Performance information

• Simultaneous visualization of membrane fluidity and morphology defines adhesion signatures of cancer cells.　　　　　　　　　　　　　　　
  Takahisa Matsuzaki; Mai Fujii; Hayata Noro; Shodai Togo; Mami Watanabe; Masami Suganuma; Shivani Sharma; Naritaka Kobayashi; Ryuzo Kawamura; Seiichiro Nakabayashi; Hiroshi Y Yoshikawa
  Proceedings of the National Academy of Sciences of the United States of America, Volume：121, Number：50, First page：e2412914121, Dec. 2024, [Reviewed], ［International magazine］
  We developed an advanced optical microscope for the simultaneous visualization of membrane fluidity and morphology to define cell adhesion signatures. This microscope combines ratiometric spectral imaging of membrane fluidity and interferometric imaging of membrane morphology. As a preliminary demonstration, we simultaneously visualized the interface between a giant unilamellar vesicle (GUV) and a glass substrate at different temperatures. We identified more fluid regions of the membrane and membrane adhesion sites (conversely, low-fluidic, ordered membrane domains correlate with nonadhered regions). This microscopic system was applied to human breast cancer cell lines with different malignancies; then, we identified adhesion signature of cancer cells: 1) low-fluidic, ordered membrane domains at the cell periphery and 2) large fluidic deviation at the nonadhered region. Inhibition of the cholesterol synthesis pathway suppresses the ordered membrane domains at the cancer cell periphery; thus, high level of cholesterol supports the appearance. Furthermore, an inhibitor of the unsaturated lipid synthesis pathway suppressed the large fluidic deviation at the nonadhered region; variation of unsaturated lipids contributes to heterogeneity of the cancer membrane. Therefore, our advanced optical microscopy enables us to couple membrane physical properties with cell adhesion, leading to definition of adhesion signatures of broad cell types, not just for cancer cells, that regulate life phenomena.
  English, Scientific journal
  DOI：https://doi.org/10.1073/pnas.2412914121
  DOI ID：10.1073/pnas.2412914121, PubMed ID：39636859
• In-Situ Observation of DL-Alanine Crystallization from a Laser-Trapped Dense Liquid Droplet as a Heterogeneous Nucleation Site
  Hiromasa Niinomi; Hiroshi Y Yoshikawa; Ryuzo Kawamura; Tomoya Yamazaki; Tomoya Oshikiri; Masaru Nakagawa
  Chemistry Letters, May 2024, [Reviewed]
  Abstract
  
  Nucleation from an aqueous solution is an important step in crystallization which controls the physicochemical properties of crystalline materials. Although dense liquid droplets are considered as a precursor of a crystal in the two-step nucleation model, their actual role is unclear. Our in-situ microscopic observations of the crystallization of DL-alanine from a dense liquid droplet trapped by laser tweezers show that the liquid droplets play the role of a substrate facilitating heterogeneous nucleation rather than a precursor of a crystal.
  Oxford University Press (OUP), Scientific journal
  DOI：https://doi.org/10.1093/chemle/upae100
  DOI ID：10.1093/chemle/upae100, ISSN：0366-7022, eISSN：1348-0715
• Label-free 3D tracking of biological micro-objects using RGB pinholes　　　　　　　　　　　　　　　
  Doyeop Kim; Takahisa Matsuzaki; Hiroshi Y. Yoshikawa; Ryuzo Kawamura
  Japanese Journal of Applied Physics (Special Issues), Apr. 2024, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.35848/1347-4065/ad3969
  DOI ID：10.35848/1347-4065/ad3969
• Mie-Resonant Nanophotonic-Enhancement of Asymmetry in Sodium Chlorate Chiral Crystallization.　　　　　　　　　　　　　　　
  Hiromasa Niinomi; Kazuhiro Gotoh; Naoki Takano; Miho Tagawa; Iori Morita; Akiko Onuma; Hiroshi Y Yoshikawa; Ryuzo Kawamura; Tomoya Oshikiri; Masaru Nakagawa
  The journal of physical chemistry letters, First page：1564, Last page：1571, Feb. 2024, [Reviewed], ［International magazine］
  Studies on chiral spectroscopy have recently demonstrated strong enhancement of chiral light-matter interaction in the chiral near-field of Mie resonance in high-refractive-index dielectric nanostructures by studies on chiral spectroscopy. This situation has motivated researchers to demonstrate effective chiral photosynthesis under a chiral near-field beyond circularly polarized light (CPL) as a chiral source. However, the effectivity of the chiral near-field of Mie resonance for chiral photosynthesis has not been clearly demonstrated. One major challenge is the experimental difficulty in evaluating enantiomeric excess of a trace amount of chiral products synthesized in the near-field. Here, by adopting sodium chlorate chiral crystallization as a phenomenon that includes both synthesis and the amplification of chiral products, we show that crystallization on a Mie-resonant silicon metasurface excited by CPL yields a statistically significant large crystal enantiomeric excess of ∼18%, which cannot be achieved merely by CPL. This result provides implications for efficient chiral photosynthesis in a chiral near-field.
  English, Scientific journal
  DOI：https://doi.org/10.1021/acs.jpclett.3c03303
  DOI ID：10.1021/acs.jpclett.3c03303, PubMed ID：38316420
• Advanced Interferometry with 3-D Structured Illumination Reveals the Surface Fine Structure of Complex Biospecimens.　　　　　　　　　　　　　　　
  Takahisa Matsuzaki; Ryuzo Kawamura; Akihisa Yamamoto; Hozumi Takahashi; Mai Fujii; Shodai Togo; Yosuke Yoneyama; Fumihiko Hakuno; Shin-Ichiro Takahashi; Masami Suganuma; Seiichiro Nakabayashi; Shivani Sharma; James K. Gimzewski; Hiroshi Y. Yoshikawa
  The Journal of Physical Chemistry Letters, Volume：jz-2023-027675 (acs.jpclett.3c02767), Jan. 2024, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/acs.jpclett.3c02767
  DOI ID：10.1021/acs.jpclett.3c02767
• Spatiotemporal Control of Polymorphic Phase Transition of Glycine Crystals by Three-Dimensional Femtosecond Laser Ablation Processing
  Hozumi Takahashi; Yudai Yoshimura; Ryota Murai; Ryuzo Kawamura; Mihoko Maruyama; Masashi Yoshimura; Yusuke Mori; Hiroshi Y. Yoshikawa
  The Journal of Physical Chemistry Letters, Volume：15, Number：1, First page：180, Last page：186, Dec. 2023, [Reviewed]
  American Chemical Society (ACS), Scientific journal
  DOI：https://doi.org/10.1021/acs.jpclett.3c02769
  DOI ID：10.1021/acs.jpclett.3c02769, ISSN：1948-7185, eISSN：1948-7185
• Preparation of mechanically patterned hydrogels for controlling the self-condensation of cells　　　　　　　　　　　　　　　
  Takahisa Matsuzaki; Yuma Kawano; Momoka Horikiri; Yuko Shimokawa; Takashi Yamazaki; Nao Okuma; Hiroyuki Koike; Masaki Kimura; Ryuzo Kawamura; Yosuke Yoneyama; Yasuro Furuichi; Fumihiko Hakuno; Shin-Ichiro Takahashi; Seiichiro Nakabayashi; Satoshi Okamoto; Hiromitsu Nakauchi; Hideki Taniguchi; Takanori Takebe; Hiroshi Y. Yoshikawa
  STAR Protocols, Volume：4, Number：3, First page：102471, Last page：102471, Sep. 2023, [Reviewed]
  Elsevier BV, Scientific journal
  DOI：https://doi.org/10.1016/j.xpro.2023.102471
  DOI ID：10.1016/j.xpro.2023.102471, ISSN：2666-1667
• Surface-limited reactions for spatial control of kinesin–microtubule motility assays using indirect irradiation of an electron beam
  Hiroki Miyazako; Ryuzo Kawamura; Takayuki Hoshino
  Biomicrofluidics, Volume：16, Number：6, First page：064105, Last page：064105, Dec. 2022, [Reviewed]
  Gliding of microtubules (MTs) on kinesins has been applied to lab-on-a-chip devices, which enable autonomous transportation and detection of biomolecules in the field of bioengineering. For rapid fabrication and evaluation of the kinesin–MT based devices, optical control techniques have been developed for control of kinesin activity and density; however, use of caged molecules lacks spatial controllability for long-term experiments, and direct irradiations of UV light onto kinesin-coated surfaces are inherently damaging to MTs due to their depth limit since the heights of the kinesin–MT systems are at the tens of a nanometer scale. Considering surface electric fields in electrolytic solutions are shielded at the nanometer scale due to Debye shielding, in this study, we show that fine spatial control of kinesin density and activity is enabled using surface-limited electrochemical reactions induced by indirect irradiations of an electron beam (EB). An EB is indirectly irradiated onto the kinesins through a 100-nm-thick silicon nitride membrane, and the electrons scattered in the membrane can cause localized electrochemical effects to the kinesins. We show that these localized electrochemical effects cause both ablation of kinesins and motility control of kinesin activity by changing the EB acceleration voltage. In particular, the latter is achieved without complete ablation of MTs, though the MTs are indirectly irradiated by the EB. As a demonstration of on-demand control of gliding MTs, we show the accumulation of the MTs on a target area by scanning the EB. The proposed accumulation technique will lead to rapid prototyping of microdevices based on MT–kinesin motility assay systems.
