechOpen “Gene Expression and Regulation in Mammalian Cells”:149-162 2018
Takahashi T, Nakano Y, *Ui-Tei K.

Takahashi T, Nakano Y, Onomoto K, Murakami F, Komori C, Suzuki Y, Yoneyama M, *Ui-Tei K.
,Nucleic Acids Res.,46(17):9134-9147 2018
LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs.

Virus sensor RIG-I represses RNA interference by interacting with TRBP through LGP2 in mammalian cells.
,Genes,9:511 2018
Takahashi T, Nakano Y, Onomoto K, Yoneyama M, *Ui-Tei K.

Chemical modification of the siRNA seed region suppresses off-target effects by steric hindrance to base-pairing with targets.
,ACS Omega,2:2055-2064 2017
Iribe H, Miyamoto K, Takahashi T, Kobayashi Y, Leo J, Aida M, *Ui-Tei K.

Control of the localization and function of a miRNA silencing component TNRC6A by Argonaute protein.
,Nucleic Acids Res.,43(20):9856-9873 2015
Nishi K, Takahashi T, Suzawa M, Miyakawa T, Nagasawa T, Ming Y, Tanokura M, *Ui-Tei K

The siRNA Non-Seed Region and its Target Sequences are Auxiliary Determinants of Off-Target Effects.
,PLoS Comput. Biol.,11(12):e1004656 2015
Kamola PJ, Nakano Y, Takahashi T, Wilson PA, *Ui-Tei K

Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells.
,Nucleic Acids Res.,42(8):5256-5269 2014
Takahashi T, Zenno S, Ishibashi O, Takizawa T, Saigo K, *Ui-Tei K

Distinguishable In Vitro Binding Mode of Monomeric TRBP and Dimeric PACT with siRNA
,PLoS ONE,8:e63434 2013
Takahashi T, Miyakawa T, Zenno S, Nishi K, Tanokura M, *Ui-Tei K

Thermodynamic control of small RNA-mediated gene silencing.
,Front. Genet.,3:101 2012
*Ui-Tei K, Nishi K, Takahashi T, Nagasawa T

The role of multiple HLR1 sequences in the regulation of the dual promoters of the psaAB genes in Synechocystis sp. PCC 6803.
,J. Bacteriol.,192(15):4031-4036 2010
Takahashi T, Nakai N, Muramatsu M, *Hihara Y

The response regulator RpaB binds to the upstream element of photosystem I genes to work for positive regulation under low-light conditions in Synechocystis sp. Strain PCC 6803.
,J. Bacteriol.,191(5):1581-1586 2009
Seino Y, Takahashi T, *Hihara Y

The regulation of persistent Borna disease virus infection by RNA silencing factors in human cells
,Biochemical and Biophysical Research Communications
Kaneko Y, Naito Y, Koide R, Parrish NF, *Takahashi T

CRISPRi knockdown of the cyabrB1 gene induces the divergently transcribed icfG and sll1783 operons related to carbon metabolism in the cyanobacterium Synechocystis sp. PCC 6803.
,J. Gen. Appl. Microbiol.
Hishida A, Shirai R, Higo A, Matsutani M, Nimura-Matsune K, Takahashi T, Watanabe S, Ehira S, Hihara Y.