  AIP Publishing, Scientific journal
  DOI：https://doi.org/10.1063/5.0124921
  DOI ID：10.1063/5.0124921, eISSN：1932-1058
• Mechanical guidance of self-condensation patterns of differentiating progeny　　　　　　　　　　　　　　　
  Takahisa Matsuzaki; Yuko Shimokawa; Hiroyuki Koike; Masaki Kimura; Yuma Kawano; Nao Okuma; Ryuzo Kawamura; Yosuke Yoneyama; Yasuro Furuichi; Fumihiko Hakuno; Shin-Ichiro Takahashi; Seiichiro Nakabayashi; Satoshi Okamoto; Hiromitsu Nakauchi; Hideki Taniguchi; Takanori Takebe; Hiroshi Y. Yoshikawa
  iScience, First page：105109, Last page：105109, Sep. 2022, [Reviewed]
  Elsevier BV, Scientific journal
  DOI：https://doi.org/10.1016/j.isci.2022.105109
  DOI ID：10.1016/j.isci.2022.105109, ISSN：2589-0042
• Intelligent gels – artificial soft tissue for the next era
  Ken‐Ichi Sano; Ryuzo Kawamura; Yoshihito Osada
  Polymer International, Volume：71, Number：6, First page：616, Last page：629, Jun. 2022, [Reviewed]
  Wiley, Scientific journal
  DOI：https://doi.org/10.1002/pi.6305
  DOI ID：10.1002/pi.6305, ISSN：0959-8103, eISSN：1097-0126
• Chiral Optical Force Generated by a Superchiral Near-Field of a Plasmonic Triangle Trimer as Origin of Giant Bias in Chiral Nucleation: A Simulation Study　　　　　　　　　　　　　　　
  Hiromasa Niinomi; Teruki Sugiyama; An-Chieh Cheng; Miho Tagawa; Toru Ujihara; Hiroshi Y. Yoshikawa; Ryuzo Kawamura; Jun Nozawa; Junpei T. Okada; Satoshi Uda
  The Journal of Physical Chemistry C, Volume：125, Number：11, First page：6209, Last page：6221, Mar. 2021, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/acs.jpcc.0c11109
  DOI ID：10.1021/acs.jpcc.0c11109, ISSN：1932-7447, eISSN：1932-7455, Web of Science ID：WOS:000635441700026
• Stiffness distribution analysis in indentation depth direction reveals clear mechanical features of cells and organoids by using AFM　　　　　　　　　　　　　　　
  Naritaka Kobayashi; Shodai Togo; Takahisa Matsuzaki; Kaede Hashiseko; Ryuzo Kawamura; Masami Suganuma; Seiichiro Nakabayashi; Yosuke Yoneyama; Rie Ouchi; Takanori Takebe; Hiroshi Y Yoshikawa
  Applied Physics Express, Volume：13, Number：9, First page：097001, Last page：097001, Sep. 2020, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.35848/1882-0786/abaeb5
  DOI ID：10.35848/1882-0786/abaeb5, ISSN：1882-0778, eISSN：1882-0786, Web of Science ID：WOS:000565743700001
• Plasmonic Manipulation of Sodium Chlorate Chiral Crystallization: Directed Chirality Transfer via Contact-Induced Polymorphic Transformation and Formation of Liquid Precursor　　　　　　　　　　　　　　　
  Hiromasa Niinomi; Teruki Sugiyama; Miho Tagawa; Toru Ujihara; Takashige Omatsu; Katsuhiko Miyamoto; Hiroshi Y. Yoshikawa; Ryuzo Kawamura; Jun Nozawa; Junpei T. Okada; Satoshi Uda
  Crystal Growth & Design, Volume：20, Number：8, First page：5493, Last page：5507, Aug. 2020, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/acs.cgd.0c00693
  DOI ID：10.1021/acs.cgd.0c00693, ISSN：1528-7483, eISSN：1528-7505, Web of Science ID：WOS:000558791100067
• Selective electrical switching of molecular motors by dynamic virtual cathode　　　　　　　　　　　　　　　
  Kenta Hatazawa; Ryuzo Kawamura; Takayuki Hoshino
  MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, First page：360, Last page：361, Jul. 2020, [Reviewed]
  International conference proceedings
  Scopus：https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85098277116&origin=inward
  Scopus Citedby：https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85098277116&origin=inward
  SCOPUS ID：85098277116
• Simultaneous atomic-resolution flexural and torsional imaging in liquid by frequency modulation atomic force microscopy　　　　　　　　　　　　　　　
  Megumi Umemoto; Ryuzo Kawamura; Hiroshi Y. Yoshikawa; Seiichiro Nakabayashi; Naritaka Kobayashi
  JAPANESE JOURNAL OF APPLIED PHYSICS, Volume：59, Jun. 2020, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.35848/1347-4065/ab7479
  DOI ID：10.35848/1347-4065/ab7479, ISSN：0021-4922, eISSN：1347-4065, Web of Science ID：WOS:000519637800011
• Quantitative evaluation of the impact of artificial cell adhesion via DNA hybridization on E-cadherin-mediated cell adhesion.　　　　　　　　　　　　　　　
  Shodai Togo; Ken Sato; Ryuzo Kawamura; Naritaka Kobayashi; Makoto Noiri; Seiichiro Nakabayashi; Yuji Teramura; Hiroshi Y Yoshikawa
  APL bioengineering, Volume：4, Number：1, First page：016103, Last page：016103, Mar. 2020, [Reviewed], ［International magazine］
  Programmable cell adhesion with DNA hybridization is a promising approach for fabricating various tissue architectures without sophisticated instrumentation. However, little is known about how this artificial interaction influences the binding of cell adhesion proteins, E-cadherin. In this work, we designed a planar and fluid lipid membrane displaying E-cadherin and/or single-strand DNA with well-defined densities. Visualization of cells on membranes by fluorescence and interference microscopy revealed cell adhesion to be a two-step process: artificial adhesion by DNA hybridization within a few minutes followed by biological adhesion via cadherin-cadherin binding within hours. Furthermore, we discovered that DNA hybridization can substantially facilitate E-cadherin-mediated cell adhesion. The promotive effect is probably due to the enforced binding between E-cadherin molecules in geometrical confinement between two membranes. Our in vitro model of cell adhesion can potentially be used to design functional synthetic molecules that can regulate cell adhesion via cell adhesion proteins for tissue engineering.
  English
  DOI：https://doi.org/10.1063/1.5123749
  DOI ID：10.1063/1.5123749, PubMed ID：32002498, PubMed Central ID：PMC6984976
• Employing Cytoskeletal Treadmilling in Bio-actuators
  Ryuzo Kawamura; Ken-Ichi Sano; Yoshihito Osada
  Soft Actuators, First page：711, Last page：722, Aug. 2019
  Springer Singapore, In book
  DOI：https://doi.org/10.1007/978-981-13-6850-9_40
  DOI ID：10.1007/978-981-13-6850-9_40
• Pause of the target gliding microtuble on the virtual cathode　　　　　　　　　　　　　　　
  Kenta Hatazawa; Hiroki Miyazako; Ryuzo Kawamura; Takayuki Hoshino
  Biochemical and Biophysical Research Communications, Volume：514, Number：3, First page：821, Last page：825, Jun. 2019, [Reviewed]
  Elsevier BV, Scientific journal
  DOI：https://doi.org/10.1016/j.bbrc.2019.04.200
  DOI ID：10.1016/j.bbrc.2019.04.200, ISSN：0006-291X
• Start/Stop Motion Control of a Targeted Microtubule Using Virtual Cathode Display　　　　　　　　　　　　　　　
  Kenta Hatazawa; Hiroki Miyazako; Ryuzo Kawamura; Takayuki Hoshino
  Biochem. Biophys. Res. Comm, Volume：514, First page：821, Last page：825, May 2019, [Reviewed]
• Reversible surface functionalization of motor proteins for sustainable motility　　　　　　　　　　　　　　　
  Keisuke Meguriya; Shiori Kikuchi; Naritaka Kobayashi; Hiroshi Y. Yoshikawa; Seiichiro Nakabayashi; Ryuzo Kawamura
  Jpn. J. Appl. Phys., Volume：58, First page：SDDI01, May 2019, [Reviewed]
  English, Scientific journal
• Light-Powered Nanoconverters Cytotoxic to Breast Cancer Cells　　　　　　　　　　　　　　　
  Alexandre R. Loukanov; Alexei G. Basnakian; Ryuzo Kawamura; Hibiki Udono; Chavdar K. Filipov; Alena V. Savenka; Todd Fite; Seiichiro Nakabayashi
  Journal of Physical Chemistry C, Volume：122, Number：14, First page：7916, Last page：7924, Apr. 2018, [Reviewed]
  American Chemical Society, English, Scientific journal
  DOI：https://doi.org/10.1021/acs.jpcc.7b11779
  Scopus：https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85045390475&origin=inward
  Scopus Citedby：https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85045390475&origin=inward
  DOI ID：10.1021/acs.jpcc.7b11779, ISSN：1932-7455, eISSN：1932-7455, SCOPUS ID：85045390475
• A New Cell Separation Method Based on Antibody-Immobilized Nanoneedle Arrays for the Detection of Intracellular Markers　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Minami Miyazaki; Keita Shimizu; Yuta Matsumoto; Yaron R. Silberberg; Ramachandra Rao Sathuluri; Masumi Iijima; Shun'ichi Ruroda; Futoshi Iwata; Takeshi Kobayashi; Chikashi Nakamura
  NANO LETTERS, Volume：17, Number：11, First page：7117, Last page：7124, Nov. 2017, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/acs.nanolett.7b03918
  DOI ID：10.1021/acs.nanolett.7b03918, ISSN：1530-6984, eISSN：1530-6992, Web of Science ID：WOS:000415029000091
• Monitoring and extraction of uranium in polluted acid mine drainage by super-paramagnetic nanoparticles coated with carbon nanodots　　　　　　　　　　　　　　　
  Alexandre Loukanov; Hibiki Udono; Ryo Takakura; Polina Mladenova; Naritaka Kobayashi; Ryuzo Kawamura; Seiichiro Nakabayashi
  JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, Volume：314, Number：2, First page：1149, Last page：1159, Nov. 2017, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1007/s10967-017-5471-z
  DOI ID：10.1007/s10967-017-5471-z, ISSN：0236-5731, eISSN：1588-2780, Web of Science ID：WOS:000413983300070
• Structural change of nonionic surfactant self-assembling at electrochemically controlled HOPG/electrolyte interface　　　　　　　　　　　　　　　
  Naritaka Kobayashi; Hirokazu Saitoh; Ryuzo Kawamura; Hiroshi Y. Yoshikawa; Seiichiro Nakabayashi
  JOURNAL OF ELECTROANALYTICAL CHEMISTRY, Volume：799, First page：444, Last page：450, Aug. 2017, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1016/j.jelechem.2017.06.046
  DOI ID：10.1016/j.jelechem.2017.06.046, ISSN：1572-6657, eISSN：1873-2569, Web of Science ID：WOS:000411847300059
• Kinesin-Driven Active Substrate Giving Stochastic Mechanical Stimuli to Cells for Characterization　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Daiki Uehara; Naritaka Kobayashi; Seiichiro Nakabayashi; Hiroshi Y. Yoshikawa
  ACS BIOMATERIALS SCIENCE & ENGINEERING, Volume：2, Number：12, First page：2333, Last page：2338, Dec. 2016, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/acsbiomaterials.6b00538
  DOI ID：10.1021/acsbiomaterials.6b00538, ISSN：2373-9878, Web of Science ID：WOS:000389789200023
• High efficiency penetration of antibody-immobilized nanoneedle thorough plasma membrane for in situ detection of cytoskeletal proteins in living cells　　　　　　　　　　　　　　　
  R. Kawamura; K. Shimizu; Y. Matsumoto; A. Yamagishi; Y. R. Silberberg; M. Iijima; S. Kuroda; K. Fukazawa; K. Ishihara; C. Nakamura
  JOURNAL OF NANOBIOTECHNOLOGY, Volume：14, First page：74, Nov. 2016, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1186/s12951-016-0226-5
  DOI ID：10.1186/s12951-016-0226-5, ISSN：1477-3155, Web of Science ID：WOS:000387731300001
• Intelligent gels: Soft and wet nanomachine of the next era　　　　　　　　　　　　　　　
  Ken-Ichi Sano; Ryuzo Kawamura; Yoshihito Osada
  Electrically Active Materials for Medical Devices, First page：253, Last page：268, Sep. 2016, [Reviewed]
  Imperial College Press, English, In book
  DOI：https://doi.org/10.1142/9781783269877_0018
  DOI ID：10.1142/9781783269877_0018, SCOPUS ID：85019842820
• Investigation on nanoscale processes on the BaF2(111) surface in various solutions by frequency modulation atomic force microscopy　　　　　　　　　　　　　　　
  Naritaka Kobayashi; Ryuzo Kawamura; Hiroshi Y. Yoshikawa; Seiichiro Nakabayashi
  JOURNAL OF APPLIED PHYSICS, Volume：119, Number：21, First page：214308, Jun. 2016, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1063/1.4953233
  DOI ID：10.1063/1.4953233, ISSN：0021-8979, eISSN：1089-7550, Web of Science ID：WOS:000378923100024
• Biomimetic Functions of Synthetic Polymer Gels
  Yoshihito Osada; Ryuzo Kawamura; Ken-Ichi Sano
  Hydrogels of Cytoskeletal Proteins, First page：73, Last page：79, Jan. 2016
  Springer International Publishing, In book
  DOI：https://doi.org/10.1007/978-3-319-27377-8_7
  DOI ID：10.1007/978-3-319-27377-8_7
• Design of Polymer Networks Involving a Photoinduced Electronic Transmission Circuit toward Artificial Photosynthesis　　　　　　　　　　　　　　　
  Kosuke Okeyoshi; Ryuzo Kawamura; Ryo Yoshida; Yoshihito Osada
  LANGMUIR, Volume：32, Number：2, First page：626, Last page：631, Jan. 2016, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/acs.langmuir.5b04326
  DOI ID：10.1021/acs.langmuir.5b04326, ISSN：0743-7463, Web of Science ID：WOS:000368563700029
• Oscillating high-aspect-ratio monolithic silicon nanoneedle array enables efficient delivery of functional bio-macromolecules into living cells　　　　　　　　　　　　　　　
  Daisuke Matsumoto; Ramachandra Rao Sathuluri; Yoshio Kato; Yaron R. Silberberg; Ryuzo Kawamura; Futoshi Iwata; Takeshi Kobayashi; Chikashi Nakamura
  SCIENTIFIC REPORTS, Volume：5, First page：15325, Oct. 2015, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1038/srep15325
  DOI ID：10.1038/srep15325, ISSN：2045-2322, Web of Science ID：WOS:000362884800001
• Effect of microtubule polymerization on photoinduced hydrogen generation　　　　　　　　　　　　　　　
  Kosuke Okeyoshi; Ryuzo Kawamura; Ryo Yoshida; Yoshihito Osada
  CHEMICAL COMMUNICATIONS, Volume：51, Number：58, First page：11607, Last page：11610, Jun. 2015, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1039/c5cc02914g
  DOI ID：10.1039/c5cc02914g, ISSN：1359-7345, eISSN：1364-548X, Web of Science ID：WOS:000357618200015
• Microtubule teardrop patterns　　　　　　　　　　　　　　　
  Kosuke Okeyoshi; Ryuzo Kawamura; Ryo Yoshida; Yoshihito Osada
  SCIENTIFIC REPORTS, Volume：5, First page：9581, Mar. 2015, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1038/srep09581
  DOI ID：10.1038/srep09581, ISSN：2045-2322, Web of Science ID：WOS:000351948000001
• Specialized nanoneedles for intracellular analysis　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Yaron R. Silberberg; Chikashi Nakamura
  Nanobiosensors and Nanobioanalyses, First page：291, Last page：303, Jan. 2015, [Reviewed]
  Springer Japan, English, In book
  DOI：https://doi.org/10.1007/978-4-431-55190-4_14
  DOI ID：10.1007/978-4-431-55190-4_14, SCOPUS ID：84955671680
• Controlling the bias of rotational motion of ring-shaped microtubule assembly　　　　　　　　　　　　　　　
  Shoki Wada; Arif Md; Rashedul Kabir; Ryuzo Kawamura; Masaki Ito; Daisuke Inoue; Kazuki Sada; Akira Kakugo
  Biomacromolecules, Volume：16, First page：374, Last page：378, Dec. 2014, [Reviewed]
  English, Scientific journal
• Effect of microtubules hierarchy on photoinduced hydrogen generation and application to artificial photosynthesis　　　　　　　　　　　　　　　
  Kosuke Okeyoshi; Kawamura Ryuzo; Ryo Yoshida; Yoshihito Osada
  Journal of Fluid Mechanics, Volume：1621, Nov. 2014, [Reviewed]
  Cambridge University Press, English, Scientific journal
  DOI：https://doi.org/10.1557/opl.2014.174
  DOI ID：10.1557/opl.2014.174, ISSN：1469-7645, SCOPUS ID：84908554921
• Thermo- and photo-enhanced microtubule formation from Ru(bpy)(3)(2+)-conjugated tubulin　　　　　　　　　　　　　　　
  Kosuke Okeyoshi; Ryuzo Kawamura; Ryo Yoshida; Yoshihito Osada
  JOURNAL OF MATERIALS CHEMISTRY B, Volume：2, Number：1, First page：41, Last page：45, Nov. 2014, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1039/c3tb21242d
  DOI ID：10.1039/c3tb21242d, ISSN：2050-750X, eISSN：2050-7518, Web of Science ID：WOS:000327607100005
• Measurement of cell adhesion force by vertical forcible detachment using an arrowhead nanoneedle and atomic force microscopy　　　　　　　　　　　　　　　
  Seunghwan Ryu; Yui Hashizume; Mari Mishima; Ryuzo Kawamura; Masato Tamura; Hirofumi Matsui; Michiya Matsusaki; Mitsuru Akashi; Chikashi Nakamura
  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, Volume：451, Number：1, First page：107, Last page：111, Aug. 2014, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1016/j.bbrc.2014.07.078
  DOI ID：10.1016/j.bbrc.2014.07.078, ISSN：0006-291X, eISSN：1090-2104, Web of Science ID：WOS:000340864200017
• Chemically cross-linked microtubule assembly shows enhanced dynamic motions on kinesins　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Ken-Ichi Sano; Kuniharu Ijiro; Yoshihito Osada
  RSC ADVANCES, Volume：4, Number：62, First page：32953, Last page：32959, Jul. 2014, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1039/c4ra04491f
  DOI ID：10.1039/c4ra04491f, ISSN：2046-2069, Web of Science ID：WOS:000341083400049
• Employing cytoskeletal treadmilling in bio-actuator　　　　　　　　　　　　　　　
  Ken-Ichi Sano; Ryuzo Kawamura; Yoshihito Osada
  Soft Actuators: Materials, Modeling, Applications, and Future Perspectives, Volume：9784431547679, First page：489, Last page：497, Jul. 2014, [Reviewed]
  Springer Japan, English, In book
  DOI：https://doi.org/10.1007/978-4-431-54767-9_35
  DOI ID：10.1007/978-4-431-54767-9_35, SCOPUS ID：84930712258
• Detection of microtubules in vivo using antibody-immobilized nanoneedles　　　　　　　　　　　　　　　
  Yaron R. Silberberg; Ryuzo Kawamura; Seunghwan Ryu; Kyoko Fukazawa; Kazuhiko Ishihara; Chikashi Nakamura
  JOURNAL OF BIOSCIENCE AND BIOENGINEERING, Volume：117, Number：1, First page：107, Last page：112, Jan. 2014, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1016/j.jbiosc.2013.06.019
  DOI ID：10.1016/j.jbiosc.2013.06.019, ISSN：1389-1723, eISSN：1347-4421, Web of Science ID：WOS:000333071300018
• Nanoneedle insertion into the cell nucleus does not induce double-strand breaks in chromosomal DNA　　　　　　　　　　　　　　　
  Seunghwan Ryu; Ryuzo Kawamura; Ryohei Naka; Yaron R. Silberberg; Noriyuki Nakamura; Chikashi Nakamura
  Journal of Bioscience and Bioengineering, Volume：116, Number：3, First page：391, Last page：396, Sep. 2013, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1016/j.jbiosc.2013.03.022
  DOI ID：10.1016/j.jbiosc.2013.03.022, ISSN：1389-1723, PubMed ID：23643618, SCOPUS ID：84881101246
• Controlled cell adhesion using a biocompatible anchor for membrane-conjugated bovine serum albumin/bovine serum albumin mixed layer　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Mari Mishima; Seunghwan Ryu; Yu Arai; Motomu Okose; Yaron R. Silberberg; Sathuluri Ramachandra Rao; Chikashi Nakamura
  Langmuir, Volume：29, Number：21, First page：6429, Last page：6433, May 2013, [Reviewed]
  DOI：https://doi.org/10.1021/la4012229
  DOI ID：10.1021/la4012229, ISSN：0743-7463, PubMed ID：23639009
• Microtubular teardrop patterning and the growing process　　　　　　　　　　　　　　　
  Kosuke Okeyoshi; Kawamura Ryuzo; Yoshihito Osada
  Materials Research Society Symposium Proceedings, Volume：1504, First page：22, Last page：28, Feb. 2013, [Reviewed]
  Materials Research Society, English, International conference proceedings
  DOI：https://doi.org/10.1557/opl.2013.243
  DOI ID：10.1557/opl.2013.243, ISSN：0272-9172, SCOPUS ID：84899871585
• 2P179 Evaluation of cell adhesion force by mechanical detachment using AFM(12. Cell biology,Poster)　　　　　　　　　　　　　　　
  Mishima Mari; Kawamura Ryuzo; Okada Tomoko; Nakamura Chikashi
  Seibutsu Butsuri, Volume：53, Number：1, First page：S188, 2013
  The Biophysical Society of Japan General Incorporated Association, English
  DOI：https://doi.org/10.2142/biophys.53.S188_5
  DOI ID：10.2142/biophys.53.S188_5, CiNii Articles ID：110009819668
• Nanopattern Fabrication of Gold on Hydrogels and Application to Tunable Photonic Crystal　　　　　　　　　　　　　　　
  Naonobu Shimamoto; Yoshito Tanaka; Hideyuki Mitomo; Ryuzo Kawamura; Kuniharu Ijiro; Keiji Sasaki; Yoshihito Osada
  ADVANCED MATERIALS, Volume：24, Number：38, First page：5243, Last page：5248, Oct. 2012, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1002/adma.201201522
  DOI ID：10.1002/adma.201201522, ISSN：0935-9648, eISSN：1521-4095, Web of Science ID：WOS:000309176800013
• Nematic growth of microtubules that changed into giant spiral structure through partial depolymerization and subsequent dynamic ordering　　　　　　　　　　　　　　　
  Kiyotaka Shigehara; Hiroki Kudoh; Saori Mori; Yoshiki Tamura; Akira Kakugo; Ryuzo Kawamura; Hidemitsu Furukawa; Jian Ping Gong; Hiroyasu Masunaga; Tomomi Masui; Satoshi Koizumi; Kazuhiro Shikinaka
  SOFT MATTER, Volume：8, Number：45, First page：11544, Last page：11551, Jul. 2012, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1039/c2sm26675j
  DOI ID：10.1039/c2sm26675j, ISSN：1744-683X, eISSN：1744-6848, Web of Science ID：WOS:000310829800018
• Formation of motile assembly of microtubules driven by kinesins　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Akira Kakugo; Kazuhiro Shikinaka; Yoshihito Osada; Jian Ping Gong
  SMART MATERIALS AND STRUCTURES, Volume：20, Number：12, First page：124007, Dec. 2011, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1088/0964-1726/20/12/124007
  DOI ID：10.1088/0964-1726/20/12/124007, ISSN：0964-1726, eISSN：1361-665X, Web of Science ID：WOS:000298140200008
• Self-Repairing Filamentous Actin Hydrogel with Hierarchical Structure　　　　　　　　　　　　　　　
  Ken-Ichi Sano; Ryuzo Kawamura; Taiki Tominaga; Naoko Oda; Kuniharu Ijiro; Yoshihito Osada
  BIOMACROMOLECULES, Volume：12, Number：12, First page：4173, Last page：4177, Dec. 2011, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/bm2009922
  DOI ID：10.1021/bm2009922, ISSN：1525-7797, eISSN：1526-4602, Web of Science ID：WOS:000297782100001
• Dynamic self-organization and polymorphism of microtubule assembly through active interactions with kinesin　　　　　　　　　　　　　　　
  Yoshiki Tamura; Ryuzo Kawamura; Kazuhiro Shikinaka; Akira Kakugo; Yoshihito Osada; Jian Ping Gong; Hiroyuki Mayama
  SOFT MATTER, Volume：7, Number：12, First page：5654, Last page：5659, May 2011, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1039/c1sm05413a
  DOI ID：10.1039/c1sm05413a, ISSN：1744-683X, eISSN：1744-6848, Web of Science ID：WOS:000291354200025
• Thermoresponsive Microtubule Hydrogel with High Hierarchical Structure　　　　　　　　　　　　　　　
  Ken-Ichi Sano; Ryuzo Kawamura; Taiki Tominaga; Hiromichi Nakagawa; Naoko Oda; Kuniharu Ijiro; Yoshihito Osada
  BIOMACROMOLECULES, Volume：12, Number：5, First page：1409, Last page：1413, May 2011, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/bm101578x
  DOI ID：10.1021/bm101578x, ISSN：1525-7797, eISSN：1526-4602, Web of Science ID：WOS:000290246400002
• 3J1458 Motility of chemically cross-linked microtubule network driven by kinesin(Bioengineering2,The 49th Annual Meeting of the Biophysical Society of Japan)　　　　　　　　　　　　　　　
  Kawamura Ryuzo; Sano Ken-ichi; Tominaga Taiki; Oda Naoko; Ijiro Kuniharu; Osada Yoshihito
  Seibutsu Butsuri, Volume：51, First page：S143, 2011
  The Biophysical Society of Japan General Incorporated Association, English
  DOI：https://doi.org/10.2142/biophys.51.S143_2
  DOI ID：10.2142/biophys.51.S143_2, CiNii Articles ID：110008903569
• Microtubule bundle formation driven by ATP: the effect of concentrations of kinesin, streptavidin and microtubules　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Akira Kakugo; Yoshihito Osada; Jian Ping Gong
  NANOTECHNOLOGY, Volume：21, Number：14, First page：145603, Apr. 2010, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1088/0957-4484/21/14/145603
  DOI ID：10.1088/0957-4484/21/14/145603, ISSN：0957-4484, eISSN：1361-6528, Web of Science ID：WOS:000275652200029
• 1P155 1D1505 Autonomous oscillation in mechanical property of actin gel(Muscle,Oral Presentations,The 48th Annual Meeting of the Biophysical Society of Japan)　　　　　　　　　　　　　　　
  Kawamura Ryuzo; Sano Ken-Ichi; Tominaga Taiki; Ijiro Kuniharu; Osada Yoshihito
  Seibutsu Butsuri, Volume：50, Number：2, First page：S46, 2010
  The Biophysical Society of Japan General Incorporated Association, English
  DOI：https://doi.org/10.2142/biophys.50.S46_5
  DOI ID：10.2142/biophys.50.S46_5, CiNii Articles ID：110008102391
• 1P156 Reversible gel-sol transition of covalently cross-linked actin hydrogel(Muscle,The 48th Annual Meeting of the Biophysical Society of Japan)　　　　　　　　　　　　　　　
  Sano Ken-Ichi; Kawamura Ryuzo; Tominaga Taiki; Oda Naoko; Ijiro Kuniharu; Osada Yoshihito
  Seibutsu Butsuri, Volume：50, Number：2, First page：S46, Last page：S47, 2010
  The Biophysical Society of Japan General Incorporated Association, English
  DOI：https://doi.org/10.2142/biophys.50.S46_6
  DOI ID：10.2142/biophys.50.S46_6, CiNii Articles ID：110008102392
• Selective Formation of a Linear-Shaped Bundle of Microtubules　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Akira Kakugo; Yoshihito Osada; Jian Ping Gong
  LANGMUIR, Volume：26, Number：1, First page：533, Last page：537, Jan. 2010, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/la902197f
  DOI ID：10.1021/la902197f, ISSN：0743-7463, Web of Science ID：WOS:000272937500072
• Formation of Well-Oriented Microtubules with Preferential Polarity in a Confined Space under a Temperature Gradient　　　　　　　　　　　　　　　
  Akira Kakugo; Yoshiki Tamura; Kazuhiro Shikinaka; Momoko Yoshida; Ryuzo Kawamura; Hidemitsu Furukawa; Yoshihito Osada; Jian Ping Gong
  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Volume：131, Number：50, First page：18089, Last page：18095, Dec. 2009, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/ja901538n
  DOI ID：10.1021/ja901538n, ISSN：0002-7863, Web of Science ID：WOS:000273615400031
• 3P-266 Thermo-reversible hydrogel formed by microtubules(Bioengineering,The 47th Annual Meeting of the Biophysical Society of Japan)　　　　　　　　　　　　　　　
  Kawamura Ryuzo; Sano Ken-Ichi; Kunita Istuki; Tominaga Taiki; Oda Naoko; Ijiro Kuniharu; Osada Yoshihito
  Seibutsu Butsuri, Volume：49, First page：S195, 2009
  The Biophysical Society of Japan General Incorporated Association, English
  DOI：https://doi.org/10.2142/biophys.49.S195_3
  DOI ID：10.2142/biophys.49.S195_3, CiNii Articles ID：110008102120
• (Dissertation) Study on dynamic sefl-assembly of microtubules by kinesin　　　　　　　　　　　　　　　
  Kawamura Ryuzo
  Hokkaido University, Dec. 2008, [Reviewed]
  English, Doctoral thesis
• Ring-shaped assembly of microtubules shows preferential counterclockwise motion　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Akira Kakugo; Kazuhiro Shikinaka; Yoshihito Osada; Jian Ping Gong
  BIOMACROMOLECULES, Volume：9, Number：9, First page：2277, Last page：2282, Sep. 2008, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1021/bm800639w
  DOI ID：10.1021/bm800639w, ISSN：1525-7797, eISSN：1526-4602, Web of Science ID：WOS:000259033700001
• Integration of Biomolecular Motors: Toward an ATP Fueled Soft Moving System　　　　　　　　　　　　　　　
  Kazuhiro Shikinaka; Ryuzo Kawamura; Akira Kakugo; Hidemitsu Furukawa; Jian Ping Gong; Yoshihito Osada
  Polymer Preprints, Japan, Volume：57, First page：106, 2008
  English, Scientific journal
• 2P161 Dynamic self-assembly of microtubule complex by kinesin : toward ATP-fueled actuator(Molecular motors,Poster Presentations)　　　　　　　　　　　　　　　
  Kawamura Ryuzo; Kakugo Akira; Furukawa Hidemitsu; Gong Jian Ping; Osada Yoshihito
  Seibutsu Butsuri, Volume：47, First page：S153, 2007
  The Biophysical Society of Japan General Incorporated Association, English
  DOI：https://doi.org/10.2142/biophys.47.S153_2
  DOI ID：10.2142/biophys.47.S153_2, CiNii Articles ID：110006562252
• Transduction of NeuroD2 protein induced neural cell differentiation　　　　　　　　　　　　　　　
  Tomohide Noda; Ryuzo Kawamura; Hisakage Funabashi; Masayasu Mie; Eiry Kobatake
  JOURNAL OF BIOTECHNOLOGY, Volume：126, Number：2, First page：230, Last page：236, Nov. 2006, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1016/j.jbiotec.2006.04.021
  DOI ID：10.1016/j.jbiotec.2006.04.021, ISSN：0168-1656, eISSN：1873-4863, Web of Science ID：WOS:000241783300012
• Doxorubicin encapsulation and diffusional release from stable, polymeric, hydrogel nanoparticles　　　　　　　　　　　　　　　
  Dimitrios Missirlis; Ryuzo Kawamura; Nicola Tirelli; Jeffrey A. Hubbell
  EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, Volume：29, Number：2, First page：120, Last page：129, Oct. 2006, [Reviewed]
  English, Scientific journal
  DOI：https://doi.org/10.1016/j.ejps.2006.06.003
  DOI ID：10.1016/j.ejps.2006.06.003, ISSN：0928-0987, Web of Science ID：WOS:000241372100004

• ポリマー材料中におけるカーボンドットのメカノクロミズム機能探索　　　　　　　　　　　　　　　
  川村隆三; LOUKANOV Alexandre
  Volume：31, 2019
  ISSN：1344-0497, J-Global ID：201902236196531935
• バーチャル電極ディスプレイの微小管滑走アッセイでの局所性評価　　　　　　　　　　　　　　　
  畑澤研太; 宮廻裕樹; 川村隆三; 星野隆行; 星野隆行
  Volume：66th, 2019
  J-Global ID：201902248990834557
• DNA-PEG脂質を介した細胞接着機構の解明-細胞組織形成の自在制御に向けて-　　　　　　　　　　　　　　　
  東郷祥大; 佐藤健; 川村隆三; 小林成貴; 中林誠一郎; 寺村裕治; 吉川洋史
  Volume：98th, 2018
  J-Global ID：201802233641288888
• DNA hybridizationが細胞接着に与える影響の解明-細胞組織形成の人為的誘導に向けて-　　　　　　　　　　　　　　　
  佐藤健; 寺村裕治; 川村隆三; 小林成貴; 中林誠一郎; 吉川洋史
  Volume：64th, 2017
  J-Global ID：201702276065767041
• DNA-PEG脂質を用いた細胞接着ダイナミクスの解明　　　　　　　　　　　　　　　
  佐藤健; 寺村裕治; 川村隆三; 中林誠一郎; 吉川洋史
  Volume：96th, 2016
  J-Global ID：201602266545753865
• Hydrogels of cytoskeletal proteins: Preparation, structure, and emergent functions　　　　　　　　　　　　　　　
  Yoshihito Osada; Ryuzo Kawamura; Ken-Ichi Sano
  Hydrogels of Cytoskeletal Proteins: Preparation, Structure, and Emergent Functions, First page：1, Last page：79, 01 Jan. 2016
  Springer International Publishing, English, Others
  DOI：https://doi.org/10.1007/978-3-319-27377-8
  DOI ID：10.1007/978-3-319-27377-8, SCOPUS ID：84958879297
• ナノニードルアレイを用いたCreタンパク質の核内輸送　　　　　　　　　　　　　　　
  松本大亮; 齋藤恵; 加藤義雄; 川村隆三; 小林健; 岩田太; 中村史
  Volume：95th, Number：3, 2015
  ISSN：0285-7626, J-Global ID：201502228386765154
• ネスチンを標的とした神経幹細胞の機械的分離技術の開発　　　　　　　　　　　　　　　
  宮崎みなみ; 清水桂太; 松本大亮; 川村隆三; 小林健; 飯嶋益巳; 黒田俊一; 岩田太; 中村史; 中村史
  Volume：82nd, 2015
  J-Global ID：201502285332423448
• 3P-206 Mechanical cell separation of undifferentiated iPS cells targeting vimentin　　　　　　　　　　　　　　　
  Shimizu Keita; Kawamura Ryuzo; Kobayashi Takeshi; Iijima Masumi; Kuroda Shun'ichi; Iwata Futoshi; Nakamura Chikashi
  Volume：67, First page：322, Last page：322, 2015
  Japanese
  CiNii Articles ID：110010009621, CiNii Books ID：AN10549378
• 1P-257 Vimentin detection from undifferentiated iPS cells using antibodyfunctionalized nanoneedle　　　　　　　　　　　　　　　
  Shimizu Keita; Kawamura Ryuzo; Iijima Masumi; Kuroda Shun'ichi; Fukazawa Kyoko; Ishihara Kazuhiko; Nakamura Chikashi
  Volume：66, First page：82, Last page：82, 2014
  Japanese
  CiNii Articles ID：110009906338, CiNii Books ID：AN10549378
• Treadmill Machine of Cytoskeletal Proteins, Toward Establishment of Bio-actuator　　　　　　　　　　　　　　　
  KAWAMURA Ryuzo; SANO Ken-Ichi; OSADA Yoshihito
  Volume：48, Number：1, First page：11, Last page：15, 05 Jan. 2013
  Japanese
  ISSN：0919-2948, CiNii Articles ID：10031146082, CiNii Books ID：AN10402165
• 2P-172 Mechanical cell separation using antibody-immobilized nanoneedle　　　　　　　　　　　　　　　
  Miyazaki Minami; Shimizu Keita; Kawamura Ryuzo; Sathuluri Ramachandra Rao; Kobayashi Takeshi; Iijima Masumi; Kuroda Shun'ichi; Fukazawa Kyoko; Ishihara Kazuhiko; Iwata Futoshi; Nakamura Chikashi
  Volume：65, First page：147, Last page：147, 2013
  Japanese
  CiNii Articles ID：110009737838, CiNii Books ID：AN10549378
• 2P-171 Controlled cell adhesion using a BAM-BSA/BSA mixed layer　　　　　　　　　　　　　　　
  Mishima Mari; Kawamura Ryuzo; Okose Motomu; Nakamura Chikashi
  Volume：65, First page：147, Last page：147, 2013
  Japanese
  CiNii Articles ID：110009737837, CiNii Books ID：AN10549378
• 2Bp15 Effect of nanoneedle oscillation on the insertion into living cells　　　　　　　　　　　　　　　
  Ryu Seung-Hwan; Silberberg Yaron; Kawamura Ryuzo; Nakamura Chikashi
  Volume：64, First page：31, Last page：31, 2012
  Japanese
  CiNii Articles ID：110009609366, CiNii Books ID：AN10549378
• 2Bp14 A method to modify nanoneedle arrays with antibodies homogeneously　　　　　　　　　　　　　　　
  Shimooku Marie; Kawamura Ryuzo; Ishihara Kazuhiko; Fukazawa Kyoko; Nakamura Chikashi
  Volume：64, First page：31, Last page：31, 2012
  Japanese
  CiNii Articles ID：110009609365, CiNii Books ID：AN10549378
• ATP駆動型ソフトアクチュエーターの創製-配向微小管の極性評価および形成メカニズムの解明-　　　　　　　　　　　　　　　
  田村圭輝; 吉田桃子; 敷中一洋; 川村隆三; 角五彰; 角五彰; 古川英光; きょう剣萍
  Volume：44th, 2010
  J-Global ID：201002246797602010
• ATP駆動型アクチュエータの創製-配向微小管集合体の作製とその極性評価-　　　　　　　　　　　　　　　
  田村圭輝; 吉田桃子; 敷中一洋; 川村隆三; 角五彰; 角五彰; 古川英光; GONG Jian Ping
  Volume：58, Number：2 Disk1, 2009
  J-Global ID：200902209211232097
• 配向微小管によるアクティブトランスポーターの創製　　　　　　　　　　　　　　　
  吉田桃子; 敷中一洋; 川村隆三; 田村圭輝; 角五彰; 角五彰; 古川英光; きょう剣萍
  Volume：43rd, 2009
  J-Global ID：200902241524606665
• ATP駆動型アクチュエータの創製-配向微小管集合体の作製とその運動評価-　　　　　　　　　　　　　　　
  吉田桃子; 田村圭輝; 敷中一洋; 川村隆三; 角五彰; 角五彰; 古川英光; GONG Jian Ping
  Volume：20th, 2009
  J-Global ID：200902252143173012
• ATP駆動型ソフトアクチュエーターの創製-配向微小管集合体の作製とその運動評価-　　　　　　　　　　　　　　　
  田村圭輝; 吉田桃子; 敷中一洋; 川村隆三; 角五彰; 角五彰; 古川英光; GONG Jian Ping
  Volume：64, Number：1, 2009
  J-Global ID：200902253094425287
• 配向微小管によるアクティブトランスポーターの創製　　　　　　　　　　　　　　　
  吉田桃子; 田村圭樹; 敷中一洋; 川村隆三; 角五彰; 角五彰; 古川英光; GONG Jian Ping
  Volume：58, Number：1 Disk1, 2009
  J-Global ID：200902254038450402
• Integration of biomolecular motors Toward an ATP fueled soft biomachine　　　　　　　　　　　　　　　
  Akira Kakugo; Kazuhiro Shikinaka; Ryuzo Kawamura; Jianping Gong
  COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, Volume：151, Number：4, First page：444, Last page：444, Dec. 2008
  English, Summary international conference
  DOI：https://doi.org/10.1016/j.cbpb.2008.09.062
  DOI ID：10.1016/j.cbpb.2008.09.062, ISSN：1096-4959, Web of Science ID：WOS:000261672100019
• 放射光小角X線散乱を用いた配向性を有する微小管集合体の構造評価　　　　　　　　　　　　　　　
  敷中一洋; 吉田桃子; 川村隆三; 角五彰; 古川英光; GONG Jian Ping; 増永啓康; 佐々木園; 佐々木園; 増井友美; 小泉智
  Volume：57, Number：2 Disk1, 2008
  J-Global ID：200902281758612202
• 配向性を有する微小管集合体の作製とその極性評価-ATP駆動型アクティブトランスポーターを目指して-　　　　　　　　　　　　　　　
  吉田桃子; 川村隆三; 敷中一洋; 角五彰; 古川英光; GONG Jian Ping
  Volume：57, Number：1 Disk1, 2008
  J-Global ID：200902299585094908
• ポリカチオンの拡散が誘起する微小管の三次元ネットワーク形成　　　　　　　　　　　　　　　
  吉田桃子; 川村隆三; 角五彰; 古川英光; きょう剣萍; きよう剣萍; 長田義仁
  Volume：41st, 2007
  J-Global ID：200902234616557923
• キネシンによる微小管の動的自己組織化-ATP駆動型アクチュエーターを目指して　　　　　　　　　　　　　　　
  川村隆三; 角五彰; 古川英光; GONG Jian Ping; GONG Jian Ping; 長田義仁
  Volume：56, Number：1 Disk1, 2007
  J-Global ID：200902255747172706

• Soft Actuators 2nd edition (Eds. Kinji Asaka & Hidenori Okuzaki)　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Ken-Ichi Sano; Yoshihito Osada, [Contributor], Chapter 40 "Employing Cytoskeletal Treadmilling in Bio-actuators"
  Springer, 2019
• Hydrogels of Cytoskeletal Proteins —Preparation, Structure, and Emergent Functions　　　　　　　　　　　　　　　
  Yoshihito Osada; Ryuzo Kawamura; Ken-Ichi Sano, [Joint work]
  Springer International Publishing, Switzerland, 2016
• 設計工学　　　　　　　　　　　　　　　
  川村隆三; 佐野健一; 長田義仁, [Joint work]
  2013
• 未来材料 11月号　　　　　　　　　　　　　　　
  川村隆三; 龔 剣萍, [Joint work]
  Nov. 2008
• Formation of motile assembly of microtubules driven by kinesins. Intelligent Materials (M Shahinpoor, H.-J Schneider)　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Akira Kakugo; Yoshihito Osada; Jian Ping Gong, [Joint work], pp. 464–477
  RSC Publishing, UK, 2007

• ATP-fueled active network of microtubules as a dynamic environemnt for cells　　　　　　　　　　　　　　　
  Ryuzo Kawamura
  2nd GLowing Polymer Symposium in KANTO, Nov. 2019, [International conference]
  English, Oral presentation
• Active network of motor proteins as artificial dynamic microenvironment for cells　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Keisuke Meguriya; Tsuyoshi Yokoyama; Daiki Uehara; Naritaka Kobayashi; Seiichiro Nakabayashi; Hiroshi Y. Yoshikawa
  ISAGMSM(The 3rd International Symposium for Advanced Gel Materials & Soft Matters), Jun. 2019, [International conference]
  English, Invited oral presentation
• Building up a Multi-Channel Flow System to Analyze Cellular　　　　　　　　　　　　　　　
  Ryuzo Kawamura; Tsuyoshi Yokoyama; Keisuke Meguriya; Naritaka Kobayashi; Seiichiro Nakabayashi; Hiroshi Y. Yoshikawa
  GelSympo2018, Aug. 2018, [Invited], [International conference]
  English, Invited oral presentation
• キネシン・微小管の運動集積化と動的細胞環境としての応用　　　　　　　　　　　　　　　
  川村 隆三
  2017, [Domestic conference]
  Japanese, Nominated symposium
• キネシン・微小管を用いた運動界面構築と細胞培養基板としての応用　　　　　　　　　　　　　　　
  川村 隆三
  2016, [Invited], [Domestic conference]
  Japanese, Nominated symposium
• 微小管でつくる水中駆動マイクロマシン　　　　　　　　　　　　　　　
  川村 隆三
  2008, [Invited], [Domestic conference]
  Japanese, Nominated symposium

• THE SOCIETY OF POLYMER SCIENCE, JAPAN
• THE BIOPHYSICAL SOCIETY OF JAPAN
• THE CHEMICAL SOCIETY OF JAPAN

• レーザー技術による機能性分子の秩序構造形成制御　　　　　　　　　　　　　　　
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Fund for the Promotion of Joint International Research (Fostering Joint International Research (B)), Fund for the Promotion of Joint International Research (Fostering Joint International Research (B)), Oct. 2019 - Mar. 2024
  Saitama University
  Grant amount(Total)：18460000, Direct funding：14200000, Indirect funding：4260000
  Grant number：19KK0128
• Development of a processor with micro-fluctuations driven by motor proteins　　　　　　　　　　　　　　　
  JKA (formerly Japan Keirin Association), Research Grant (2-years), Apr. 2021 - Mar. 2023
  Saitama University, Principal investigator
• 光物理的アプローチによる細胞骨格形成の自在制御技術の開発　　　　　　　　　　　　　　　
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory), Grant-in-Aid for Challenging Research (Exploratory), Jul. 2020 - Mar. 2023
  Saitama University
  Grant amount(Total)：6370000, Direct funding：4900000, Indirect funding：1470000
  Grant number：20K21117
• Intelligent molecular machinery on high speed molecular display　　　　　　　　　　　　　　　
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Apr. 2019 - Mar. 2023
  Hirosaki University
  Grant amount(Total)：17420000, Direct funding：13400000, Indirect funding：4020000
  Grant number：19H02100
• キネシン駆動型運動界面を利用した細胞の動的力学環境構築　　　　　　　　　　　　　　　
  Oct. 2017 - Sep. 2022
  Principal investigator
  Competitive research funding
• Development of novel index for metastatic cancer cell evaluation giving mechanical stimuli by kinesin-driven active matrix　　　　　　　　　　　　　　　
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Apr. 2019 - Mar. 2022
  Kawamura Ryuzo, Saitama University
  Grant amount(Total)：4290000, Direct funding：3300000, Indirect funding：990000
  An active matrix which was obtained by crosslinking microtubules to a network and driven by kinesin motor proteins decorated on a solid substrate was developed in this research project toward realization of mechanically active matrix to predict metastatic property of cancer cells with expectation to find a new pathological index. The driving property of the active matrix was found to agitate micro-objects actively in isotropic manner and to generate force up to several nanonewtons. In addition to the generation of microscopic fluctuation by the active matrix, micro-fluidic device was established to realize automatic liquid handling and salvage of the cells exposed to mechanical stimuli on the active matrix and separate them according to the adhesion properties in such the dynamic condition. As the active matrix can induce formation of actin aggregations in metastatic cancer cells, this cell analysis method has potential to allow detection of metastatic cancer cells.
  Grant number：19K12775
• 運動界面を利用した転移性がん細胞の変形応答評価系の開発　　　　　　　　　　　　　　　
  Oct. 2018 - Mar. 2020
  Principal investigator
  Competitive research funding
• Assembly of active substrate of kinesin and networked-microtubule with ordering　　　　　　　　　　　　　　　
  Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Apr. 2015 - Mar. 2017
  KAWAMURA Ryuzo; NAKABAYASHI Seiichiro; YOSHIKAWAW Hiroshi; KOBAYASHI Naritaka; SUGANUMA Masami, Saitama University
  Grant amount(Total)：4290000, Direct funding：3300000, Indirect funding：990000
  Using an active network of microtubules driven by kinesins on a solid surface, we explored mechanism for coordinative behavior of these motor proteins and applied the constructed system to cells as an active substrate for better understanding of cellular dynamic characters. By patterning the kinesin-coated areas at micrometer and millimeter scale on surfaces, the moving direction of microtubules and the area pattern of active network region were successfully controlled, respectively. With use of the 2D-patterning technique, areas of the active network and the adhered-cells were prepared on the same surface and mechanical stimuli of the fluctuating microtubule network was successfully applied to the neighboring cells. When cells were seeded on this active substrate, unusual deformation of cancer cells after the adhesion was observed as a response to the mechanical stimuli.
  Grant number：15K17451
• ポリマー材料中におけるカーボンドットのメカノクロミズム機能探索　　　　　　　　　　　　　　　
  2017
  Principal investigator
  Competitive research funding
• がん細胞の硬化に着目した新規転移抑制物質の探索と分子構造の解明（分担）　　　　　　　　　　　　　　　
  2016
  Competitive research funding

• 多孔質無機材料含有エラストマーおよび多孔質無機材料含有エラストマーの製造方法　　　　　　　　　　　　　　　
  Patent right
• 異種材料が接合した重合体、及びその製造方法　　　　　　　　　　　　　　　
  Patent right